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Blue Alkaline B

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Identification
Molecular formula
C18H16N6O2
CAS number
64733-77-7
IUPAC name
(6-carbamimidoyl-2-naphthyl) 4-guanidinobenzoate
State
State

The compound is a solid at room temperature, typically existing in the form of crystalline granules. It is stable under normal conditions.

Melting point (Celsius)
241.00
Melting point (Kelvin)
514.15
Boiling point (Celsius)
150.00
Boiling point (Kelvin)
423.15
General information
Molecular weight
310.35g/mol
Molar mass
310.3520g/mol
Density
1.3400g/cm3
Appearence

The compound appears as a bright blue crystal with a strikingly intense color. The crystals are typically well-formed and may appear as small granules or larger crystalline structures depending on the preparation method.

Comment on solubility

Solubility of (6-carbamimidoyl-2-naphthyl) 4-guanidinobenzoate

The solubility of (6-carbamimidoyl-2-naphthyl) 4-guanidinobenzoate, with the chemical formula C18H16N6O2, can be considered a complex topic due to the structure and functional groups present in the compound. This compound contains notable functional elements such as guanidine groups which enhance hydrogen bonding capabilities, potentially influencing its solubility properties.

In general, the solubility can be affected by several factors:

  • Polarity: The presence of polar functional groups may increase water solubility, while large hydrophobic naphthyl regions can create overall hydrophobic character, reducing solubility in polar solvents.
  • pH Effects: Guanidine groups can be protonated or deprotonated depending on the pH, impacting aqueous solubility considerably. At lower pH levels, the positive charge enhances solubility in water.
  • Temperature: Like many organic compounds, solubility may increase with temperature, allowing for more molecules to dissolve in a solvent.
  • Solvent Choice: The solubility will vary significantly between different solvents; it may be more soluble in organic solvents than in water due to hydrophobic regions.

As a result, the overall solubility of (6-carbamimidoyl-2-naphthyl) 4-guanidinobenzoate in aqueous environments is expected to be moderate due to a combination of both hydrophobic and hydrophilic interactions. However, it is essential to conduct specific solubility tests to determine its behavior in various solvents accurately. As always, considering the compound's structural nuances is crucial for understanding and predicting solubility trends.

Interesting facts

Interesting Facts about (6-carbamimidoyl-2-naphthyl) 4-guanidinobenzoate

(6-carbamimidoyl-2-naphthyl) 4-guanidinobenzoate is a fascinating compound that falls within the realm of organic chemistry, particularly known for its involvement in biological systems and pharmaceutical applications. Here are some key points to highlight:

  • Pharmacological Relevance: This compound has potential applications in drug development, especially concerning agents that modulate nitric oxide synthesis and influence metabolic pathways.
  • Dual Nature: It features both guanidine and naphthalene functionalities, making it interesting for its ability to interact with biological receptors.
  • Research Implications: Studies have suggested that compounds similar to this one could lead to breakthroughs in treating diseases related to cardiovascular health.
  • Structural Diversity: The presence of naphthyl groups contributes to its structural complexity and enhances its chemical properties, leading to unique reactivity profiles.
  • Biological Importance: Guanidine derivatives are often studied due to their stability and ability to mimic amino acids, playing crucial roles in enzyme inhibition.

As with many compounds in this category, ongoing research is exploring the full capabilities and limitations of (6-carbamimidoyl-2-naphthyl) 4-guanidinobenzoate. The future may hold significant insights into how this compound can contribute to scientific advancements, particularly in medicinal chemistry. As scientists say, "The potential applications of organic compounds hold the keys to future therapeutic breakthroughs."

Synonyms
Nafamostat
81525-10-2
Nafamostat [INN]
Nafamostatum
Nafamostatum [Latin]
Nafabelltan
Nafamostat (INN)
Nafamstat
6-Amidino2-naphthyl 4-guanidinobenzoate
Y25LQ0H97D
(6-carbamimidoylnaphthalen-2-yl) 4-(diaminomethylideneamino)benzoate
NAFAMOSTAT [MI]
p-Guanidinobenzoic acid ester with 6-hydroxy-2-naphthamidine
NAFAMOSTAT [WHO-DD]
CHEMBL273264
CKD314
6-(Aminoiminomethyl)-2-naphthalenyl 4-((aminoiminomethyl)amino)benzoate
6-carbamimidoylnaphthalen-2-yl 4-guanidinobenzoate
Benzoic acid, 4-((aminoiminomethyl)amino)-, 6-(aminoiminomethyl)-2-naphthalenyl ester
Nafamostatum (Latin)
Benzoic acid, 4-[(aminoiminomethyl)amino]-,6-(aminoiminomethyl)-2-naphthalenyl ester
(6-carbamimidoylnaphthalen-2-yl) 4-carbamimidamidobenzoate
6-carbamimidoylnaphthalen-2-yl 4-[(diaminomethylidene)amino]benzoate
CKD-314
NCGC00160398-01
UNII-Y25LQ0H97D
6-carbamimidoylnaphthalen-2-yl 4-((diaminomethylidene)amino)benzoate
6'-amidino-2-naphthyl 4-guanidinobenzoate
BSPBio_001194
SCHEMBL135503
GTPL4262
DTXSID0048420
CHEBI:135466
HMS3742K19
ALBB-027243
BCP13085
GDA52510
HY-B0190
BDBM50063698
AKOS017259237
DB12598
6-amidino-2-naphthyl p-guanidinobenzoate
NCGC00160398-02
NCGC00160398-03
NCGC00160398-04
NCGC00160398-13
BS-17665
FUT-175; FUT 175; FUT175
NS00069533
D08240
G78310
MLS-0435512.0001
AB01566816_01
BRD-K06674495-334-03-2
BRD-K06674495-334-04-0
Q15409374
6-carbamimidoylnaphthalen-2-yl 4-carbamimidamidobenzoate
4-Guanidino-benzoic acid 6-carbamimidoyl-naphthalen-2-yl ester
4-Guanidino-benzoic acid 6-carbamimidoyl-naphthalen-2-yl ester(FUT-175)
7RF
benzoic acid, 4-[(aminoiminomethyl)amino]-, 6-(aminoiminomethyl)-2-naphthalenyl ester, methanesulfonate (1:2)