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Histidyl-lysine

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Identification
Molecular formula
C15H27N5O4
CAS number
30346-48-4
IUPAC name
6-amino-2-[[2-[[2-(2,6-diaminohexanoylamino)acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid
State
State

Histidyl-lysine is typically found as a solid at room temperature. It is categorized as a dipeptide, comprising the amino acids histidine and lysine.

Melting point (Celsius)
290.00
Melting point (Kelvin)
563.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
299.36g/mol
Molar mass
299.3560g/mol
Density
1.3400g/cm3
Appearence

Histidyl-lysine is a white crystalline powder. It may be odorless or possess a faint characteristic odor. Its visual appearance tends to reflect the crystalline nature typical of many amino acids and dipeptides.

Comment on solubility

Solubility of 6-amino-2-[[2-[[2-(2,6-diaminohexanoylamino)acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid

The solubility of the compound 6-amino-2-[[2-[[2-(2,6-diaminohexanoylamino)acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid (C15H27N5O4) can be described as follows:

  • Polar Nature: Due to the presence of multiple amino groups and a carboxylic acid functional group, this compound exhibits polar characteristics, which generally enhance its solubility in polar solvents such as water.
  • Amino Acids Influence: As it contains amino acid-like structures, it is likely to dissolve well in aqueous solutions, especially in physiological conditions.
  • pH Dependency: The solubility may vary with pH, since the ionization of the carboxylic group and NH2 groups can significantly affect the solubility profile.
  • Potential for Hydrogen Bonding: The ability to form hydrogen bonds due to the presence of functional groups can lead to increased solubility, particularly in aqueous environments.

In summary, while specific quantitative solubility data may be limited, the structural characteristics suggest that this compound is likely soluble in water and can interact favorably with biological systems due to its polar functional groups.

Interesting facts

Interesting Facts about 6-amino-2-[[2-[[2-(2,6-diaminohexanoylamino)acetyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]hexanoic acid

This compound, often referred to in scientific literature for its diverse biological activities, is a fascinating member of the amino acid family. Here are some compelling insights:

  • Biological Significance: The structure of this compound showcases multiple functional groups that play critical roles in various biochemical processes, including protein synthesis and enzyme activity.
  • Antimicrobial Properties: Research suggests that certain derivatives of this compound exhibit promising antimicrobial properties, making them potential candidates for antibiotic development.
  • Drug Development: Due to its complex structure, this compound serves as an interesting scaffold for the synthesis of novel drug candidates, especially for targeting diseases related to amino acid metabolism.
  • Versatile Interactions: The presence of an imidazole ring contributes to the unique physicochemical interactions with proteins, offering tools for modifying molecular recognition processes, which is crucial in drug design.
  • Peptide Synthesis: Its ability to form peptide bonds makes it a critical building block in the synthesis of peptides that can be used in therapeutic interventions.

As a result, understanding the multifaceted characteristics of this compound not only enhances academic knowledge but also opens up opportunities for innovative medicinal chemistry applications. This compound exemplifies the intersection between chemistry and biology, illustrating how intricate molecular structures can lead to significant advancements in healthcare and pharmacology.

Synonyms
sparc
DivK1c_001005
SCHEMBL4958843
HMS503I11
KBio1_001005
NINDS_001005
IDI1_001005
[J Cell Biol 125: 929 (1994)]