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Proxymetacaine hydrochloride

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Identification
Molecular formula
C17H30Cl2N2OS
CAS number
5873-16-5
IUPAC name
6-[2-(diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine;dihydrochloride
State
State

At room temperature, this compound is typically in a solid state. It is usually stable under recommended storage conditions.

Melting point (Celsius)
102.00
Melting point (Kelvin)
375.15
Boiling point (Celsius)
288.50
Boiling point (Kelvin)
561.60
General information
Molecular weight
365.90g/mol
Molar mass
365.9000g/mol
Density
1.2200g/cm3
Appearence

The compound appears as a white, crystalline powder or similar solid.

Comment on solubility

Solubility of 6-[2-(diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine; dihydrochloride

The solubility of 6-[2-(diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine; dihydrochloride is an important aspect to consider for its application and effectiveness. Here's a breakdown of the solubility characteristics:

  • Solvent Compatibility: This compound is generally soluble in polar solvents. It demonstrates good solubility in water due to the presence of the dihydrochloride form, which allows it to dissociate and interact favorably with the solvent.
  • pH Dependency: The solubility can be influenced by the pH of the solution. At varying pH levels, the ionization of the amine groups can alter the degree of solubility, making it crucial to evaluate the conditions.
  • Temperature Influence: Typically, an increase in temperature enhances solubility for many compounds. Therefore, conducting experiments at elevated temperatures could yield improved dissolution rates.
  • Other Solvents: It may also exhibit varying degrees of solubility in organic solvents, although less is known regarding its performance in nonpolar environments.

In summary, while 6-[2-(diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine; dihydrochloride demonstrates favorable solubility in water, understanding the effects of pH, temperature, and other solvents is crucial for optimal utilization in chemical and pharmaceutical formulations.

Interesting facts

Interesting Facts about 6-[2-(diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine; dihydrochloride

This compound is a fascinating example of a benzothiazole derivative, which have garnered attention in the field of medicinal chemistry due to their diverse biological activities. Here are some intriguing aspects of this compound:

  • Pharmacological Potential: Compounds featuring benzothiazole scaffolds are known for their potential as pharmacological agents. They may exhibit a range of biological properties, such as antibacterial, antifungal, and even anticancer activities.
  • Structure-Activity Relationship: The presence of the diethylamino group enhances lipid solubility, which can influence the bioavailability of the compound in biological systems. This interaction provides useful insights into the structure-activity relationship (SAR) in drug design.
  • Dihydrochloride Formation: The dihydrochloride salt form increases the compound's solubility and stability, making it more suitable for pharmaceutical formulations.
  • Dual Mechanism: Compounds like this may act on multiple biological pathways, making them valuable candidates for multi-targeted therapies. This characteristic is particularly important in the treatment of complex diseases like cancer.
  • Ongoing Research: Current studies explore its efficacy against various strains of bacteria and fungi, positioning it as a potential lead compound in the development of new antibiotics.

In summary, 6-[2-(diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine; dihydrochloride exemplifies the intricate interplay of structure and function in medicinal chemistry, and its ongoing research might pave the way for innovations in therapeutic applications.

Synonyms
Diamthazole dihydrochloride
Atelor
Amikazol
Amicazol
Amycazolum
Mycotol
Dimazole dihydrochloride
136-96-9
Dimazole hydrochloride
Diamzol dihydrochloride
Diamthazole HCl
Diamthazole dihydrochlroide
UNII-3LF09TBB5W
EINECS 205-270-5
3LF09TBB5W
Ro 2-2453
DIAMTHAZOLE HYDROCHLORIDE
ASTEROL DIHYDROCHLORIDE
Dimazole dihydrochloride (JAN)
DTXSID40159627
6-(2-Diethylaminoethoxy)-2-dimethylaminobenzothiazole dihydrochloride
2-Benzothiazolamine, 6-(2-(diethylamino)ethoxy)-N,N-dimethyl-, dihydrochloride
DIMAZOLE DIHYDROCHLORIDE [JAN]
DIAMTHAZOLE DIHYDROCHLORIDE [MI]
DIAMTHAZOLE HYDROCHLORIDE [MART.]
DIMAZOLE DIHYDROCHLORIDE [WHO-DD]
Asterol (TN)
6-[2-(diethylamino)ethoxy]-N,N-dimethylbenzothiazol-2-amine dihydrochloride
BENZOTHIAZOLE, 6-(2-DIETHYLAMINOETHOXY)-2-DIMETHYLAMINO-, DIHYDROCHLORIDE
6-(2-(Diethylamino)ethoxy)-N,N-dimethylbenzothiazol-2-amine dihydrochloride
6-[2-(diethylamino)ethoxy]-N,N-dimethyl-1,3-benzothiazol-2-amine;dihydrochloride
DIAMTHAZOLE HYDROCHLORIDE (MART.)
SCHEMBL155646
CHEMBL346235
DTXCID9082118
CHEBI:31474
FZNXAQMQVKBXDR-UHFFFAOYSA-N
NS00079391
D01702
SR-01000161515
SR-01000161515-1
Q27257544
6-Diathylaminoathoxy-2-dimethylamino-benzthiazol-Dihydrochlorid
2-Benzothiazolamine, 6-(2-(diethylamino)ethoxy)-N,N-dimethyl-, dihydrochloride (9CI)
205-270-5