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5,7-Dichloro-4-oxo-1H-quinoline-2-carboxylic acid

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Identification
Molecular formula
C10H4Cl2NO3
CAS number
84087-01-4
IUPAC name
5,7-dichloro-4-oxo-1H-quinoline-2-carboxylic acid
State
State

At room temperature, 5,7-dichloro-4-oxo-1H-quinoline-2-carboxylic acid is in a solid state, typically existing as a crystalline powder.

Melting point (Celsius)
280.00
Melting point (Kelvin)
553.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
286.05g/mol
Molar mass
286.0600g/mol
Density
1.7000g/cm3
Appearence

5,7-Dichloro-4-oxo-1H-quinoline-2-carboxylic acid typically appears as a yellow to orange crystalline solid. The crystalline structure is often distinct, with well-defined edges and formations.

Comment on solubility

Solubility of 5,7-Dichloro-4-oxo-1H-quinoline-2-carboxylic acid

The solubility of 5,7-dichloro-4-oxo-1H-quinoline-2-carboxylic acid (C10H4Cl2NO3) can be considered in the context of its molecular structure and functional groups. This compound contains a carboxylic acid group that typically enhances solubility in polar solvents due to its ability to form hydrogen bonds.

Key points regarding its solubility include:

  • The presence of the carboxylic acid functional group increases its affinity for water, suggesting good solubility in aqueous solutions.
  • However, the inclusion of chlorine atoms can introduce hydrophobic characteristics, which may affect overall solubility.
  • When assessing solubility, it is important to consider the pH of the solution, as ionization of the carboxylic acid can further influence solubility in water.

In summary, while 5,7-dichloro-4-oxo-1H-quinoline-2-carboxylic acid is expected to be more soluble in polar solvents, its precise solubility would need to be quantified experimentally. As the well-known adage goes, "Like dissolves like"; thus, this compound would likely not dissolve well in non-polar solvents.

Interesting facts

Interesting Facts About 5,7-Dichloro-4-oxo-1H-quinoline-2-carboxylic Acid

5,7-Dichloro-4-oxo-1H-quinoline-2-carboxylic acid is a fascinating compound that falls within the quinoline family, known for its diverse applications and biological properties. Here are some important points and intriguing facts about this compound:

  • Quinoline Derivative: The compound is a derivative of quinoline, which is a nitrogen-containing heterocyclic aromatic organic compound. Quinoline and its derivatives have been extensively studied for their antibacterial, antifungal, and anti-inflammatory activities.
  • Chlorine Atoms: The presence of two chlorine atoms (dihalo substitution) enhances the compound's biological activity. Chlorine is often employed in medicinal chemistry to improve the pharmacokinetic properties of pharmaceuticals.
  • Biological Activity: Compounds related to 5,7-dichloro-4-oxo-1H-quinoline-2-carboxylic acid have shown promise in *antimicrobial* and *antiviral* agents. This highlights the potential applicability of the compound in drug development.
  • Structure-Activity Relationship (SAR): Researchers often investigate the structure-activity relationship of such compounds to understand how changes in structure affect biological activity. The incorporation of various functional groups can significantly alter the compound's effects.
  • Research Applications: Its utility in research is notable, particularly in studying various biochemical pathways and mechanisms. It can also serve as a building block for synthesizing more complex molecules and pharmaceuticals.
  • Environmental Aspect: As with many synthetic compounds, understanding the environmental impact of 5,7-dichloro-4-oxo-1H-quinoline-2-carboxylic acid is crucial. Studies on its stability and degradation in environmental samples are essential to assess its ecological footprint.

In conclusion, the compound 5,7-dichloro-4-oxo-1H-quinoline-2-carboxylic acid is a promising subject of study due to its unique structure and potential applications in medicinal chemistry. Continuous research could unravel further insights into its properties and uses, making it a noteworthy compound in the field of chemistry.

Synonyms
5,7-Dichlorokynurenic acid
131123-76-7
5,7-DICHLORO-4-HYDROXYQUINOLINE-2-CARBOXYLIC ACID
5,7-Dcka
5,7-Dichloroquinurenic acid
5,7-Dichorokynurenic acid
2-Quinolinecarboxylic acid, 5,7-dichloro-4-hydroxy-
5,7-Dichloro-4-hydroxy-2-quinolinecarboxylic acid
5,7-dichloro-4-oxo-1H-quinoline-2-carboxylic acid
UNII-T61ORK73PY
T61ORK73PY
CHEMBL50267
DTXSID80893710
DCKA
1pbq
SR-01000075445
123158-59-8
Spectrum_001455
Tocris-0286
SpecPlus_000760
Lopac-D-138
Spectrum2_001999
Spectrum3_001736
Spectrum4_000085
Spectrum5_001096
Biomol-NT_000180
5,7-dichlorokynurenic-acid
5,7 Dichlorokynurenic Acid
Lopac0_000438
Oprea1_091974
BSPBio_003412
KBioGR_000350
KBioSS_001935
DivK1c_006856
SCHEMBL158714
SPECTRUM1502062
SPBio_002217
BPBio1_001172
GTPL2361
SCHEMBL8369562
Kynurenic acid, 5,7-dichloro-
KBio1_001800
KBio2_001935
KBio2_004503
KBio2_007071
KBio3_002632
DTXCID70872852
CHEBI:107660
GLXC-04703
HMS3261G18
HMS3266E21
HMS3411E03
HMS3675E03
Tox21_500438
BDBM50001266
CCG-39537
HB0078
MFCD00083173
PDSP1_000183
PDSP2_000182
AKOS012682248
AKOS015913821
DB01931
LP00438
SB69445
SDCCGSBI-0050423.P003
NCGC00015313-01
NCGC00015313-02
NCGC00015313-03
NCGC00015313-04
NCGC00015313-05
NCGC00015313-06
NCGC00015313-07
NCGC00015313-08
NCGC00015313-10
NCGC00024525-01
NCGC00024525-02
NCGC00024525-03
NCGC00024525-04
NCGC00024525-05
NCGC00024525-06
NCGC00261123-01
BS-20489
DA-20510
DCKA; 5,7-DICHLOROKYNURENIC ACID
PD002744
DB-062804
HY-100834
CS-0020477
EU-0100438
NS00070466
2-Quinolinecarboxylicacid,5,7-dichloro-4-hydroxy-
AE-641/14965124
5,7-Dichloro-4-hydroxy-quinoline-2-carboxylic acid
Q5204515
SR-01000075445-1
SR-01000075445-3
BRD-K60287130-001-03-2
BRD-K60287130-001-04-0
BRD-K60287130-001-05-7
5,7-Dichloro-4-hydroxy-quinoline-2-carboxylic acid anion
5,7-Dichloro-4-hydroxy-quinoline-2-carboxylic acid(DCKA)
5,7-Dichloro-4-oxo-1,4-dihydro-quinoline-2-carboxylic acid