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Cloxacillin

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Identification
Molecular formula
C19H17ClN3O5S
CAS number
61-72-3
IUPAC name
6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

At room temperature, cloxacillin is typically in a solid crystalline form.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
435.88g/mol
Molar mass
435.8820g/mol
Density
1.4800g/cm3
Appearence

Cloxacillin usually appears as a white or almost white crystalline powder.

Comment on solubility

Solubility of 6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

The solubility of the compound 6-[(2,6-dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (C19H17ClN3O5S) exhibits interesting characteristics that can be attributed to its complex structure. Understanding its solubility is crucial for its applications in both medicinal chemistry and other fields. Here are some key points regarding its solubility:

  • Polarity: The presence of various functional groups, such as amide and carboxylic acid, often enhances solubility in polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds can increase solubility in water, making it potentially soluble in aqueous solutions.
  • Solvent Interaction: The compound may exhibit different solubility profiles in organic solvents influenced by the presence of the dimethoxybenzoyl group.
  • pH Influence: Solubility may vary significantly with changes in pH, particularly due to the carboxylic acid functional group.

In conclusion, while the exact solubility of this compound may vary based on conditions, it is likely to demonstrate variable solubility influenced by solvent type and environmental factors such as pH and temperature. Understanding these solubility characteristics is vital for its utility in various chemical applications.

Interesting facts

Interesting Facts About 6-[(2,6-Dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid

This fascinating compound, often referred to by its more manageable namesake, plays a significant role in medicinal chemistry due to its unique structural features and properties. Here are some interesting points about this compound:

  • Complex Structure: This compound belongs to a class of bicyclic scaffolds, with intricate cyclic features that contribute to its biological activity.
  • Potential Pharmacological Use: The presence of the thiazolidine ring in its structure is often associated with compounds that exhibit antibacterial and antifungal activities.
  • Synergistic Effect: The dimethoxybenzoyl group may enhance the lipophilicity of the molecule, improving its ability to penetrate biological membranes and potentially increasing its efficacy as a therapeutic agent.
  • Mechanism of Action: Compounds with similar structures are known to inhibit specific enzymes or proteins within pathogenic organisms, leading to a disruption in their physiological processes.
  • Research Interest: Chemists and biologists are continually exploring derivatives of this compound to optimize pharmacological properties and reduce side effects, making it a hot topic in medicinal chemistry research.

As a part of ongoing research, scientists are enthusiastic about understanding how modifications to the compound’s structure can improve its therapeutic effectiveness, with the following being key areas of focus:

  1. Studying interactions with specific molecular targets in different biological systems.
  2. Investigating the impact of various substituents on biological activity.
  3. Assessing the compound’s stability and reactivity under physiological conditions.

In conclusion, the compound 6-[(2,6-Dimethoxybenzoyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid represents a remarkable example of chemical ingenuity. Its structural complexity and potential utility in medicine create a promising avenue for further exploration and development in the field of pharmacology.

Synonyms
Methcillin
CHEMBL1626346
DTXSID70859047
6-(2,6-Dimethoxybenzamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid