Skip to main content

Minoxidil

ADVERTISEMENT
Identification
Molecular formula
C9H15N5O
CAS number
38304-91-5
IUPAC name
6-[2-[2-hydroxyethyl-[3-(4-nitrophenyl)propyl]amino]ethylamino]-1,3-dimethyl-pyrimidine-2,4-dione
State
State

Minoxidil is a solid at room temperature.

Melting point (Celsius)
248.00
Melting point (Kelvin)
521.15
Boiling point (Celsius)
600.00
Boiling point (Kelvin)
873.15
General information
Molecular weight
209.25g/mol
Molar mass
209.2510g/mol
Density
1.2790g/cm3
Appearence

Minoxidil appears as an off-white to white crystalline powder.

Comment on solubility

Solubility of 6-[2-[2-hydroxyethyl-[3-(4-nitrophenyl)propyl]amino]ethylamino]-1,3-dimethyl-pyrimidine-2,4-dione (C9H15N5O)

The solubility of a chemical compound is influenced by various factors such as its molecular structure, polarity, and the presence of functional groups. For the compound 6-[2-[2-hydroxyethyl-[3-(4-nitrophenyl)propyl]amino]ethylamino]-1,3-dimethyl-pyrimidine-2,4-dione, several observations can be made regarding its solubility characteristics:

  • Polarity: With multiple amine and hydroxy groups, the compound has polar characteristics, which typically enhances solubility in polar solvents, particularly water.
  • Hydrogen Bonding: The presence of hydroxyl (-OH) groups allows for hydrogen bonding, making it more soluble in aqueous solutions.
  • Functional Groups: The nitro group (-NO2) can also affect solubility, often increasing interaction with solvents due to its electronegative nature.
  • Overall Solubility: Due to its multi-functional polar nature, the compound is expected to have moderate to high solubility in water, but may exhibit variable solubility in organic solvents depending on specific conditions.

In conclusion, understanding the solubility of 6-[2-[2-hydroxyethyl-[3-(4-nitrophenyl)propyl]amino]ethylamino]-1,3-dimethyl-pyrimidine-2,4-dione requires considering its structural attributes, which significantly influence its interaction with different solvents. As with many chemical compounds, experimental data is essential to accurately define its solubility parameters in practice.

Interesting facts

Interesting Facts about 6-[2-[2-Hydroxyethyl-[3-(4-nitrophenyl)propyl]amino]ethylamino]-1,3-dimethyl-pyrimidine-2,4-dione

This intriguing compound, known for its complex structure, belongs to a class of chemicals that often showcases remarkable biological activity. Here are some captivating insights:

  • Multi-functional Groups: The presence of multiple functional groups such as amino, hydroxy, and nitro significantly enhances the compound’s reactivity, making it of interest for various chemical reactions and interactions.
  • Pharmacological Potential: Compounds similar to this one are often investigated for their pharmacological properties, which may include roles as potential therapeutic agents targeting various diseases.
  • Structural Complexity: This compound features a pyrimidine core, a structure commonly found in many biologically active molecules including nucleotides. The modification of the pyrimidine with varying substituents can lead to diverse functional properties.
  • Research Applications: The versatility of this compound opens doors to numerous research applications, particularly in the fields of medicinal chemistry where such compounds are tailored for drug discovery and development.
  • Synthesis Interest: The synthetic pathways to produce this compound can be quite intricate, involving multiple steps and reagents, indicating a rich area for study in synthetic organic chemistry.

Quote: "The beauty of chemistry lies in its ability to combine simple elements into complex and functional entities that can impact our health and environment." This statement rings particularly true when examining the molecular architecture of this compound.

The exploration of compounds like this not only exemplifies the artistry inherent in chemical synthesis but also emphasizes the importance of continuous research in uncovering new and effective applications in the medical field.

Synonyms
nifekalant
130636-43-0
Nifekalant [INN]
UNII-5VZ7GZM43E
5VZ7GZM43E
NIFEKALANT [MI]
NIFEKALANT [WHO-DD]
CHEMBL360861
DTXSID7048374
6-((2-((2-hydroxyethyl)(3-(p-nitrophenyl)propyl)amino)ethyl)amino)-1,3-dimethyl-uracil
6-((2-((2-Hydroxyethyl)(3-(p-nitrophenyl)propyl)amino)ethyl)amino)-1,3-dimethyluracil
6-((2-((2-Hydroxyethyl)(3-(4-nitrophenyl)propyl)amino)ethyl)amino)-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione
6-((2-((2-Hydroxyethyl)(3-(4-nitrophenyl)propyl)amino)ethyl)amino)-1,3-dimethylpyrimidine-2,4(1H,3H)-dione
NIFEKALANT HYDROCHLORIDE [JAN]
NCGC00164637-01
nifekalantum
1,3-dimethyl-6-((2-(N-(2-hydroxyethyl)-3-(4-nitrophenyl)propylamino)ethylamino)-2,4(1H),3H)-pyrimidinedione hydrochloride
SCHEMBL157527
DTXCID3028348
CHEBI:94575
OEBPANQZQGQPHF-UHFFFAOYSA-N
HMS2090C07
HMS3715M05
HY-B0772
BDBM50151866
AKOS022180678
CCG-221022
NCGC00164637-04
6-[2-[2-hydroxyethyl-[3-(4-nitrophenyl)propyl]amino]ethylamino]-1,3-dimethylpyrimidine-2,4-dione
DB-041977
NS00125152
AB00698502-07
AB00698502-09
Q671772
SR-01000763409
SR-01000763409-3
BRD-K32311154-001-01-0
1,3-dimethyl-6-{2-[N-(2-hydroxyethyl)-3-(4-nitrophenyl)propylamino]-eth-ylamino}-2,4-(1h,3h)-pyrimidinedione
1,3-dimethyl-6-{2-[N-(2-hydroxyethyl)-3-(4-nitrophenyl)propylamino]ethylamino}-2,4(1H,3H)-pyrimidinedione
6-(2-{(2-Hydroxy-ethyl)-[3-(4-nitro-phenyl)-propyl]-amino}-ethylamino)-1,3-dimethyl-1H-pyrimidine-2,4-dione