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Glutathione-eicosatetraenoic acid

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Identification
Molecular formula
C24H35NO7S
CAS number
51277-47-3
IUPAC name
6-(2-acetamido-2-carboxy-ethyl)sulfanyl-5-hydroxy-icosa-7,9,11,14-tetraenoic acid
State
State

At room temperature, glutathione-eicosatetraenoic acid is in a solid state. It is stable under normal conditions and should be handled with care to avoid moisture or light exposure.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
517.65g/mol
Molar mass
517.6520g/mol
Density
1.1500g/cm3
Appearence

Glutathione-eicosatetraenoic acid is typically a white to off-white crystalline powder. It has a characteristic odor. The compound is delicate and should be stored away from light and moisture to prevent degradation.

Comment on solubility

Solubility of 6-(2-acetamido-2-carboxy-ethyl)sulfanyl-5-hydroxy-icosa-7,9,11,14-tetraenoic acid

The solubility of the compound 6-(2-acetamido-2-carboxy-ethyl)sulfanyl-5-hydroxy-icosa-7,9,11,14-tetraenoic acid (C24H35NO7S) can be influenced by various factors due to its complex structure. Some notable points include:

  • Hydrophilic Functional Groups: The presence of carboxylic acid (–COOH) and amide (–CONH2) groups contributes to potential hydrogen bonding with water, enhancing solubility in polar solvents.
  • Hydrophobic Hydrocarbon Chain: The long hydrophobic carbon backbone might decrease solubility in water, demonstrating a typical behavior of compounds rich in hydrocarbons.
  • pH Dependency: The ionization state of the carboxylic acid group can vary with pH, affecting the solubility. Under acidic conditions, it might remain protonated (less soluble), while in basic conditions, it may ionize, improving solubility.
  • Solvent Interaction: Solubility can also be enhanced in organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO), where the compound can interact favorably due to its structural features.

In summary, while the solubility of 6-(2-acetamido-2-carboxy-ethyl)sulfanyl-5-hydroxy-icosa-7,9,11,14-tetraenoic acid can be significant in polar solvents due to its functional groups, the hydrophobic nature of its carbon chain presents challenges when dissolving in water. This dual behavior underscores the importance of considering both polar and nonpolar characteristics when predicting solubility.

Interesting facts

6-(2-Acetamido-2-carboxy-ethyl)sulfanyl-5-hydroxy-icosa-7,9,11,14-tetraenoic Acid

This fascinating compound, 6-(2-acetamido-2-carboxy-ethyl)sulfanyl-5-hydroxy-icosa-7,9,11,14-tetraenoic acid, is a member of a class of molecules known for their significant biochemical activities. Its complex structure features a long hydrocarbon chain with multiple double bonds, characteristic of polyunsaturated fatty acids. Here are some interesting aspects to consider:

  • Biological Role: Compounds with similar structures often play crucial roles in biological systems, particularly in cell signaling and membrane fluidity.
  • Therapeutic Potential: The presence of the acetamido and carboxy groups suggests potential for pharmaceutical applications, particularly in the development of anti-inflammatory or metabolic disorder treatments.
  • Enzymatic Pathways: This compound could be involved in important enzymatic pathways, including those related to lipid metabolism, reflecting its potential impact on health and disease.
  • Analytical Chemistry: Studying such complex molecules requires advanced analytical techniques, including mass spectrometry and nuclear magnetic resonance spectroscopy, to understand their properties and interactions.

As we analyze compounds like 6-(2-acetamido-2-carboxy-ethyl)sulfanyl-5-hydroxy-icosa-7,9,11,14-tetraenoic acid, we are reminded of the incredible diversity of chemical nature and the potential these molecules hold for advancing our understanding of biochemistry and medicinal chemistry. “The more we know about the structure and function of these compounds, the better equipped we are to harness their power.” Discovering such compounds keeps alive the spirit of inquiry that drives scientific advancement.

Synonyms
80115-95-3
N-acetyl Leukotriene E4
6-(2-Acetamido-2-carboxyethyl)sulfanyl-5-hydroxyicosa-7,9,11,14-tetraenoic acid
DTXSID801109007
DB-056408
(5S,6R,7E,9E,11Z,14Z)-6-[[(2R)-2-(Acetylamino)-2-carboxyethyl]thio]-5-hydroxy-7,9,11,14-eicosatetraenoic acid