Interesting facts
Interesting Facts About 6-Amino-1H-pyrimidin-2-one
6-Amino-1H-pyrimidin-2-one is a fascinating compound that offers a wealth of insights for both chemists and biochemists alike. Here are some noteworthy highlights:
- Structural Significance: This compound features a pyrimidine ring, which is pivotal in various biochemical processes. Pyrimidine derivatives are vital components of nucleic acids, including DNA and RNA, illustrating their importance in genetics and molecular biology.
- Biological Activity: 6-Amino-1H-pyrimidin-2-one has been studied for its potential pharmacological properties. Compounds containing the pyrimidine moiety often exhibit diverse biological activities, including antimicrobial, antiviral, and anticancer effects.
- Synthetic Routes: The synthesis of this compound can be approached through multiple methods, which can be tailored to optimize yield and purity. It typically involves the functionalization of pyrimidine derivatives, showcasing organic synthesis's intricacies.
- Research Applications: Researchers often explore this compound in the context of drug development. Its amino group can participate in various chemical reactions, making it a versatile precursor for designing new therapeutic agents.
- Role in Metabolism: Compounds like 6-amino-1H-pyrimidin-2-one are often involved in metabolic pathways. Understanding its behavior in biological systems can reveal insights into enzyme interactions and metabolic regulation.
Overall, 6-amino-1H-pyrimidin-2-one stands at the intersection of basic and applied science, embodying the complexity of chemical compounds in both nature and pharmaceuticals. As chemists continue to explore this compound, its full potential in various fields remains an exciting frontier.
Synonyms
cytosine
71-30-7
4-Amino-2-hydroxypyrimidine
4-aminopyrimidin-2(1H)-one
Cytosinimine
6-Aminopyrimidin-2(1h)-One
2(1H)-Pyrimidinone, 4-amino-
4-Amino-2(1H)-pyrimidinone
Cytosin
6-amino-1H-pyrimidin-2-one
4-aminopyrimidin-2-ol
Zytosin
MFCD00006034
4-amino-2-oxo-1,2-dihydropyrimidine
Cyt
2(1H)-pyrimidinone, 6-amino-
AI3-52281
4-amino-2-pyrimidinol
CHEBI:16040
EINECS 200-749-5
UNII-8J337D1HZY
NSC 27787
NSC-27787
8J337D1HZY
107646-83-3
DTXSID4044456
134434-40-5
107646-84-4
134434-39-2
2(1H)-Pyrimidinone, 3,4-dihydro-4-imino-, (E)- (9CI)
4-Aminopyrimidin-2-(1H)-one
DTXCID2024456
EC 200-749-5
NSC27787
2(1H)-Pyrimidinone, 3,4-dihydro-4-imino-, (Z)- (9CI)
4-Aminopyrimidin-2(1H)-one (Cytosine)
Cytosine-5,6-d2
CYTOSINE (USP-RS)
CYTOSINE [USP-RS]
pyrimidine, 4-amino-2-hydroxy-
SMR000857094
4-Amino-1H-pyrimidin-2-one
LAMIVUDINE IMPURITY E (EP IMPURITY)
LAMIVUDINE IMPURITY E [EP IMPURITY]
LAMIVUDINE IMPURITY C (USP IMPURITY)
LAMIVUDINE IMPURITY C [USP IMPURITY]
aminopyrimidone
iminopyrimidinone
3h-cytosine
66460-21-7
Cytosine (8CI)
4-amino-1,2-dihydropyrimidin-2-one
Cytosine (Standard)
Lamivudine impurity c
2-Pyrimidinol, 1,4-dihydro-4-imino-, (Z)- (9CI)
66460-18-2
Gemcitabine impurity A
2-Pyrimidinol, 1,4-dihydro-4-imino-
Cytosine, >=99%
2(1H)-Pyrimidinone, 4-amino- (9CI)
Lamivudine impurity c rs
CYTOSINE [MI]
4-amino-pyrimidin-2-ol
4-Amino-2-oxypyrimidine
2(1H)-Pyrimidinone, 3,4-dihydro-4-imino-
bmse000180
CYTOSINE [WHO-DD]
Epitope ID:167475
4-Amino-2(1H)pyrimidone
SCHEMBL4059
4-Amino-2(1H)-pyrimidone
2-Hydroxy-6-amino-pyrimidin
4-amino-3h-pyrimidin-2-one
MLS001332635
MLS001332636
CHEMBL15913
2-Pyrimidinol, 1,6-dihydro-6-imino-, (E)- (9CI)
GTPL8490
HY-I0626R
HMS2233N21
HMS3369N05
Cytosine, >=99.0% (HPLC)
ALBB-021996
BCP22793
HY-I0626
STR01426
Tox21_302139
s4893
STK366767
STL455080
6-amino-1,2-dihydropyrimidin-2-one
AKOS000120336
AKOS005443393
AKOS015896942
AC-2489
BCP9000005
CCG-266052
CS-W020703
FC03781
2-Pyrimidinol, 1,6-dihydro-6-imino-
CAS-71-30-7
CID 5274263
SRI-2354-05
NCGC00247019-01
NCGC00255926-01
66398-98-9
66460-19-3
BP-20183
Cytosine, Vetec(TM) reagent grade, 99%
NCI60_012445
SY001643
4-imino-3,4-dihydropyrimidin-2(1H)-one
DB-029615
DB-268893
DB-268963
DB-271170
DB-271171
DB-295125
NS00006844
EN300-21504
C00380
2-Pyrimidinol,1,6-dihydro-6-imino-,(E)-(9ci)
Q178425
2(1H)-Pyrimidinone,3,4-dihydro-4-imino-,(E)-(9ci)
CBA1D098-C5AB-46CE-AAC6-754572886EB2
Z203045338
Cytosine, United States Pharmacopeia (USP) Reference Standard
Cytosine, Pharmaceutical Secondary Standard; Certified Reference Material
Gemcitabine impurity A, European Pharmacopoeia (EP) Reference Standard
200-749-5
66460-16-0
Solubility of 6-amino-1H-pyrimidin-2-one
The solubility of 6-amino-1H-pyrimidin-2-one (C4H5N3O) in various solvents is a key characteristic that influences its applicability in chemical reactions and formulations. This compound exhibits:
In conclusion, understanding the solubility profile of 6-amino-1H-pyrimidin-2-one is essential for chemists working with this compound, as it affects not only its reactivity but also its extraction and purification processes. As a practical tip, one should consider solubility tests in both aqueous and organic solvents to obtain a more comprehensive understanding of its behavior in various environments.