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Tetrahydrobiopterin

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Identification
Molecular formula
C9H15N5O3
CAS number
17528-72-6
IUPAC name
5,6,7,8-tetrahydropteridine
State
State

At room temperature, tetrahydrobiopterin is typically found as a solid substance. It needs careful handling to avoid degradation as it can oxidize when exposed to air.

Melting point (Celsius)
293.00
Melting point (Kelvin)
566.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
241.24g/mol
Molar mass
241.2430g/mol
Density
1.1200g/cm3
Appearence

Tetrahydrobiopterin is typically a colorless or white crystalline solid. It is hygroscopic and needs to be handled under controlled conditions to avoid moisture absorption.

Comment on solubility

Solubility of 5,6,7,8-tetrahydropteridine (C9H15N5O3)

5,6,7,8-Tetrahydropteridine is a unique compound known for its intriguing solubility characteristics. Its solubility in various solvents can be summarized as follows:

  • Water: 5,6,7,8-Tetrahydropteridine displays moderate solubility in water, making it accessible for numerous biological and chemical applications.
  • Organic Solvents: This compound is generally soluble in certain organic solvents such as methanol, ethanol, and dimethyl sulfoxide (DMSO), which enhances its utility in laboratory settings.
  • pH Sensitivity: The solubility of 5,6,7,8-tetrahydropteridine can vary with changes in pH; it is more soluble in acidic conditions compared to basic.

Due to its diverse solubility in polar and nonpolar environments, 5,6,7,8-tetrahydropteridine plays a significant role in various biochemical pathways. As a result, when studying this compound, it is essential to consider these solubility properties to optimize both synthesis and application processes. Remember, "solubility is a key to understanding reactivity and function."

Interesting facts

Interesting Facts about 5,6,7,8-Tetrahydropteridine

5,6,7,8-tetrahydropteridine is a fascinating compound that plays a crucial role in biological systems, particularly in the realm of biochemistry and medicine. Here are some compelling facts about this intriguing molecule:

  • Essential Co-Factor: This compound functions as a vital cofactor in various enzymatic reactions, including those involving amino acid synthesis. It's primarily involved in the production of neurotransmitters.
  • Role in Health: The compound is closely linked to the metabolism of folate, which is essential for DNA synthesis and repair. Deficiencies can lead to significant health issues, particularly related to cell division and growth.
  • Potential Therapeutics: Due to its biological importance, 5,6,7,8-tetrahydropteridine has been studied for its potential therapeutic applications, including the treatment of certain types of hereditary disorders such as phenylketonuria (PKU).
  • Metabolic Pathways: This molecule is integral to the biosynthesis of other important biochemical compounds, acting in pathways that regulate nitrogen metabolism in living organisms.
  • Research Frontiers: Ongoing research continues to explore its role in neurological functions and its implications in disorders like schizophrenia and Parkinson's disease, highlighting the compound's significance in mental health.

In conclusion, the compound 5,6,7,8-tetrahydropteridine represents a key player in various biological processes, making it a subject of ongoing interest for researchers aiming to uncover its full potential in health and disease.

Synonyms
5,6,7,8-tetrahydropteridine
tetrahydropteridine
10593-78-9
H4-biopterin
Pteridine, 5,6,7,8-tetrahydro-
5,6,7,8-tetrahydro-Pteridine
CHEBI:28889
DTXSID00147429
343269-86-3
Pteridine, 5,6,7,8-tetrahydro- (6CI,7CI,8CI,9CI)
SCHEMBL1448583
DTXCID9069920
SCHEMBL20565496
KAA59378
AKOS006279616
PTERIDINE, 1,5,6,7-TETRAHYDRO-
DB-278021
NS00122173
C05650
EN300-128317
Q27103945