Interesting facts
Interesting Facts About 6-Amino-5-fluoro-1H-pyrimidin-2-one
6-Amino-5-fluoro-1H-pyrimidin-2-one is a fascinating compound with a distinctive chemical structure that plays a significant role in the field of medicinal chemistry. Here are some intriguing insights into this compound:
- Essential Building Block: This compound is a derivative of pyrimidine, an important class of compounds that are widely used in the development of pharmaceuticals.
- Anti-cancer Potential: Research has indicated that compounds based on the pyrimidine structure, including 6-amino-5-fluoro-1H-pyrimidin-2-one, can possess anti-tumor properties. Scientists are exploring its potential in cancer therapy.
- Fluorine Influence: The presence of fluorine in its structure often enhances the biological activity and stability of organic molecules, making this compound an interesting subject for further studies.
- Research Focus: Ongoing studies aim to create modified analogs of this compound to discover new therapeutic agents with improved efficacy and reduced side effects.
- Structure-Activity Relationship (SAR): Understanding the SAR of this compound helps scientists to rationally design new compounds with targeted biological activities.
As a scientist or a chemistry student, delving into the properties and applications of 6-amino-5-fluoro-1H-pyrimidin-2-one opens doors to innovations in drug design and development. The intricate interplay between its molecular structure and biological activity exemplifies the complexity of medicinal compounds:
"The beauty of chemistry lies in the details of molecular interactions that can lead to unprecedented therapeutic discoveries."
In summary, 6-amino-5-fluoro-1H-pyrimidin-2-one is not just a chemical compound; it embodies the potential for groundbreaking advancements in the field of pharmacology and medicinal chemistry.
Synonyms
5-Fluorocytosine
flucytosine
2022-85-7
Fluorocytosine
Ancobon
Ancotil
5-Fluorocystosine
Flucytosin
Fluocytosine
5-Fluorocytosin
Fluorcytosine
5-FC
Alcobon
Flucytosinum
117969-88-7
4-amino-5-fluoropyrimidin-2-ol
5-fluoro cytosine
Flucitosina
Cytosine, 5-fluoro-
Ro 2-9915
4-Amino-5-fluoropyrimidin-2(1H)-one
4-Amino-5-fluoro-2(1H)-pyrimidinone
5-Flurocytosine
5-Flucytosine
2(1H)-Pyrimidinone, 4-amino-5-fluoro-
2-Hydroxy-4-amino-5-fluoropyrimidine
Ro 29915 E/265601
2-Pyrimidinol, 4-amino-5-fluoro- (9CI)
6-amino-5-fluoro-1H-pyrimidin-2-one
Flucytosinum [INN-Latin]
Ancobon (TN)
130256-61-0
Flucytosine (Ancobon)
flucytosina
4-Amino-5-fluoro-2-hydroxypyrimidine
CHEBI:5100
NSC 103805
Ro-2-9915
HSDB 3082
2(1H)-Pyrimidinone, 6-amino-5-fluoro-
2-Pyrimidinol, 4-amino-5-fluoro-
EINECS 217-968-7
MFCD00006035
Ro-29915
NSC-103805
DTXSID3023059
UNII-D83282DT06
2(1H)-Pyrimidinone, 4-amino-5-fluoro-)
NSC103805
D83282DT06
MLS000069463
DTXCID403059
2(1H)-Pyrimidinone, 5-fluoro-3,4-dihydro-4-imino- (9CI)
4-amino-5-fluoro-1,2-dihydropyrimidin-2-one
EC 217-968-7
Flucytosine [USAN)
4-Amino-5-fluoro-1H-pyrimidin-2-one
Flucytosine [USAN:USP:INN:BAN:JAN]
NCGC00016599-01
5-FLUORO-4-IMINO-1,2,3,4-TETRAHYDROPYRIMIDIN-2-ONE
Flucitosina [DCIT]
SMR000059047
CAS-2022-85-7
4-AMINO-5-FLUORO-2(1H)-PYRIMIDINE
6-amino-5-fluoro-1,2-dihydropyrimidin-2-one
FLUCYTOSINE [USAN]
Flucytosinum (INN-Latin)
FLUCYTOSINE (MART.)
FLUCYTOSINE [MART.]
FLUCYTOSINE (USP-RS)
FLUCYTOSINE [USP-RS]
Flucytosone
Ancotyl
FLUCYTOSINE (EP MONOGRAPH)
FLUCYTOSINE (USP IMPURITY)
FLUCYTOSINE [EP MONOGRAPH]
FLUCYTOSINE [USP IMPURITY]
FLUCYTOSINE (USP MONOGRAPH)
FLUCYTOSINE [USP MONOGRAPH]
Flucytosine (USAN:USP:INN:BAN:JAN)
pyrimidine, 4-amino-5-fluoro-2-hydroxy-
6-Amino-2-oxo-5-fluoropyrimidine
6-Amino-5-fluoro-2(1H)-pyrimidinone
Flourocytosine
Ancoban
4-AMINO-2-HYDROXY-5-FLUOROPYRIMIDINE
5-fluorocytocine
Flucytosine,(S)
5-fluoro-cytosine
4-Amino-5-fluoro-2-hyroxypyrimidine
Flucytosinum (Latin)
6-amino-5-fluoropyrimidin-2(1H)-one
GL663142 & 5FC
Flucytosine (Standard)
CPD000059047
ST028644
6-amino-5-fluoro-3-hydropyrimidin-2-one
Opera_ID_178
5-fluorocytosine Form I
FLUCYTOSINE [MI]
Prestwick0_000934
Prestwick1_000934
Prestwick2_000934
Prestwick3_000934
FLUCYTOSINE [INN]
FLUCYTOSINE [JAN]
5-fluorocytosine Form II
F0321
FLUCYTOSINE [HSDB]
5-Fluorocytosine (5-FC)
Flucytosine 100 microg/mL in Acetonitrile:Water
WLN: T6MVNJ DZ EF
CHEMBL1463
SCHEMBL24063
BSPBio_000868
FLUCYTOSINE [WHO-DD]
FLUCYTOSINE [WHO-IP]
MLS000759519
MLS001076503
MLS001424013
Flucytosine, 5-Fluorocytosine
SPBio_003037
EMTRICITABINE IMPURITY E
BPBio1_000956
GL663142 & 4-Amino-5-fluoropyrimidin-2(1H)-one
Flucytosine (JP18/USP/INN)
SCHEMBL14696800
HY-B0139R
D01AE21
FLUCYTOSINE [ORANGE BOOK]
J02AX01
Flucytosine for system suitability
4-amino-5-fluoro-pyrimidin-2-ol
HMS1570L10
HMS2051M04
HMS2093J05
HMS2097L10
HMS2233I14
HMS3373L05
HMS3393M04
HMS3655G17
HMS3714L10
Pharmakon1600-01505429
5-FLUOROCYTOSINE [WHO-IP]
BCP02877
Flucytosine 2.0 mg/ml in Methanol
FLUCYTOSINUM [WHO-IP LATIN]
HY-B0139
Tox21_110515
BDBM50248003
NSC759130
s1666
STK292386
AKOS004912683
AKOS005063821
AKOS015896898
AKOS030241326
Tox21_110515_1
BCP9000692
CCG-100837
CCG-213434
CS-1935
DB01099
FF02813
GS-5578
KS-1060
NC00087
NSC-759130
SB57097
Cytosine, 5-fluoro- (6CI,7CI,8CI)
NCGC00016599-02
NCGC00016599-04
NCGC00016599-05
AC-11748
BP-30254
EMTRICITABINE IMPURITY E [WHO-IP]
NCI60_000093
SY004438
BCP0726000281
DB-005380
DB-268955
DB-271174
AB00513969
NS00000532
SW197278-3
D00323
EN300-117264
H10295
AB00444223-16
AB00513969-02
AB00513969_03
AB00513969_04
5-Fluorocytosine, Vetec(TM) reagent grade, 99%
Q238490
SR-01000721885
SR-01000721885-5
4-Amino-5-fluoro-2(1H)-pyrimidine;Flucytosine;5-FC
BRD-K82143716-001-15-7
BRD-K82143716-001-19-9
BRD-K82143716-001-20-7
4-AMINO-5-FLUOROPYRIMIDIN-2(1H)-ONE [WHO-IP]
Z1201621875
Flucytosine, European Pharmacopoeia (EP) Reference Standard
2(1H)-PYRIMIDINONE, 5-FLUORO-3,4-DIHYDRO-4-IMINO-
Flucytosine, United States Pharmacopeia (USP) Reference Standard
Flucytosine, Pharmaceutical Secondary Standard; Certified Reference Material
Flucytosine for system suitability, European Pharmacopoeia (EP) Reference Standard
1LD
217-968-7
Solubility of 6-amino-5-fluoro-1H-pyrimidin-2-one
The solubility of 6-amino-5-fluoro-1H-pyrimidin-2-one (C4H4FN3O) presents interesting characteristics that are noteworthy in both laboratory and practical applications. Below are key points regarding its solubility:
In summary, while 6-amino-5-fluoro-1H-pyrimidin-2-one is expected to be soluble in various solvents, its solubility characteristics can vary based on the specific conditions. As with many chemical compounds, experimentation is crucial for determining precise solubility parameters. Always refer to reliable sources or conduct experimental procedures to ascertain the solubility under specific conditions.