Antibiotic G 418 | Solubility of Things

Identification

Molecular formula

C₂₀H₄₀N₄O₁₀P

CAS number

108321-42-2

IUPAC name

[6-[6-[5-acetamido-6-[5-acetamido-6-[(3-acetamido-4-amino-4-oxo-butanoyl)amino]-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-3,4,5-trihydroxy-tetrahydropyran-2-yl]methyl [3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] hydrogen phosphate

State

Antibiotic G 418, at room temperature, is typically in a solid state. It is stable under standard conditions and doesn’t evaporate or sublime easily. Its solid state is often helpful for precise measurements in laboratory settings.

Melting point (Celsius)

200.00

Melting point (Kelvin)

473.15

Boiling point (Celsius)

100.00

Boiling point (Kelvin)

373.15

General information

Molecular weight

692.71g/mol

Molar mass

692.7110g/mol

Density

1.4800g/cm³

Appearence

Antibiotic G 418 is typically supplied as a white to off-white powder. This fine powder can absorb moisture and may appear slightly sticky under humid conditions. Its appearance can vary slightly depending on the degree of crystallinity and the mode of preparation, but it generally retains a consistent powder form suitable for laboratory use.

Comment on solubility

Solubility of 6-[(6-[(5-acetamido-6-[(5-acetamido-6-[(3-acetamido-4-amino-4-oxo-butanoyl)amino]-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4-hydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-4,5-dihydroxy-2-(hydroxymethyl)tetrahydropyran-3-yl]oxy-3,4,5-trihydroxy-tetrahydropyran-2-yl]methyl [3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl] hydrogen phosphate (C₂₀H₄₀N₄O₁₀P)

The compound in question is characterized by a complex structure, which influences its solubility profile significantly. Below are some key points regarding its solubility:

Polarity: The presence of multiple hydroxyl groups and phosphate moieties increases the polarity of the molecule, suggesting good compatibility with polar solvents such as water.
pH Dependence: The solubility may be pH-dependent due to the ionizable nature of the phosphate group, which can enhance solubility in acidic or basic conditions.
Hydrogen Bonding: The ability to form hydrogen bonds with solvent molecules typically enhances solubility. This compound's structure supports such interactions, likely promoting dissolution in aqueous environments.
Hydrophobic Interactions: However, despite its polar character, the presence of acetamido and hydrophobic elements may induce some level of hydrophobic interaction, which could reduce solubility in purely aqueous solutions.

In summary, the solubility of this compound is expected to be significantly influenced by its intricate structure, with favorable solubility likely in polar solvents, and varying responses to different pH levels. Understanding its solubility behavior is essential for applications in biochemical contexts.

Interesting facts

Interesting Facts about 6-[6-[5-Acetamido-6-[5-Acetamido-6-[(3-Acetamido-4-Amino-4-Oxo-Butanoyl)Amino]-4-Hydroxy-2-(Hydroxymethyl)Tetrahydropyran-3-Yl]Oxy-4-Hydroxy-2-(Hydroxymethyl)Tetrahydropyran-3-Yl]Oxy-4,5-Dihydroxy-2-(Hydroxymethyl)Tetrahydropyran-3-Yl]Oxy-3,4,5-Trihydroxy-Tetrahydropyran-2-Yl]Methyl [3-Acetamido-4,5-Dihydroxy-6-(Hydroxymethyl)Tetrahydropyran-2-Yl] Hydrogen Phosphate

This compound, a complex organic molecule, stands out for its intricate structure and biological significance. Here are some captivating aspects of this noteworthy compound:

Structural Complexity: The compound features multiple tetrahydropyran rings embedded in its structure, which are known for their cyclic nature and ability to participate in various chemical reactions.
Biological Relevance: Its acetamido groups suggest potential roles in biological systems, particularly in relation to amino acids, which play critical roles in protein synthesis and metabolism.
Phosphate Group: The presence of a hydrogen phosphate group indicates potential applications in biochemical pathways, especially in energy transfer and cellular signaling.
Potential Therapeutic Applications: The structural motifs present may provide avenues for the design of novel pharmaceuticals or therapeutic agents targeting specific biological pathways.
Chirality: The tetrahydropyran units create chiral centers, leading to stereochemical diversity that can influence the compound's interaction with biomolecules.

As a scientist or chemistry student studying this compound, one might marvel at how such elaborate structures can exhibit unique properties and functionalities, igniting curiosity and further research into their potential uses in various fields, including pharmaceuticals and biochemistry.
Understanding these intricate details can pave the way for innovative discoveries and advancements in the chemical sciences.