Acetylsalicylic acid (Aspirin) | Solubility of Things

Identification

Molecular formula

C₉H₈O₄

CAS number

50-78-2

IUPAC name

[6-[6-[5-acetamido-6-[5-acetamido-6-[(3-acetamido-4-amino-4-oxo-butanoyl)amino]-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-3,4,5-trihydroxy-tetrahydropyran-2-yl]methyl dihydrogen phosphate

State

At room temperature, acetylsalicylic acid is in a solid state. It is typically found in tablet form as an over-the-counter medication.

Melting point (Celsius)

135.00

Melting point (Kelvin)

408.15

Boiling point (Celsius)

140.00

Boiling point (Kelvin)

413.15

General information

Molecular weight

180.16g/mol

Molar mass

180.1570g/mol

Density

1.3000g/cm³

Appearence

In its pure form, acetylsalicylic acid appears as a white, crystalline solid. It is odorless when pure but may have a slight vinegar-like scent due to the decomposition of aspirin into acetic acid and salicylic acid upon exposure to moisture.

Comment on solubility

Solubility of the Compound

The solubility of the compound possessing the extensive name 6-[6-[5-acetamido-6-[5-acetamido-6-[(3-acetamido-4-amino-4-oxo-butanoyl)amino]-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-3,4,5-trihydroxy-tetrahydropyran-2-yl]methyl dihydrogen phosphate (C₉H₈O₄) is influenced by several factors:

Polarity: The presence of hydroxyl (–OH) groups suggests that the compound is likely to be polar, enhancing its solubility in polar solvents, particularly water.
Hydrophilic Character: The acetamido and phosphate functionalities contribute to a hydrophilic nature, which can further improve solubility in aqueous environments.
Complex Structure: Despite its multiple functional groups, the overall structural complexity may induce limitations on solubility, especially when facing hydrophobic interactions.
Temperature Effects: Solubility can vary with temperature; generally, increasing temperature leads to higher solubility for many compounds.

In summary, although this compound exhibits features that favor solubility, it may also encounter challenges due to its intricate structure. Therefore, experimental data would be essential for precise understanding regarding its solubility in various solvents. As the adage goes, "Solubility is key to bioavailability!"

Interesting facts

Exploring the Unique Compound: 6-[6-[5-Acetamido-6-...-2-Yl]Methyl Dihydrogen Phosphate

The compound known as 6-[6-[5-acetamido-6-[5-acetamido-6-[(3-acetamido-4-amino-4-oxo-butanoyl)amino]-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-3,4,5-trihydroxy-tetrahydropyran-2-yl]methyl dihydrogen phosphate is a fascinating structure with a complex composition, indicative of its potential biological significance. Here are some intriguing facts:

Structural Complexity: This compound features multiple functional groups such as acetamido, hydroxyl, and phosphate, showcasing the intricate chemistry involved in its formation and potential interactions.
Biological Relevance: Due to the presence of acetamido groups, it may play a role in biological processes, possibly as a precursor in various biosynthetic pathways leading to important biomolecules.
Phosphate Functionality: The incorporation of dihydrogen phosphate not only contributes to the compound's structural integrity but also positions it as a candidate for studies in energy transfer mechanisms similar to those seen in ATP (adenosine triphosphate).
Potential Applications: Given its unique structure, this compound could have applications in medicinal chemistry, agricultural sciences as a pesticide, or in the development of novel biomaterials.
Natural Products: Its components suggest that it could be synthesized from natural product sources, highlighting the potential it has for use in various natural product syntheses.

In summary, this compound exemplifies the beauty of organic chemistry through its complex interconnection of functional groups and potential applications. As research evolves, deeper insight into its biological mechanisms and practical uses is anticipated. Truly, the study of such compounds enriches our understanding of chemical science and its interdisciplinary applications.