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Terbutaline

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Identification
Molecular formula
C12H19NO3
CAS number
23031-25-6
IUPAC name
6-[2-(tert-butylamino)-1-hydroxy-ethyl]-2-(hydroxymethyl)pyridin-3-ol
State
State

At room temperature, terbutaline is typically found in a solid state as a crystalline powder.

Melting point (Celsius)
117.00
Melting point (Kelvin)
390.15
Boiling point (Celsius)
375.00
Boiling point (Kelvin)
648.15
General information
Molecular weight
225.30g/mol
Molar mass
225.2980g/mol
Density
1.0830g/cm3
Appearence

Terbutaline appears as a white or off-white crystalline powder. It is odorless or may have a slight odor.

Comment on solubility

Solubility of 6-[2-(tert-butylamino)-1-hydroxy-ethyl]-2-(hydroxymethyl)pyridin-3-ol

The compound 6-[2-(tert-butylamino)-1-hydroxy-ethyl]-2-(hydroxymethyl)pyridin-3-ol, represented by the chemical formula C12H19NO3, exhibits interesting solubility characteristics that are significant in various applications. Here are a few key points regarding its solubility:

  • Polar Nature: The presence of multiple hydroxyl groups (-OH) and an amino group (-NH) in its structure enhances its polarity, potentially increasing its solubility in polar solvents.
  • Solvent Compatibility: This compound is likely to be soluble in water and alcohols, which are both polar solvents, due to hydrogen bonding capabilities.
  • Solubility Decrease: However, the bulky tert-butylamino group may hinder solubility to some extent in more non-polar environments.

In summary, while the compound favors solubility in polar solvents, its bulky substituents could present challenges in non-polar media. Thus, its practical applications may be largely directed towards aqueous or alcohol-based solutions, making it an essential component in formulations requiring specific solubility profiles.

Interesting facts

Interesting Facts about 6-[2-(tert-butylamino)-1-hydroxy-ethyl]-2-(hydroxymethyl)pyridin-3-ol

This fascinating compound, often referenced in biochemical studies, showcases the intricate relationship between structure and function in medicinal chemistry. Here are some engaging insights into its significance:

  • Biochemical Importance: This compound is known to interact with various biological pathways, showcasing its potential as a therapeutic agent in treating certain conditions.
  • Functional Groups: The presence of a hydroxyl group and an amino group within its structure contributes to its solubility in biological environments, enhancing its ability to interact with biological macromolecules.
  • Chirality: With its complex configuration, this compound can exhibit chirality, allowing it to have varying effects in biological systems based on its enantiomers.
  • Research Applications: It has been a subject of interest in drug design and development, leading to numerous studies focused on optimizing its efficacy and reducing potential side effects.
  • Quotes from Scientists: As one researcher noted, "Understanding the subtle modifications in compounds like this one can lead to breakthroughs in pharmacology."

This compound is a testament to the intricate dance between chemistry and biology, demonstrating how seemingly simple adjustments in molecular structure can yield profound differences in biological activity.

As you delve into the world of chemistry, keep in mind the significance of such compounds – they are much more than just a collection of atoms; they hold the key to unlocking new therapeutic potentials!

Synonyms
PIRBUTEROL
38677-81-5
Pirbuterolum [INN-Latin]
Pirbuterolum
Pirbuterol [INN:BAN]
(+/-)-Pirbuterol
Pirbuterol (INN)
OG645J8RVW
6-[2-(tert-butylamino)-1-hydroxyethyl]-2-(hydroxymethyl)pyridin-3-ol
ARA-211
PIRBUTEROL [MI]
PIRBUTEROL [INN]
pyrbuterol
PIRBUTEROL [VANDF]
2-tert-Butylamino-1-(5-hydroxy-6-hydroxymethyl-2-pyridyl)ethanol
PIRBUTEROL [MART.]
Ethanol, 2-tert-butylamino-1-(5-hydroxy-6-hydroxymethyl-2-pyridyl)-
PIRBUTEROL [WHO-DD]
CHEBI:8245
DTXSID0046937
38677-81-5 (free base)
CP-2431414
Pirbuterolum (INN-Latin)
PIRBUTEROL (MART.)
(+/-)-Pirbuterol; ARA 211
2,6-Pyridinedimethanol,a6-[[(1,1-dimethylethyl)amino]methyl]-3-hydroxy-
(RS)-6-(2-(TERT-BUTYLAMINO)-1-HYDROXYETHYL)-2-(HYDROXYMETHYL)PYRIDIN-3-OL
.ALPHA.6-(((1,1-DIMETHYLETHYL)AMINO)METHYL)-3-HYDROXY-2,6-PYRIDINEDIMETHANOL
2,6-PYRIDINEDIMETHANOL, .ALPHA.6-(((1,1-DIMETHYLETHYL)AMINO)METHYL)-3-HYDROXY-
64856-15-1
NSC355078
CP 24315-1
CP-24315-1
UNII-OG645J8RVW
pirbuterolo
6-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)pyridin-3-ol
6-(2-(tert-butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)-3-pyridinol
SCHEMBL4819
()-Pirbuterol; ARA 211
GTPL7272
CHEMBL1094966
DTXCID8026937
R03CC07
VQDBNKDJNJQRDG-UHFFFAOYSA-N
AKOS040749215
DB01291
NCI60_003197
NS00003865
C07807
D08387
EN300-23818614
L013424
Q1236526
2,6-PYRIDINEDIMETHANOL, ALPHA6-(((1,1-DIMETHYLETHYL)AMINO)METHYL)-3-HYDROXY-
ALPHA6-(((1,1-DIMETHYLETHYL)AMINO)METHYL)-3-HYDROXY-2,6-PYRIDINEDIMETHANOL