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Paclitaxel

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Identification
Molecular formula
C47H51NO14
CAS number
33069-62-4
IUPAC name
6-[2-(diethylamino)ethylsulfonyl]-21-hydroxy-10-isopropyl-11,19-dimethyl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),12,17,19,25(28)-pentaene-2,8,14,23-tetrone
State
State

At room temperature, Paclitaxel is in a solid state.

Melting point (Celsius)
216.00
Melting point (Kelvin)
489.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
853.91g/mol
Molar mass
853.9060g/mol
Density
1.4500g/cm3
Appearence

Paclitaxel is a white to off-white crystalline powder.

Comment on solubility

Solubility of 6-[2-(diethylamino)ethylsulfonyl]-21-hydroxy-10-isopropyl-11,19-dimethyl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),12,17,19,25(28)-pentaene-2,8,14,23-tetrone

The solubility of 6-[2-(diethylamino)ethylsulfonyl]-21-hydroxy-10-isopropyl-11,19-dimethyl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),12,17,19,25(28)-pentaene-2,8,14,23-tetrone (C47H51NO14) can be analyzed through several important factors:

  • Polarity: The presence of hydroxyl and sulfonyl groups in the structure often enhances polarity, which may facilitate solubility in polar solvents, such as water.
  • Hydrogen Bonding: The functional groups likely allow for hydrogen bonding, which increases solubility in aqueous solutions.
  • Organic Solvents: Given its complex structure, the compound may also exhibit solubility in organic solvents, particularly those that can disrupt intermolecular forces, like methanol and ethanol.
  • Temperature Sensitivity: Changes in temperature can significantly affect solubility; generally, increased temperatures can improve solubility for many organic compounds.

In conclusion, while the solubility is influenced by multiple factors, it is important to consider both the chemical structure and the solvent characteristics when evaluating the solubility of this compound. As a distinct observation, it may exhibit promising solubility in a range of solvents, but precise values should be determined experimentally for accurate assessment.

Interesting facts

Interesting Facts about 6-[2-(diethylamino)ethylsulfonyl]-21-hydroxy-10-isopropyl-11,19-dimethyl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.03,7]octacosa-1(27),12,17,19,25(28)-pentaene-2,8,14,23-tetrone

This fascinating compound, which boasts a complex structure, falls under the category of synthetic organic chemicals used primarily in medicinal chemistry. Its unique molecular design allows it to interact with biological systems in innovative ways.

Key Features:

  • Multifunctionality: The compound's multiple functional groups suggest possible reactivity, allowing it to be designed for specific biological targets.
  • Structural Diversity: The presence of sulfur, nitrogen, and multiple carbon rings highlights its potential as a scaffold for drug development.
  • Biological Implications: The diethylamino group hints at properties that could improve lipid solubility, possibly enhancing its pharmacokinetic profile.

Such compounds are often involved in the search for new pharmacological agents, and their study can offer insights into new therapeutic strategies. As a scientist or chemistry student, one might consider the implications of its structure on the compound’s biological activity, particularly in the development of targeted drug therapies.

Quote:

As the prominent chemist Robert H. Grubbs once said, "The best way to predict the future is to invent it." This compound may well be a step towards inventing the future of medicinal chemistry.

In conclusion, the complexity of the compound’s structure opens a myriad of avenues for research and application in various fields, making it a fascinating subject of study in chemistry and pharmacology.

Synonyms
DALFOPRISTIN
112362-50-2
(3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a- octahydro-14-hydroxy-3-isopropyl-4,12-dimethyl-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]-dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
BCP22325
6-[2-(diethylamino)ethanesulfonyl]-21-hydroxy-10-isopropyl-11,19-dimethyl-9,26-dioxa-3,15,28-triazatricyclo[23.2.1.0(3),?]octacosa-1(27),12,17,19,25(28)-pentaene-2,8,14,23-tetrone