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Dicloxacillin

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Identification
Molecular formula
C19H17Cl2N3O5S
CAS number
3116-76-5
IUPAC name
6-[[3-(2,6-dichlorophenyl)-5-methyl-isoxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
State
State

Dicloxacillin is a solid at room temperature, commonly supplied in the form of capsules or tablets for pharmaceutical use.

Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
429.50
Boiling point (Kelvin)
702.70
General information
Molecular weight
470.32g/mol
Molar mass
470.3180g/mol
Density
1.5000g/cm3
Appearence

Dicloxacillin typically appears as a white or almost white, crystalline powder. It is practically insoluble in water and sparingly soluble in alcohol.

Comment on solubility

Solubility Analysis of 6-[[3-(2,6-dichlorophenyl)-5-methyl-isoxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

The compound with the formula C19H17Cl2N3O5S presents a complex structure that influences its solubility characteristics. When considering solubility, the following factors are crucial:

  • Polarity: The presence of the chlorophenyl and isoxazole groups adds polar characteristics, which can enhance solubility in polar solvents such as water.
  • Functional Groups: The compound contains multiple functional groups like carboxylate and amino, which are known to promote solubility through hydrogen bonding with solvent molecules.
  • Hydrophobic Regions: Conversely, the presence of multiple aromatic rings contributes to hydrophobicity, potentially reducing solubility in aqueous environments.

Overall, the solubility of this compound can be summarized as follows:

  • The compound may exhibit moderate to low solubility in water but could be more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).
  • It is essential to consider the pH of the solution when assessing its solubility behavior, as ionization of the carboxylate group can vary with pH, affecting overall solubility.

As a general rule, "like dissolves like," so the choice of solvent should align with the compound's characteristics for optimal solubility.

Interesting facts

Interesting Facts about 6-[[3-(2,6-dichlorophenyl)-5-methyl-isoxazole-4-carbonyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

This compound is a fascinating example of a complex organic molecule that incorporates several distinct functional groups. Below are some interesting aspects of this chemical:

  • Multi-functional Design: This compound features multiple active sites due to the presence of an isoxazole ring and various substituent groups, making it a potential candidate in the development of pharmaceuticals.
  • Biological Activity: Compounds of this kind are often evaluated for their biological effects, which can lead to applications in medical treatments, particularly as anti-inflammatory or anticancer agents.
  • Structure-Activity Relationship: The structure of this molecule allows scientists to study how different modifications can influence its interaction with biological targets, providing valuable insights into drug design.

Additionally, the presence of a 2,6-dichlorophenyl group hints at the compound's potential for significant biological activity due to the electron-withdrawing nature of the chlorine atoms, which can enhance the molecule's ability to interact with enzymes or receptor sites.

As renowned chemist Linus Pauling once said, "The best way to have a good idea is to have lots of ideas." The intricate architecture of this compound encourages creativity in modifying and synthesizing new derivatives, opening avenues for innovative research and application.

In summary, the exploration of compounds like this not only deepens our understanding of chemistry but also paves the way for advancements in medicinal chemistry and therapeutic development. The adaptability and complexity of such molecules exemplify the dynamic nature of chemical research.

Synonyms
6-({[3-(2,6-dichlorophenyl)-5-methyl-1,2-oxazol-4-yl]carbonyl}amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
STK177287
AKOS001673186
AKOS022003330
6-[3-(2,6-DICHLOROPHENYL)-5-METHYL-1,2-OXAZOLE-4-AMIDO]-3,3-DIMETHYL-7-OXO-4-THIA-1-AZABICYCLO[3.2.0]HEPTANE-2-CARBOXYLATE