Skip to main content

Cladribine

ADVERTISEMENT
Identification
Molecular formula
C10H12ClN5O3PS
CAS number
4291-63-8
IUPAC name
6-[6-amino-8-(4-chlorophenyl)sulfanyl-purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
State
State

Cladribine is typically found in a solid state at room temperature.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.15
Boiling point (Celsius)
557.30
Boiling point (Kelvin)
830.45
General information
Molecular weight
285.71g/mol
Molar mass
285.7070g/mol
Density
1.7900g/cm3
Appearence

Cladribine appears as a white to off-white crystalline powder. It is generally odorless.

Comment on solubility

Solubility Overview

The compound 6-[6-amino-8-(4-chlorophenyl)sulfanyl-purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol, with the chemical formula C10H12ClN5O3PS, presents an interesting profile in terms of solubility.


Key Solubility Characteristics:

  • Polarity: The presence of multiple functional groups, such as amino, hydroxy, and chlorophenyl, suggests varying degrees of polarity, potentially enhancing solubility in polar solvents.
  • Organic Solvents: Compounds containing sulfanyl and nitrogen functionalities often exhibit good solubility in organic solvents like DMSO and ethanol.
  • Aqueous Solubility: Due to the presence of hydroxyl (-OH) groups, the compound may also demonstrate some degree of solubility in water, particularly under acidic or basic conditions.
  • Influence of Chloride: The chlorophenyl group could affect solubility in organic solvents, possibly increasing lipophilicity due to the chlorine substituent.
  • Complex Formation: The ability of the compound to form complexes with metal ions can also impact its solubility behavior in specific environments.

Overall, the solubility of this compound depends heavily on the solvent system, temperature, and pH conditions. It is essential to conduct empirical solubility tests to fully understand its behavior in various media. As always, the precise conditions will dictate the solubility range, making this an intriguing subject for further experimentation and analysis.

Interesting facts

Interesting Facts about 6-[6-amino-8-(4-chlorophenyl)sulfanyl-purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol

This complex compound falls within the category of heterocyclic organic compounds and is characterized by its unique structure and multifunctional properties. Here are some fascinating insights:

  • Pharmaceutical Potential: The structure of this compound suggests it may exhibit various biological activities, making it attractive for pharmaceutical research. Compounds with purine and chlorophenyl substitutions often show important interactions in medicinal chemistry.
  • Dual Functionality: The presence of both hydroxy and amino groups indicates possible reactivity and interaction with biological systems. These functional groups can facilitate hydrogen bonding and potential catalytic activity.
  • Sulfur and Phosphorus: This compound stands out due to the incorporation of both sulfur and phosphorus within its framework. These elements can impart unique chemical properties, such as enhancing solubility and reactivity, which are crucial in biological environments.
  • Structural Diversity: The compound features a carbon framework that includes multiple rings and functional groups. This diversity often correlates with complex properties and interactions, paving the way for innovative applications in drug design and material science.
  • Research Significance: Given its intricate structure, this compound may serve as a model for studying structure-activity relationships (SAR) in medicinal chemistry, helping scientists to design more effective therapeutic agents.

In summary, 6-[6-amino-8-(4-chlorophenyl)sulfanyl-purin-9-yl]-2-hydroxy-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol is a compelling subject for investigation, with potential applications ranging from drug development to the understanding of complex biochemical processes.

Synonyms
SCHEMBL7950989
DTXSID40860584
PD034418
6-{6-Amino-8-[(4-chlorophenyl)sulfanyl]-9H-purin-9-yl}-2,7-dihydroxytetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-2-one