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Cloxacillin

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Identification
Molecular formula
C19H17ClN3O5S
CAS number
61-72-3
IUPAC name
6-(2,2-dimethyl-5-oxo-4-phenyl-imidazolidin-1-yl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

At room temperature, cloxacillin is a solid. It is usually provided in the form of a powder for reconstitution, which can then be used in oral or injectable formulations.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.00
Boiling point (Celsius)
287.80
Boiling point (Kelvin)
561.00
General information
Molecular weight
435.87g/mol
Molar mass
435.8700g/mol
Density
1.4400g/cm3
Appearence

Cloxacillin is typically a white or almost white crystalline powder. It is hygroscopic, meaning it can absorb moisture from the atmosphere. The powder is often odorless or nearly odorless.

Comment on solubility

Solubility of 6-(2,2-dimethyl-5-oxo-4-phenyl-imidazolidin-1-yl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This compound, with the formula C19H17ClN3O5S, presents unique solubility characteristics worth exploring.


General Solubility Characteristics

Due to its complex molecular structure, the solubility of this compound can be influenced by several factors:

  • Polarity: The presence of polar functional groups, such as carboxylic acid and oximes, generally increases solubility in polar solvents like water.
  • Hydrophobic Components: The inclusion of aromatic rings and dimethyl groups adds hydrophobic character, which may reduce solubility in aqueous solutions.
  • pH Dependency: The acidic nature of the carboxylic group suggests that solubility may be pH-dependent, possibly increasing in more alkaline conditions.

Expected Behavior in Solvents

In practical terms, we can anticipate the following:

  • Higher solubility in organic solvents such as ethanol or dimethyl sulfoxide (DMSO).
  • Limited solubility in water, especially at lower temperatures.
  • Potential for salt formation may enhance solubility in polar solvents, making it more versatile in various chemical applications.

It is vital to consider these factors when assessing the solubility of this compound in a laboratory or industrial context, as they can significantly affect its reactivity and application potential.

Interesting facts

Interesting Facts About 6-(2,2-Dimethyl-5-oxo-4-phenyl-imidazolidin-1-yl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This unique compound, known for its complex structure, belongs to a class of molecules that exhibit remarkable pharmacological properties. Here are some interesting facts about this fascinating compound:

  • Biological Activity: Due to its intricate configuration, this compound is being studied for its potential therapeutic applications, particularly in antimicrobial and anti-inflammatory contexts.
  • Structural Diversity: The presence of both thioether and imidazolidine functionalities contributes to the compound's chemical reactivity, allowing for the synthesis of various derivatives with altered biological profiles.
  • Design Inspired by Nature: Many compounds in this family are derived from natural products, showcasing how organic chemistry often mimics biological structures to create newer drugs.
  • Uses in Research: As a synthetic intermediate, it serves as a template for the development of novel materials and drug candidates in medicinal chemistry.
  • Chirality: The compound contains several chiral centers, which may influence its pharmacodynamics and pharmacokinetics, underscoring the importance of stereochemistry in drug design.

As remarked by researchers in the field, “The journey from synthesis to application in pharmacology is often the most exciting aspect of compound research.” This compound exemplifies how intricate chemistry can lead to groundbreaking advancements in medicine.


In summary, 6-(2,2-dimethyl-5-oxo-4-phenyl-imidazolidin-1-yl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid serves as a testament to the creativity and complexity inherent in organic synthesis and its potential to impact human health positively.

Synonyms
6-(2,2-dimethyl-5-oxo-4-phenylimidazolidin-1-yl)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
CHEMBL1625673
SCHEMBL11475948
DTXSID60859814
AKOS030241959