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6-Bromo-7-(methylamino)isoquinoline-5,8-dione

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Identification
Molecular formula
C10H7BrN2O2
CAS number
54257-28-0
IUPAC name
6-bromo-7-(methylamino)isoquinoline-5,8-dione
State
State

At room temperature, 6-bromo-7-(methylamino)isoquinoline-5,8-dione is typically found in a solid state. It is primarily used in research and applications that require precise handling under controlled conditions.

Melting point (Celsius)
196.00
Melting point (Kelvin)
469.15
Boiling point (Celsius)
274.00
Boiling point (Kelvin)
547.15
General information
Molecular weight
269.07g/mol
Molar mass
269.0710g/mol
Density
1.8610g/cm3
Appearence

6-Bromo-7-(methylamino)isoquinoline-5,8-dione usually appears as a crystalline solid. The compound is typically yellow to light brown in color and may exhibit a powdery form when finely ground. Its appearance may vary depending on purity and specific form used in scientific research.

Comment on solubility

Solubility of 6-bromo-7-(methylamino)isoquinoline-5,8-dione

The solubility characteristics of the compound 6-bromo-7-(methylamino)isoquinoline-5,8-dione (C10H7BrN2O2) are quite intriguing and can vary significantly based on several factors:

  • Polarity: The presence of polar functional groups such as -N2O2 can enhance interactions with polar solvents, potentially increasing solubility in such mediums.
  • Temperature: As with many organic compounds, solubility may increase with temperature, allowing for greater dissolution in solvents.
  • pH Dependency: The solubility of this compound can be influenced by the pH of the solution due to the behavior of the amino group, which may become protonated in acidic solutions, thus affecting solubility.
  • Solvent Compatibility: It is vital to test solubility in various solvents, including water, ethanol, and DMSO, to ascertain the best medium for dissolution.

As a general observation, while isoquinoline derivatives can display moderate to low solubility in water, the presence of functional groups such as bromine and methylamino may introduce variability. Understanding its solubility profile is key for applications, especially in biological systems where compound bioavailability depends directly on solubility.

Interesting facts

Interesting Facts about 6-bromo-7-(methylamino)isoquinoline-5,8-dione

6-bromo-7-(methylamino)isoquinoline-5,8-dione is an intriguing compound that presents a myriad of captivating features from both a chemical and pharmacological standpoint. Here are some noteworthy facts:

  • Structural Significance: This compound belongs to the isoquinoline class, which is known for its wide range of biological activities. The presence of the bromo and methylamino groups can significantly influence its reactivity and interaction with biological targets.
  • Biological Potential: Isoquinoline derivatives often exhibit a variety of pharmacological effects, including anticancer, antimicrobial, and anti-inflammatory properties. This makes 6-bromo-7-(methylamino)isoquinoline-5,8-dione a subject of great interest in medicinal chemistry.
  • Synthetic Applications: The synthesis of this compound involves multiple steps, often leading through various intermediates. Its synthetic routes are essential for developing similar compounds with tailored properties for drug discovery.
  • Research Studies: Scientific studies have been conducted to explore its potential as a therapeutic agent. Researchers are often keen to analyze its interactions at the molecular level, which can unveil important insights regarding its biological efficacy.
  • Analogues and Derivatives: The ability to modify the structure by altering the bromo or amino groups can lead to a library of analogues, each with unique properties. This approach is instrumental in optimizing drug candidates.

In summary, 6-bromo-7-(methylamino)isoquinoline-5,8-dione encapsulates a wealth of potential, with ongoing research dedicated to unlocking its full capabilities. As science continues to delve deeper into the intricate world of chemical compounds, this molecule stands out as a beacon of curiosity and promise.

Synonyms
Caulibugulone B
6-bromo-7-(methylamino)isoquinoline-5,8-dione
662167-16-0
UPCMLD00WCaulibugB
NCGC00092053-01
CHEMBL508779
YZQJGPPACTZUKY-UHFFFAOYSA-
DTXSID10274376
CMLD4_000048
NSC731584
NSC-731584
SDCCGMLS-0091593.P001
InChI=1/C10H7BrN2O2/c1-12-8-7(11)9(14)5-2-3-13-4-6(5)10(8)15/h2-4,12H,1H3