Interesting facts
Exploring 6-amino-2-(fluoromethyl)-3-(o-tolyl)quinazolin-4-one
6-amino-2-(fluoromethyl)-3-(o-tolyl)quinazolin-4-one is a fascinating compound within the realm of medicinal chemistry, primarily recognized for its diverse bioactive properties. Here are some intriguing aspects of this compound:
- Pharmacological Potential: The compound exhibits a promising profile in drug discovery, specifically in the development of therapeutics targeting various diseases, including cancers and neurodegenerative disorders.
- Structural Characteristics: The unique fluoromethyl group contributes to its chemical reactivity and lipophilicity, enhancing its ability to penetrate biological membranes.
- Quinazoline Core: The quinazoline moiety is known for its biological significance, being a scaffolding structure for numerous pharmacologically active compounds. The fused ring system provides stability, making it an excellent candidate for drug development.
- Amino Functionality: The amino group in the 6-position is pivotal for interactions with biological targets, often facilitating hydrogen bonding, which is critical in receptor binding and activity.
- O-tolyl Substitution: The presence of the o-tolyl ring can modulate the compound's overall activity and selectivity, potentially paving the way for selective targeting of specific receptors.
In summary, 6-amino-2-(fluoromethyl)-3-(o-tolyl)quinazolin-4-one is not just another chemical compound; its strategic functional groups and structural composition make it an exciting subject for ongoing research. As scientists delve deeper into understanding and harnessing its properties, we can expect it to play a significant role in the future of therapeutic developments.
Synonyms
afloqualone
56287-74-2
Arofuto
Aroft
Afloqualon
Airomate
4(3H)-Quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-
Afloqualona
Afloqualonum
Afloqualone [INN:JAN]
Afloqualonum [INN-Latin]
Afloqualona [INN-Spanish]
Aflocualona
CO4U2C8ORZ
HQ 495
Airomate (TN)
6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4-one
BRN 0819769
DTXSID5022562
AFLOQUALONE [MI]
AFLOQUALONE [INN]
AFLOQUALONE [JAN]
HQ-495
AFLOQUALONE [MART.]
AFLOQUALONE [WHO-DD]
6-Amino-2-(fluoromethyl)-3-o-tolyl-4(3H)-chinazolinon
6-Amino-2-(fluoromethyl)-3-o-tolyl-4(3H)-quinazolinone
6-Amino-2-fluoromethyl-3-(o-tolyl)-4(3H)-quinazolinone
DTXCID802562
6-amino-2-(fluoromethyl)-3-(o-tolyl)quinazolin-4(3H)-one
6-Amino-2-(fluoromethyl)-3-(2-methylphenyl)-quinazolin-4-one
6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-4(3H)-Quinazolinone
6-Amino-3,4-dihydro-2-fluoromethyl-3-(2-methylphenyl)-4-chinazolinon
4(3H)-Quinazolinone, 6-amino-2-fluoromethyl-3-(o-tolyl)-
Afloqualonum (INN-Latin)
Afloqualona (INN-Spanish)
AFLOQUALONE (MART.)
C16H14FN3O
UNII-CO4U2C8ORZ
Afloqualone (Standard)
6-amino-2-(fluoromethyl)-3-(2-methylphenyl)quinazolin-4(3H)-one
Afloqualone (JP17/INN)
MLS006010086
SCHEMBL400184
CHEMBL2105918
CHEBI:31177
HY-B1833R
6-amino-2-(fluoromethyl)-3-o-tolylquinazolin-4(3H)-one
HMS3885G19
BCP13264
HY-B1833
Tox21_112447
MFCD00867693
s3663
AKOS015842375
AC-1608
CCG-267278
CS-5009
FA29178
NCGC00167443-02
AS-11726
DA-50257
SMR004701231
CAS-56287-74-2
NS00097760
D01638
D95096
SBI-0654069.0001
Q4689289
BRD-K69247067-001-01-8
2-fluoromethyl-3-(o-tolyl)-6-amino-4(3H)-quinazolinone
6-amino-2-(fluoromethyl)-3-(o-tolyl)-4(3H)-quinazolinone
6-Amino-2-fluoromethyl-3-(2-tolyl)-3H-quinazolin-4-one
4(3H)-Quinazolinone, 6-amino-2-(fluoromethyl)-3-(2-methylphenyl)-(9CI)
Solubility of 6-amino-2-(fluoromethyl)-3-(o-tolyl)quinazolin-4-one
The solubility of 6-amino-2-(fluoromethyl)-3-(o-tolyl)quinazolin-4-one (C16H13FN3O) can be influenced by several factors. Understanding its solubility properties is essential for applications in pharmaceutical and chemical industries. Here are some key points to consider:
In summary, understanding the solubility of 6-amino-2-(fluoromethyl)-3-(o-tolyl)quinazolin-4-one is crucial for its practical applications. The interplay of its functional groups, solvent interactions, and environmental conditions creates a complex solubility profile. Overall, it is anticipated that this compound displays moderate solubility in suitable solvents, but empirical testing is always recommended to ascertain exact solubility parameters.