Skip to main content

Aminopterin

ADVERTISEMENT
Identification
Molecular formula
C19H20N8O5
CAS number
54-62-6
IUPAC name
5,7-diamino-2,3-dihydrophthalazine-1,4-dione
State
State

The compound is a solid at room temperature.

Melting point (Celsius)
258.00
Melting point (Kelvin)
531.15
Boiling point (Celsius)
500.00
Boiling point (Kelvin)
773.15
General information
Molecular weight
440.44g/mol
Molar mass
440.4430g/mol
Density
2.0204g/cm3
Appearence

The compound appears as a yellow crystalline powder.

Comment on solubility

Solubility of 5,7-diamino-2,3-dihydrophthalazine-1,4-dione

5,7-diamino-2,3-dihydrophthalazine-1,4-dione (C19H20N8O5) exhibits noteworthy solubility characteristics that are crucial to understand for various pharmacological applications. Here are some key points regarding its solubility:

  • Organic Solvents: This compound is generally soluble in common organic solvents, which may include ethanol and methanol.
  • Aqueous Solubility: Its solubility in water is limited, likely due to the presence of multiple nitrogen atoms that can engage in hydrogen bonding, influencing overall interaction with water.
  • pH Dependence: The solubility may vary significantly with pH levels, with increased solubility often observed in more basic conditions due to deprotonation of amino groups.
  • Temperature Effects: Temperature can also play a role; increased temperatures may enhance solubility rates in solvents.

Understanding the solubility parameters of 5,7-diamino-2,3-dihydrophthalazine-1,4-dione is essential for its formulation and application, particularly in the field of medicinal chemistry. As one researcher aptly stated, "A compound's solubility can dictate not just its efficacy but also its stability and absorption in biological systems."


Interesting facts

Interesting Facts about 5,7-Diamino-2,3-dihydrophthalazine-1,4-dione

5,7-diamino-2,3-dihydrophthalazine-1,4-dione, sometimes referred to as a derivative of phthalazine, is a fascinating compound in the world of chemistry. Here are some captivating insights:

  • Pharmaceutical Potential: This compound is of interest in drug discovery and development, particularly due to its structural characteristics that may enable interactions with biological targets.
  • Research Applications: It is often the subject of academic research, exploring its properties and potential uses in various fields, including medicinal chemistry and biochemistry.
  • Analytical Chemistry: As a diverse molecule, 5,7-diamino-2,3-dihydrophthalazine-1,4-dione offers opportunities for chemists to develop new analytical techniques for studying complex reactions.
  • Synthetic Routes: Many synthetic pathways can lead to the creation of this compound, revealing insights into reaction mechanisms and guiding chemists in optimizing their methods.

As a student or researcher, one might say:

"Understanding the intricacies of 5,7-diamino-2,3-dihydrophthalazine-1,4-dione not only enhances our knowledge of phthalazine derivatives but also showcases the beauty of molecular diversity in organic chemistry."

In summary, 5,7-diamino-2,3-dihydrophthalazine-1,4-dione stands as a testament to the complexity and versatility of chemical compounds, continually inspiring exploration and innovation in scientific research.

Synonyms
3,5-diaminophthalhydrazide
5,7-diamino-2,3-dihydrophthalazine-1,4-dione
89977-59-3
1f3e
SCHEMBL4321648
DB04169
PD006913
NS00069461
Q27095004
5,7-diamino-1,2,3,4-tetrahydrophthalazine-1,4-dione