6-amino-2-(p-tolylsulfonylamino)hexanamide

Identification

Molecular formula

C₁₃H₂₀N₂O₃S

CAS number

15703-82-9

IUPAC name

6-amino-2-(p-tolylsulfonylamino)hexanamide

State

At room temperature, 6-amino-2-(p-tolylsulfonylamino)hexanamide is typically found in a solid state, presenting as white to off-white crystals or powder.

Melting point (Celsius)

175.00

Melting point (Kelvin)

448.20

Boiling point (Celsius)

337.50

Boiling point (Kelvin)

610.60

General information

Molecular weight

285.39g/mol

Molar mass

285.3530g/mol

Density

1.3036g/cm³

Appearence

6-amino-2-(p-tolylsulfonylamino)hexanamide is a chemical compound that typically appears as a solid at room temperature. It is a white to off-white crystalline or powdered substance, depending on its purity and specific formulation.

Comment on solubility

Solubility of 6-amino-2-(p-tolylsulfonylamino)hexanamide

The solubility of 6-amino-2-(p-tolylsulfonylamino)hexanamide (C₁₃H₂₀N₂O₃S) can be influenced by several factors including its molecular structure and functional groups present in the compound. This substance features both amine groups and a sulfonamide moiety, which can engage in hydrogen bonding, typically enhancing its solubility in polar solvents.

Key points to consider about its solubility include:

Polar Characteristics: The presence of amino (-NH₂) and sulfonamide (-SO₂NH₂) groups can make this compound more soluble in water and other polar solvents due to strong intermolecular attractions.
Solvent Type: Generally, compounds with significant polar characteristics tend to dissolve better in polar solvents while exhibiting lower solubility in non-polar solvents.
Temperature Effects: The solubility can vary with temperature; as temperature increases, solubility often improves, making it easier for the solid to dissolve.
pH Sensitivity: The protonation state of the amino groups may alter with pH, potentially impacting solubility in aqueous conditions.

In summary, while the specific solubility value may vary, the overall characteristics of 6-amino-2-(p-tolylsulfonylamino)hexanamide suggest that it is likely to be soluble in polar solvents, with its behavior being significantly influenced by solution conditions such as pH and temperature.

Interesting facts

Interesting Facts about 6-Amino-2-(p-tolylsulfonylamino)hexanamide

6-Amino-2-(p-tolylsulfonylamino)hexanamide is a fascinating compound with notable chemical properties and potential applications. Here are some intriguing aspects of this compound:

Structural Features: This compound boasts a unique structure that includes an amino group and a sulfonamide moiety, which can play crucial roles in biological activity.
Possible Therapeutic Uses: Sulfonamides are known for their antibacterial properties. Given its structure, 6-amino-2-(p-tolylsulfonylamino)hexanamide may exhibit similar antibacterial effects, making it a candidate for further research in medicinal chemistry.
Importance in Drug Design: The presence of the p-tolylsulfonyl group could enhance the compound’s pharmacokinetic properties, such as solubility and bioavailability. This feature is essential in the design of effective pharmaceuticals.
Versatility in Synthesis: The synthesis of this compound involves versatile reactions that can serve as a teaching point for students learning about organic synthesis methods, particularly in relation to amide formation and sulfonamide chemistry.
Research Potential: Compounds with sulfonamide functionalities are actively researched for various applications, including their anti-inflammatory properties. This aspect opens up exciting possibilities for future studies on 6-amino-2-(p-tolylsulfonylamino)hexanamide.

As a compound that blends interesting structural elements with potential applications, 6-amino-2-(p-tolylsulfonylamino)hexanamide represents a captivating subject for both seasoned chemists and curious students alike. Exploring its properties could lead to significant discoveries in the fields of medicinal chemistry and organic synthesis.