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Cloxacillin

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Identification
Molecular formula
C19H18ClN3O5S
CAS number
61-72-3
IUPAC name
6-[(1-aminocyclohexanecarbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
State
State

At room temperature, Cloxacillin is a solid. It is often available in the form of sodium salt for clinical use, which is soluble in water.

Melting point (Celsius)
182.00
Melting point (Kelvin)
455.15
Boiling point (Celsius)
540.00
Boiling point (Kelvin)
813.15
General information
Molecular weight
406.88g/mol
Molar mass
406.4600g/mol
Density
1.3400g/cm3
Appearence

Cloxacillin is typically found as a white to off-white crystalline powder. It is odorless and may have a slightly bitter taste. The compound can be either in a crystalline state or present as a powder.

Comment on solubility

Solubility of 6-[(1-aminocyclohexanecarbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

The solubility of the compound with the chemical formula C19H18ClN3O5S is an important aspect to consider in its applications and interactions. Solubility can significantly affect the bioavailability and reactivity of compounds, especially in pharmaceutical contexts.

Factors Influencing Solubility:

  • Polarity: The presence of polar functional groups, such as carboxylic acids and amines, typically increases solubility in polar solvents like water.
  • Hydrophobicity: Even though this compound has polar characteristics, the hydrocarbon chains can impart some degree of hydrophobicity, potentially lowering its solubility in highly polar environments.
  • Temperature: Generally, an increase in temperature can enhance the solubility of many compounds, allowing for a higher dissolution rate in solvents.
  • pH Levels: The solubility can also be significantly influenced by the pH of the solution, affecting the ionization of acidic and basic groups within the compound.

As a result, the solubility of this compound is likely to present a complex profile. It could exhibit moderate solubility in aqueous environments, while being more soluble in organic solvents that accommodate its hydrophobic regions. Conducting specific solubility tests will provide invaluable insight into its behavior across different media, which is crucial for potential applications.

Interesting facts

Interesting Facts about 6-[(1-aminocyclohexanecarbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

This intriguing chemical compound belongs to a class of molecules known for their diverse biological activities. Here are some fascinating insights into this compound:

  • Structure Complexity: The compound showcases an elaborate bicyclic structure that combines the unique features of both thiazolidine and azabicyclo frameworks. Such structural intricacies often contribute to the compound's specificity in biological interactions.
  • Potential Therapeutic Applications: Compounds with similar structures have been explored for their potential as antibiotics, particularly in combating resistant strains of bacteria. This raises significant interest in the medicinal chemistry field.
  • Mechanism of Action: The amine and carboxylic acid functional groups suggest that this compound could interact with amino acids or proteins, possibly influencing enzymatic activity or cellular signaling pathways.
  • Isomerism: Stereochemistry plays a crucial role in how this compound interacts biologically. Due to the presence of multiple chiral centers, different isomers could exhibit different levels of efficacy or toxicity.
  • Research Significance: Investigating compounds like this one can lead to valuable discoveries in synthetic routes and methodologies in organic chemistry, providing insight into how complex molecules can be designed and utilized.

As a scientist, the exploration of such compounds not only advances our understanding of chemical interactions but also opens doors for innovations in drug design and development. The fascinating interplay of structure and function in this compound emphasizes the beauty and complexity of chemistry.

Synonyms
MLS002694856
CHEMBL2143242
DTXSID40859812
HMS3085B18
SMR001550031
NS00002842
6-(((1-aminocyclohexyl)carbonyl)amino)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
6-[(1-Aminocyclohexane-1-carbonyl)amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid