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Thioguanosine monophosphate

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Identification
Molecular formula
C10H14N5O6PS
CAS number
85-31-9
IUPAC name
6-[6-amino-8-(sulfanylmethyl)purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
State
State

Thioguanosine monophosphate is typically in solid form at room temperature. It is known for its stability as a crystalline powder.

Melting point (Celsius)
274.00
Melting point (Kelvin)
547.15
Boiling point (Celsius)
100.00
Boiling point (Kelvin)
373.15
General information
Molecular weight
411.30g/mol
Molar mass
411.3040g/mol
Density
2.7000g/cm3
Appearence

Thioguanosine monophosphate appears as a white to off-white crystalline powder. Its appearance may vary depending on its purity and the form it is in (e.g., as a salt or hydrate).

Comment on solubility

Solubility of 6-[6-amino-8-(sulfanylmethyl)purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol (C10H14N5O6PS)

The solubility of 6-[6-amino-8-(sulfanylmethyl)purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol is influenced by various factors, making its behavior in solvent systems quite interesting. Here are some points to consider:

  • Polarity: The presence of multiple functional groups, such as hydroxyl (-OH), amino (-NH2), and phosphinyl (-P=O), suggests that this compound may exhibit significant polarity, which often correlates with higher solubility in polar solvents like water.
  • Hydrogen bonding: The hydroxyl and amino groups can engage in hydrogen bonding, potentially enhancing solubility in aqueous solutions.
  • Solvent compatibility: In addition to water, the compound might be soluble in organic solvents such as dimethyl sulfoxide (DMSO) or dimethylformamide (DMF), which are known to dissolve a wide array of organic compounds.
  • Temperature effects: Like many organic compounds, solubility may increase with temperature, which could be advantageous in certain applications where high concentrations are necessary.

In summary, the solubility characteristics of this compound can be viewed as a blend of its structural features and the nature of the solvent, congruently indicating diverse applications in both biological and chemical systems. Its interaction with various solvents deserves investigation to uncover the full extent of its solubility profile.

Interesting facts

Interesting Facts about 6-[6-amino-8-(sulfanylmethyl)purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol

This compound is a fascinating example of a complex molecular structure, which showcases the intricate relationships between organic chemistry and medicinal applications. Here are some noteworthy points regarding this unique compound:

  • Biological Significance: This compound has garnered attention for its potential role in pharmacology, particularly in the way it interacts with nucleic acids, affecting cellular processes.
  • Structural Complexity: The presence of a purine ring system combined with various functional groups, such as amino and sulfanylmethyl, highlights the diverse chemistry that can be achieved from simple molecular building blocks.
  • Intriguing Phosphorus Chemistry: The inclusion of phosphorus in this compound signals its potential utility in various chemical and biological contexts, particularly in the realm of nucleotide analogs and enzyme inhibitors.
  • Research Applications: Recent studies have explored compounds of this nature for their possible implications in treating diseases, including cancers and viral infections, making them valuable in ongoing drug development.
  • Synthetic Pathways: The synthesis of this compound presents an interesting challenge for chemists, involving multiple steps that exemplify techniques from both organic and inorganic chemistry.

As a scientist or chemistry student, delving into the nuances of this compound not only enhances our understanding of its potential effects but also uncovers the beauty of chemical synthesis and molecular interactions.

Synonyms
6-[6-amino-8-(sulfanylmethyl)purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
61866-10-2
DTXSID20274342