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5,7-Dimethoxy-3-(4-pyridyl)quinoline

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Identification
Molecular formula
C16H14N2O2
CAS number
123572-04-7
IUPAC name
5,7-dimethoxy-3-(4-pyridyl)quinoline
State
State

At room temperature, 5,7-Dimethoxy-3-(4-pyridyl)quinoline is typically found in a solid state, presented in the form of crystals or powder. It retains its solid state under normal conditions, making it suitable for handling and storage at ambient conditions.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
369.00
Boiling point (Kelvin)
642.15
General information
Molecular weight
280.31g/mol
Molar mass
280.3080g/mol
Density
1.2400g/cm3
Appearence

5,7-Dimethoxy-3-(4-pyridyl)quinoline is a light yellow crystal or powder. It may exhibit a slightly glossy texture due to its crystallinity and can sometimes appear as cream-colored due to impurities or variations in crystallization.

Comment on solubility

Solubility of 5,7-Dimethoxy-3-(4-pyridyl)quinoline

The compound 5,7-dimethoxy-3-(4-pyridyl)quinoline, with the chemical formula C16H14N2O2, presents intriguing solubility characteristics which can be influenced by its structural components.

Here are key points regarding its solubility:

  • Polar and Non-Polar Interactions: The presence of both methoxy groups and a pyridine ring suggests that the compound might exhibit solubility in both polar and non-polar solvents. This duality often enables a range of solubility behaviors.
  • Solvent Influence: As a rule of thumb, organic compounds such as this one are generally more soluble in organic solvents like ethanol, methanol, and dimethyl sulfoxide (DMSO).
  • pH Sensitivity: The presence of the nitrogen atom in the pyridine ring could lead to changes in solubility under different pH conditions, enhancing solubility in acidic or alkaline environments.
  • Crystallinity: Crystalline substances typically have lower solubility compared to amorphous counterparts, so the structural form may also play a critical role in its solubility.

Overall, the solubility of 5,7-dimethoxy-3-(4-pyridyl)quinoline is likely to be modulated by these factors, making it essential for researchers to consider appropriate solvent systems during experiments. Understanding these solubility properties is crucial for applications in pharmaceutical formulations and material sciences.

Interesting facts

Interesting Facts about 5,7-Dimethoxy-3-(4-pyridyl)quinoline

5,7-Dimethoxy-3-(4-pyridyl)quinoline is a fascinating compound that belongs to the quinoline family, which is widely studied due to its significant biological and chemical properties. Here are some noteworthy aspects:

  • Biological Activity: This compound has been researched for its potential antimicrobial and anticancer properties, making it an important subject of study in medicinal chemistry.
  • Pharmacological Relevance: Its structure, featuring both quinoline and pyridine rings, suggests that it may interact with various biological targets, which enhances its therapeutic implications.
  • Synthesis: The synthesis of 5,7-dimethoxy-3-(4-pyridyl)quinoline involves intricate chemical reactions, including approaches like functional-group transformations and C-H activation, making it a common example in organic synthesis courses.
  • Structure-Activity Relationship (SAR): Scientists are keen on exploring the influence of the methoxy groups and the pyridyl substitution on the compound's biological activities, which plays a crucial role in drug design.

Overall, 5,7-dimethoxy-3-(4-pyridyl)quinoline is a prime example of how structural variations in organic compounds can lead to diverse functionalities and applications in pharmacology. As research continues, this compound may reveal even more secrets that contribute to key advancements in medicinal chemistry.

Synonyms
137206-97-4
5,7-Dimethoxy-3-(4-pyridinyl)quinoline
5,7-dimethoxy-3-pyridin-4-ylquinoline
5,7-dimethoxy-3-(pyridin-4-yl)quinoline
Quinoline, 5,7-dimethoxy-3-(4-pyridinyl)-
CHEMBL68423
5,7-Dmpq
Bio1_000429
Tocris-1222
5,7-Dimethoxy-3-pyridin-4-yl-quinoline
SCHEMBL3652915
DTXSID90160107
Bio1_000918
Bio1_001407
BDBM50039655
ICX5609220
NCGC00025053-01
DB-063190