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Sulochrin

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Identification
Molecular formula
C19H20O6
CAS number
479-26-5
IUPAC name
6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoic acid
State
State

At room temperature, Sulochrin is a solid substance.

Melting point (Celsius)
193.00
Melting point (Kelvin)
466.15
Boiling point (Celsius)
298.00
Boiling point (Kelvin)
571.15
General information
Molecular weight
344.34g/mol
Molar mass
344.3440g/mol
Density
1.4200g/cm3
Appearence

Sulochrin appears as a yellow crystalline solid. It is commonly isolated from fungal sources.

Comment on solubility

Solubility of 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoic acid (C19H20O6)

The solubility of chemical compounds can often depend on a variety of factors, including the presence of polar or non-polar functional groups. In the case of 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoic acid, several considerations come into play:

  • Functional Groups: The molecule contains hydroxyl (-OH) and methoxy (-OCH3) groups, which can significantly enhance solubility in polar solvents like water due to hydrogen bonding.
  • Hydrophobic Regions: The presence of the isobenzofuran structure introduces hydrophobic characteristics, which may limit solubility in very polar solvents.
  • Acidity: As a carboxylic acid, the -COOH group may also increase solubility in basic solutions, as it can deprotonate and form a negatively charged ion, aiding in dissolution.

Based on these factors, it can be postulated that:

  • The compound is likely to be soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).
  • Moderate solubility can be anticipated in water, particularly at elevated temperatures.
  • Its solubility may vary with pH, showing increased solubility in alkaline conditions.

In summary, the solubility of C19H20O6 appears to be influenced by its complex structure, and understanding these interactions is crucial for predicting its behavior in different environments.

Interesting facts

Interesting Facts about 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoic acid

This compound, often referred to in literature for its complex structure, represents a fascinating area of study within organic chemistry. Here are some engaging aspects of this compound:

  • Educational Significance: The intricate arrangement of functional groups in its structure makes it an excellent example for students of organic chemistry to analyze reactivity patterns and synthesis pathways.
  • Potential Applications: As a derivative of the isobenzofuran class, this compound could have applications in pharmaceuticals, particularly as a precursor in the synthesis of bioactive molecules.
  • Structure-Activity Relationship (SAR): The presence of multiple hydroxyl and methoxy groups could significantly enhance its biological activity, making it a subject of interest for pharmacology studies.
  • Natural Occurrence: Compounds with similar frameworks are often found in natural products, offering insight into their roles as secondary metabolites in plants.
  • Chemical Synthesis: The synthesis of such a complex molecule typically requires creative and sophisticated methodologies, often involving multi-step reactions and protecting group strategies.

As noted by chemists, "Understanding synthetic pathways opens up new avenues for innovation in medicinal chemistry." This compound exemplifies such opportunity, inviting further exploration into its effects and applications.

In summary, 6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-isobenzofuran-5-yl)-4-methyl-hex-4-enoic acid stands as a testament to the richness of chemical diversity and the endless possibilities it presents in scientific research.

Synonyms
(Z)-Mycophenolic Acid
(4Z)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid;
Spectrum_001978
Mycophenolic acid powder
Prestwick0_000556
Prestwick1_000556
Spectrum2_000892
Spectrum3_000797
Spectrum4_000890
Oprea1_330442
KBioGR_001300
KBioSS_002544
DivK1c_000146
SPBio_000704
SPBio_002552
KBio1_000146
KBio2_002535
KBio2_005103
KBio2_007671
KBio3_001754
DTXSID70860315
NINDS_000146
HMS3267P14
HMS3656M06
HMS3744O07
HMS3870C03
6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydro-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
AKOS030242136
6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1H-2-benzofuran-5-yl)-4-methylhex-4-enoic acid
SMP1_000202
NCGC00016786-14
FH177496
NCI60_000659
PD164114
DB-046386
NS00079436
Q27164271
(4Z)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-4-hexenoic Acid
6-(4-hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methyl-hex-4-enoic acid