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Uridine diphosphate glucose

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Identification
Molecular formula
C15H24N2O17P2
CAS number
133-89-1
IUPAC name
6-[[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid
State
State

Uridine diphosphate glucose is typically found in a solid state at room temperature. In nature, it is present within cells usually dissolved in aqueous solutions as it functions as a substrate in enzymatic reactions.

Melting point (Celsius)
233.00
Melting point (Kelvin)
506.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
566.30g/mol
Molar mass
566.3030g/mol
Density
2.0920g/cm3
Appearence

Uridine diphosphate glucose is typically a white powder which is notable for its biochemical applications. The powdered form may be hygroscopic, meaning it can absorb moisture from the air. It is often supplied in a buffered solution for laboratory settings.

Comment on solubility

Solubility of 6-[[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid

The solubility characteristics of the compound with the formula C15H24N2O17P2 are influenced by its complex molecular structure, which features multiple functional groups that play a significant role in its solubility behavior.

Factors Influencing Solubility:

  • Hydrophilicity: The presence of multiple hydroxyl groups (-OH) and phosphoric acid moieties enhances the hydrophilicity of the compound, making it more likely to dissolve in water.
  • Interactions with Solvent: The potential for hydrogen bonding with water molecules is significant due to the functional groups, which can lead to increased solubility in aqueous environments.
  • Ionic Considerations: If the compound ionizes in solution, the resulting ions can interact favorably with water, enhancing solubility further.

However, certain factors may limit its solubility:

  • Stability: The structural stability of the compound under various conditions may affect how readily it dissolves.
  • Concentration: At higher concentrations, the solubility may become saturated, leading to precipitation.

In summary, while the numerous functional groups suggest a good potential for solubility in polar solvents like water, experimental determination is crucial to fully characterize its solubility profile. "The balance between hydrophilicity and stability is key to understanding solubility in complex compounds."

Interesting facts

Interesting Facts about 6-[[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-3,4,5-trihydroxy-tetrahydropyran-2-carboxylic acid

This complex compound belongs to a class of molecules that intriguingly combines various functionalities, making it a fascinating subject of study in medicinal chemistry and pharmaceutical research. Here are some interesting aspects:

  • Multifunctional Nature: The compound features multiple hydroxyl groups and phosphate moieties, which are known to play crucial roles in biochemical processes, particularly in energy transfer and signaling pathways.
  • Structural Complexity: The presence of both tetrahydrofuran and tetrahydropyran rings showcases the compound's structural diversity, which often correlates with its biological activity and interaction with enzymes.
  • Potential Bioactivity: Research into similar compounds has suggested that they may exhibit antitumor and antiviral properties, primarily due to their ability to interfere with nucleic acid synthesis.
  • Phosphorylation: The phosphoryl groups in this compound may facilitate interactions with various biological macromolecules, acting as a bridge to enhance potency and selectivity in pharmaceutical applications.
  • Design of Drug Candidates: The intricate design of compounds such as this one is pivotal in the rational drug design process, where scientists aim to tailor chemical properties to achieve desired therapeutic effects.

The study of this compound not only enhances our understanding of chemical interactions but also opens up avenues for innovation in drug synthesis. As scientists continue to explore the unique characteristics of such complex molecules, we may uncover groundbreaking applications in treating various diseases.

Synonyms
2616-64-0
(2S,3S,4R,5R,6R)-6-[[[(2S,3S,4R,5R)-5-(2,4-DIOXOPYRIMIDIN-1-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHOXY-HYDROXY-PHOSPHORYL]OXY-HYDROXY-PHOSPHORYL]OXY-3,4,5-TRIHYDROXY-OXANE-2-CARBOXYLIC
SCHEMBL2787208
DTXSID50863001
HDYANYHVCAPMJV-UHFFFAOYSA-N
BCP29224
6-[[[5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
PD022583
L001063
(2R,3R,4R,5S,6R)-6-[[[(2S,3R,4R,5R)-5-(2,4-Dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid
6-((((((5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)(hydroxy)phosphoryl)oxy)(hydroxy)phosphoryl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid
6-{[{[{[5-(2,4-Dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl]oxy}(hydroxy)phosphoryl]oxy}-3,4,5-trihydroxyoxane-2-carboxylic acid