Cloxacillin | Solubility of Things

Identification

Molecular formula

C₁₉H₁₈ClN₃O₅S

CAS number

61-72-3

IUPAC name

6-[(2-amino-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

State

At room temperature, cloxacillin is typically found in a solid state, often as a powder.

Melting point (Celsius)

184.50

Melting point (Kelvin)

457.65

Boiling point (Celsius)

307.40

Boiling point (Kelvin)

580.55

General information

Molecular weight

442.49g/mol

Molar mass

442.4850g/mol

Density

1.3500g/cm³

Appearence

Cloxacillin is typically available as a white to off-white crystalline powder. It is often formulated into various pharmaceutical forms for medicinal use, such as capsules or tablets.

Comment on solubility

Solubility of 6-[(2-amino-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

The solubility of the compound with the chemical formula C₁₉H₁₈ClN₃O₅S is influenced by its molecular structure and functional groups. Understanding its solubility is crucial for applications in various fields, including pharmaceuticals. Here are some key considerations:

Polarity: The presence of multiple functional groups, including carboxylate and amine moieties, suggests that the compound could exhibit polar characteristics, allowing it to be soluble in polar solvents like water.
Hydrogen Bonding: The potential for hydrogen bonding, especially from the carboxylic acid and amine groups, can enhance solubility in aqueous solutions.
Solvent Effects: In organic solvents, solubility can vary greatly. The lipophilic (fat-loving) dimethyl groups may render the compound more soluble in non-polar solvents like ethanol or acetone.
Temperature Influence: As with many compounds, solubility can increase with temperature, allowing better dissolution in warmer solvents.

Overall, while the exact solubility of this compound may require experimental determination, these factors indicate a complex behavior, where the interplay of polar and non-polar characteristics can significantly influence its ability to dissolve in various media.

Interesting facts

Exploring the Unique Compound: 6-[(2-amino-2-phenyl-acetyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

This compound, known for its complex structure, belongs to an intriguing class of organic compounds that exhibit a range of biological properties. It contains multiple functional groups that contribute to its potential pharmacological activities.

Key Features:

Structural Complexity: The bicyclic structure incorporating a thioether and an amide group makes it a fascinating subject of study for chemists.
Biological Significance: It is believed that such compounds may exhibit activity as antibiotics, which makes them important in the search for new therapeutic agents.
Historical Context: The discovery and development of similar compounds have dramatically changed the potential treatments for bacterial infections, offering a glimpse into the evolving field of medicinal chemistry.
Research Interest: Due to its unique structure, it invites research focused on mechanism of action, efficacy, and the synthesis of analogs aimed at enhancing its biological effectiveness.

As a chemistry student or researcher, you might find it exciting to delve into how compounds like this one, with their intricate design, hold the promise for advancing medicinal chemistry. The exploration of their functionalities not only demonstrates the creativity involved in chemical synthesis but also emphasizes the importance of multi-functional roles in biological systems.

In the words of renowned chemist, Kurt M. L. Schmid: "The beauty of chemistry lies in its endless possibilities and the untold stories waiting to be told in every molecular structure."

Synonyms

6-{[amino(phenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate

STK177241

AKOS005410701