Thiomethyluracil (2-Thiouracil) | Solubility of Things

Identification

Molecular formula

C₈H₁₂N₂O₂S

CAS number

141-90-2

IUPAC name

5,5-diethyl-2-sulfanyl-1H-pyrimidine-4,6-dione

State

At room temperature, Thiomethyluracil is a solid substance. It remains stable under normal conditions, making it a suitable compound for laboratory use and storage.

Melting point (Celsius)

213.00

Melting point (Kelvin)

486.15

Boiling point (Celsius)

325.00

Boiling point (Kelvin)

598.15

General information

Molecular weight

156.21g/mol

Molar mass

156.2060g/mol

Density

1.2760g/cm³

Appearence

Thiomethyluracil, also known as 2-Thiouracil, typically appears as a white to off-white crystalline powder. Its solid form is notably similar to other uracil derivatives, providing it with a suitable crystalline structure essential for its functional applications in various biochemical processes.

Comment on solubility

Solubility of 5,5-Diethyl-2-sulfanyl-1H-pyrimidine-4,6-dione

The solubility of 5,5-diethyl-2-sulfanyl-1H-pyrimidine-4,6-dione in various solvents can be quite intriguing. This compound possesses multiple functional groups that influence its interactions with solvents, affecting its solubility in a variety of environments. Here are some key points to consider:

Polar Solvents: The presence of the sulfanyl group may enhance solubility in polar solvents such as water and alcohols. This feature is often due to hydrogen bonding capabilities.
Non-Polar Solvents: Conversely, the diethyl groups suggest some degree of hydrophobic character, which may limit solubility in non-polar solvents; however, it could still exhibit limited solubility depending on the solvent structure.
Temperature Effects: Solubility can also be temperature-dependent, with higher temperatures usually increasing the solubility of many organic compounds.

In summary, while 5,5-diethyl-2-sulfanyl-1H-pyrimidine-4,6-dione can demonstrate varying solubility in different solvents, the exact nature and extent of its solubility require careful empirical investigation to fully elucidate its behavior in various chemical environments. As one might say, “The solvent determines the solution!”

Interesting facts

Interesting Facts about 5,5-Diethyl-2-sulfanyl-1H-pyrimidine-4,6-dione

5,5-Diethyl-2-sulfanyl-1H-pyrimidine-4,6-dione is a fascinating compound not only for its unique structure but also for its versatility in various chemical applications. Here are several noteworthy aspects of this intriguing molecule:

Structural Diversity: This compound features a pyrimidine ring, which is a fundamental building block in both organic and medicinal chemistry. The presence of both diethyl groups and a sulfanyl group contributes to its chemical diversity.
Biological Significance: Pyrimidine derivatives, including this compound, are often explored for their biological activities. They may exhibit potential pharmacological properties, making them candidates for drug discovery.
Synthesis Insight: The synthesis of 5,5-diethyl-2-sulfanyl-1H-pyrimidine-4,6-dione can involve various reaction pathways, such as condensation reactions. Understanding these pathways is crucial for researchers aiming to modify its structure for specific applications.
Reactivity Potential: The functional groups present in this compound give it a reactivity profile that may be exploited in further chemical reactions, showcasing its utility in synthetic organic chemistry.
Research and Development: Ongoing research into this and similar compounds continues to reveal more about their properties and potential applications, from agriculture to pharmaceuticals.

In summary, 5,5-diethyl-2-sulfanyl-1H-pyrimidine-4,6-dione is not just a simple chemical; it is a compound of significant interest in various fields. Its potential roles in drug design and synthesis make it a worthy subject of study for chemists and researchers alike. As stated, "The most profound truths are often found in the simplest of structures."