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Cloxacillin

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Identification
Molecular formula
C19H18ClN3O5S
CAS number
61-72-3
IUPAC name
6-[(3-indan-5-yloxy-3-oxo-2-phenyl-propanoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

At room temperature, cloxacillin is generally found in a solid state. It is supplied as a crystalline powder that is specifically designed for the formulation of pharmaceutical products, typically used in solid oral dosage forms such as capsules or tablets.

Melting point (Celsius)
178.00
Melting point (Kelvin)
451.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
435.89g/mol
Molar mass
435.8910g/mol
Density
1.3400g/cm3
Appearence

Cloxacillin typically appears as a white to off-white crystalline powder. This form makes it suitable for use in solid medication formulations, such as capsules and tablets. It is generally odorless and has a bitter taste.

Comment on solubility

Solubility of 6-[(3-indan-5-yloxy-3-oxo-2-phenyl-propanoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (C19H18ClN3O5S)

The solubility of this compound is influenced by its complex molecular structure and functional groups. Here are some key points regarding its solubility:

  • Polarity: The presence of polar functional groups, such as the carboxylic acid and amine, can enhance solubility in polar solvents like water.
  • Hydrophobic Interactions: The large hydrophobic regions, particularly from the indan and phenyl groups, may limit solubility in water but promote solubility in organic solvents.
  • pH Dependence: The carboxylic acid group may ionize at higher pH levels, which could significantly increase solubility in aqueous solutions.
  • Solubility in Aqueous vs. Organic Solvents: The compound might exhibit higher solubility in organic solvents due to hydrophobic interactions while facing challenges in water due to its complex nature.

Overall, the solubility of this compound would likely be characterized as variable; further empirical testing would be necessary to determine exact solubility profiles under different conditions.

Interesting facts

Interesting Facts about 6-[(3-Indan-5-yloxy-3-oxo-2-phenyl-propanoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This complex compound showcases an intriguing blend of organic chemistry and pharmacology. It is characterized by a unique structural framework that incorporates various functional groups, which contribute to its potential biological activity. Here are some fascinating aspects to consider:

  • Diverse Functional Groups: The compound includes a variety of functional groups such as amine, carboxylic acid, and thia-azabicyclic structures, making it a versatile candidate for drug development.
  • POSSIBLE BIOACTIVITY: Due to its multifaceted structure, this compound could exhibit a range of biological activities, including antimicrobial and anti-inflammatory effects. This potential opens up avenues for further research.
  • CHALLENGING SYNTHESIS: The synthesis of such complex molecules often involves multiple steps and careful manipulation of reaction conditions, showcasing the intricacies of organic synthesis and the skill required to accomplish it.
  • APPLICATIONS IN PHARMACEUTICS: Compounds with similar structures may be investigated for their medicinal properties, contributing to the development of new therapeutic agents targeting various conditions.

The study of such compounds not only aids in understanding their chemical behavior but also paves the way for technological advancements in medicine. As researchers delve into the specifics of this compound, they hold the potential to unlock novel therapeutic pathways and enhance our pharmaceutical toolkit.

To quote Sir Isaac Newton, "If I have seen further, it is by standing on the shoulders of giants." This sentiment resonates with the journey of discovering compounds like this one, building upon the foundational knowledge of chemistry and biology.

Synonyms
SCHEMBL4936924
DTXSID90860519
6-{3-[(2,3-Dihydro-1H-inden-5-yl)oxy]-3-oxo-2-phenylpropanamido}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid