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Penicillin G

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Identification
Molecular formula
C16H18N2O4S
CAS number
61-33-6
IUPAC name
6-[(2-carboxy-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

At room temperature, Penicillin G is in a solid state, typically in the form of crystalline powder used for medicinal preparations.

Melting point (Celsius)
214.00
Melting point (Kelvin)
487.15
Boiling point (Celsius)
225.90
Boiling point (Kelvin)
499.05
General information
Molecular weight
356.39g/mol
Molar mass
356.3880g/mol
Density
1.4170g/cm3
Appearence

Penicillin G typically appears as white to off-white crystalline powder. It may also be available as a crystalline solid used for preparing solutions.

Comment on solubility

Solubility of 6-[(2-carboxy-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

The solubility of complex organic compounds like 6-[(2-carboxy-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (C16H18N2O4S) can significantly vary based on several factors. Understanding the solubility characteristics of this compound is essential for its application and effectiveness in various fields.

Factors Influencing Solubility:

  • Polarity: The presence of carboxylic acid groups in the molecular structure enhances its polarity, promoting solubility in polar solvents such as water.
  • Hydrogen Bonding: The compound's ability to form hydrogen bonds due to its functional groups can facilitate interactions with solvent molecules, thus improving solubility.
  • Molecular Structure: The bicyclic structure can affect how the compound packs in a solid state, which may influence its dissolution rate.

It is often observed that:

  • Weakly polar compounds tend to be soluble in non-polar solvents,
  • Highly polar or ionic compounds are typically more soluble in water or other polar solvents.

In summary, for 6-[(2-carboxy-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, one could expect a reasonable level of solubility in aqueous solutions due to its functional groups, while the precise solubility can depend greatly on environmental factors like temperature and pH. Understanding the solubility of this compound is crucial for its storage and use in various applications.

Interesting facts

Interesting Facts About 6-[(2-Carboxy-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid

This complex compound is a fascinating example of heterocyclic chemistry and exhibits structural features that make it particularly interesting for medicinal chemistry and drug development.

Key Characteristics:

  • Structural Complexity: The compound features a bicyclic structure, which is known for its unique chemical properties and potential biological activity.
  • Thiazole and Azabicyclo: Incorporating thiazole and azabicyclo moieties enhances its interaction with biological systems, possibly leading to the development of novel therapeutics.
  • Functional Groups: The presence of carboxylic acid and amine functional groups allows for various forms of chemical reactivity, making it a versatile core for further modifications.

One particularly intriguing aspect of this compound is its possible role in the development of medications targeting specific diseases. The thiazolidine and azetidine structures are of interest because they may exhibit unique interactions with enzymes and receptors within biological pathways. Researchers have noted how modifications to the core structure can lead to significant changes in the biological activity of similar compounds.

As a chemistry student or scientist, you might appreciate the creativity involved in designing molecules like this one. The compound shows how organic synthesis can be tailored to explore and hypothesize new medical treatments based on structure-activity relationships:

  • Antimicrobial Properties: Similar structures in this category have often demonstrated strong antibacterial effects.
  • Chemotherapeutic Potential: Compounds of this complexity are frequently explored for their potential as anti-cancer agents.
  • Research Implications: This compound could serve as a lead compound, driving forward the synthesis of derivatives with enhanced efficacy and reduced side effects.

In summary, 6-[(2-carboxy-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid stands as a testament to the intricate world of organic chemistry and the endless possibilities for new discoveries in drug development.

Synonyms
Oprea1_556099
CHEMBL1616445
SCHEMBL11310979
AKOS015966636
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(2-carboxy-2-phenylacetyl)amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
NCI60_000253