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Bortezomib

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Identification
Molecular formula
C19H25BN4O4
CAS number
179324-69-7
IUPAC name
6-[6-[(4-methoxyphenyl)methyl]-2,5,8,11-tetraoxo-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.3.0]pentadecan-9-yl]hexanehydroxamic acid
State
State

At room temperature, bortezomib exists as a solid.

Melting point (Celsius)
122.00
Melting point (Kelvin)
395.15
Boiling point (Celsius)
491.60
Boiling point (Kelvin)
764.80
General information
Molecular weight
384.23g/mol
Molar mass
384.2340g/mol
Density
1.3340g/cm3
Appearence
Bortezomib appears as a white to off-white crystalline powder.
Comment on solubility

Solubility of 6-[6-[(4-methoxyphenyl)methyl]-2,5,8,11-tetraoxo-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.3.0]pentadecan-9-yl]hexanehydroxamic acid (C19H25BN4O4)

The solubility of complex organic compounds like 6-[6-[(4-methoxyphenyl)methyl]-2,5,8,11-tetraoxo-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.3.0]pentadecan-9-yl]hexanehydroxamic acid can often exhibit intriguing characteristics. Understanding its solubility can be approached through several factors:

  • Polarity: The presence of hydroxamic acid functionality and polar substituents may enhance solubility in polar solvents such as water or alcohols.
  • Hydrogen bonding: The compound's structural features may enable it to form hydrogen bonds, significantly influencing its solubility profile.
  • Temperature dependency: As with many compounds, solubility might vary with temperature; generally, higher temperatures can increase solubility in most solvents.
  • Solvent interactions: Compatibility with organic solvents like DMSO or DMF could also be noteworthy, especially for applications in chemical reactions.

In sum, it is crucial to conduct experimental evaluations to determine the precise solubility of this compound, as predictions based on structure alone can sometimes lead to unexpected results. The phrase "solubility is a balance between structure and environment" encapsulates the intricate nature of solubility behaviors in organic chemistry.

Interesting facts

Interesting Facts about 6-[6-[(4-methoxyphenyl)methyl]-2,5,8,11-tetraoxo-3-sec-butyl-1,4,7,10-tetrazabicyclo[10.3.0]pentadecan-9-yl]hexanehydroxamic acid

This intriguing compound is a prime example of the fascinating chemistry that exists within complex organic molecules. Its significant properties and potential applications make it a subject of great interest for researchers and students alike. Here are some interesting facts about this compound:

  • Structural Complexity: The compound features a highly intricate structure, characterized by a tetrazabicyclo skeleton and multiple oxo groups. This complexity can lead to unique chemical behaviors and interactions.
  • Biological Relevance: Compounds with hydroxamic acid functionality are noted for their ability to inhibit metalloenzymes, which are crucial in various biochemical pathways. This property may position this compound as a candidate for pharmaceutical research.
  • Potential Applications: The presence of a methoxyphenyl group suggests possibilities in medicinal chemistry, particularly in the design of drugs targeting specific receptors or enzymes.
  • Versatile Reactions: Hydroxamic acids can undergo a variety of transformations, allowing for the potential synthesis of related compounds and derivatives that could exhibit novel properties.

The compound exemplifies how the fusion of different functional groups can lead to versatile and impactful chemical entities. Future research may unravel further uses and mechanisms for this compound, contributing to our ever-expanding knowledge of organic chemistry.