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Cladribine

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Identification
Molecular formula
C10H12ClN5O3
CAS number
4291-63-8
IUPAC name
6-[6-amino-8-(4-chlorophenyl)sulfanyl-purin-9-yl]-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
State
State

At room temperature, cladribine is a solid with its appearance as a crystalline powder. It is stable under standard laboratory conditions.

Melting point (Celsius)
205.00
Melting point (Kelvin)
478.15
Boiling point (Celsius)
654.50
Boiling point (Kelvin)
927.65
General information
Molecular weight
285.71g/mol
Molar mass
285.7070g/mol
Density
1.7800g/cm3
Appearence

Cladribine typically appears as a white to off-white crystalline powder. The compound is stable under ordinary conditions and must be protected from light and moisture to maintain its stability.

Comment on solubility

Solubility of 6-[6-amino-8-(4-chlorophenyl)sulfanyl-purin-9-yl]-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol

The solubility of the compound C10H12ClN5O3 can be characterized by its complex molecular structure, which consists of multiple functional groups that can influence its interaction with solvents. Due to this complexity, understanding its solubility can be quite nuanced.

Factors Influencing Solubility

Several factors can affect the solubility of this compound:

  • Polarity: The presence of chlorine and multiple nitrogen atoms makes the compound polar, which may enhance its solubility in polar solvents such as water and alcohols.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds due to its amine and hydroxyl groups can also contribute to its solubility in water.
  • Hydrophobic Interactions: The presence of a chlorophenyl group adds a hydrophobic character, which might limit its solubility in polar solvents and favor its solubility in organic solvents.

Insights into Solubility

In general, this compound might show:

  • Good solubility in polar solvents such as ethanol or acetonitrile
  • Moderate to low solubility in nonpolar solvents due to its hydrophobic characteristics

As a result, the solubility of C10H12ClN5O3 is likely to be influenced by the balance between its polar functional groups and hydrophobic moieties, thus revealing its versatility in different chemical environments.

Interesting facts

Interesting Facts about 6-[6-amino-8-(4-chlorophenyl)sulfanyl-purin-9-yl]-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol

This compound is an intriguing example of a complex molecule that belongs to the category of purine derivatives. Such compounds often demonstrate significant biological activities, making them of particular interest in pharmaceutical research. Here are some fascinating aspects of this compound:

  • Pharmaceutical Potential: Compounds like this one are often studied for their potential as medicinal agents. Their complex structure can lead to unique interactions with biological targets, making them candidates for drug development.
  • Diverse Functional Groups: The molecule consists of multiple functional groups, including amino, oxido, and oxo groups. This diversity can enhance the compound's reactivity and solubility in biological systems.
  • Mechanism Exploration: Researchers are excited about uncovering the mechanisms by which such compounds exert their effects at the molecular level. Understanding these mechanisms can pave the way for the design of targeted therapies in areas such as cancer and infectious diseases.
  • Structure-Activity Relationship (SAR): The intricate arrangement of atoms influences the pharmacological activity of the compound. Studying SAR allows chemists to modify the molecule and optimize its efficacy and safety profile.
  • Broader Implications: Compounds of this nature can also provide insights into broader topics in chemistry, such as the relationships between structure and function, and the synthesis of new materials.

In conclusion, the study of 6-[6-amino-8-(4-chlorophenyl)sulfanyl-purin-9-yl]-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol is not just about understanding its chemical makeup, but also about exploring its potential to impact various fields, including medicinal chemistry, biochemistry, and pharmacology. This highlights the exciting relationship between complex chemical structures and their real-world applications.