Skip to main content

Barbital

ADVERTISEMENT
Identification
Molecular formula
C8H12N2O3
CAS number
57-44-3
IUPAC name
5,5-diethyl-1-methyl-hexahydropyrimidine-2,4,6-trione
State
State

At room temperature, Barbital is in a solid state.

Melting point (Celsius)
190.50
Melting point (Kelvin)
463.65
Boiling point (Celsius)
465.00
Boiling point (Kelvin)
738.15
General information
Molecular weight
184.19g/mol
Molar mass
184.1930g/mol
Density
1.1400g/cm3
Appearence

Barbital is a white, crystalline powder. It may appear as colorless crystals or a white crystalline solid.

Comment on solubility

Solubility of 5,5-Diethyl-1-methyl-hexahydropyrimidine-2,4,6-trione

When discussing the solubility of 5,5-diethyl-1-methyl-hexahydropyrimidine-2,4,6-trione (C8H12N2O3), several factors come into play:

  • Polarity of the Compound: This compound contains both nitrogen and oxygen atoms, which can lead to polar characteristics. Hence, it may exhibit variable solubility in polar solvents.
  • Solvent Interaction: Its ability to dissolve in polar solvents like water may be significant, but non-polar solvents could also facilitate solubility depending on the specific intermolecular forces.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the presence of the nitrogen and oxygen can enhance solubility in suitable solvents.

As a rule of thumb, *like dissolves like* — so, compounds of similar polarity often dissolve well together. In practical terms, if you were to experiment with the solubility of this compound:

  1. Try dissolving in water, as the polar environment can help explore its limits.
  2. Consider other solvents like ethanol or methanol for comparison.
  3. Take note of temperature and stirring, as these can significantly affect solubility rates.

In conclusion, the solubility of 5,5-diethyl-1-methyl-hexahydropyrimidine-2,4,6-trione is likely influenced by its chemical structure and external conditions. Always ensure thorough experimentation to ascertain its precise solubility profile.

Interesting facts

Interesting Facts about 5,5-Diethyl-1-methyl-hexahydropyrimidine-2,4,6-trione

5,5-Diethyl-1-methyl-hexahydropyrimidine-2,4,6-trione, a fascinating compound, showcases a unique structure that has captured the interest of chemists and researchers alike. Here are some intriguing aspects:

  • Structure Complexity: This compound belongs to the pyrimidine family, characterized by its hexahydropyrimidine core. The presence of multiple ethyl groups and a methyl group contributes to its distinctive characteristics and functionality.
  • Reactivity: The three carbonyl groups present in the compound make it an interesting target for chemical reactions, particularly for synthesis in medicinal chemistry. These groups are known for their ability to engage in reactions that can yield various derivatives.
  • Biological Relevance: Compounds like this one have been studied for their potential biological activities. Research indicates that derivatives of pyrimidine structures can exhibit antiviral and anticancer properties, making them valuable in drug discovery.
  • Versatile Applications: Beyond medicinal chemistry, this compound's derivatives are explored in material science and organic synthesis. The reactivity of the carbonyls allows for numerous synthetic pathways, paving the way for further innovation.

As a scientist or student delving into organic synthesis, understanding compounds like 5,5-diethyl-1-methyl-hexahydropyrimidine-2,4,6-trione not only enriches our knowledge of organic molecules but also opens doors to new research and development opportunities. The interplay of its structural features and reactivity certainly represents a colorful puzzle in the vast landscape of chemistry.

Synonyms
metharbital
Metharbitone
Methylbarbital
Gemonil
Metabarbital
N-Methylbarbital
Endiemalum
Metharbutal
50-11-3
1-Methylbarbital
Methabarbital
Endiemal
Metarbital
Sch 412
5,5-Diethyl-1-methylbarbituric acid
Metharbitalum
Metarbitale
Gemonit
AN 23
Metarbital [INN-Spanish]
Metharbitalum [INN-Latin]
5,5-diethyl-1-methyl-1,3-diazinane-2,4,6-trione
Metharbital ciii
NSC 27156
Barbituric acid, 5,5-diethyl-1-methyl-
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5,5-diethyl-1-methyl-
EINECS 200-011-2
NSC-27156
UNII-02OS7K758T
BRN 0184688
DTXSID6023280
02OS7K758T
5,5-Diethyl-1-methyl-2,4,6(1H,3H,5H)-pyrimidinetrione
5,5-diethyl-1-methylpyrimidine-2,4,6(1H,3H,5H)-trione
DTXCID103280
Methabarbitone
Metarbitale [DCIT]
Metharbital [USP:INN:BAN:JAN]
5-24-09-00144 (Beilstein Handbook Reference)
METHARBITAL CIII (200 MG)
NCGC00181148-01
Metarbital (INN-Spanish)
Metharbitalum (INN-Latin)
METHARBITAL (MART.)
METHARBITAL [MART.]
Metharbital (USP:INN:BAN:JAN)
Gemonil (TN)
Methylbarbital (1.0mg/ml in Acetonitrile)
Metharbital (JAN/INN)
methobarbitone
METHARBITAL [MI]
METHARBITAL [INN]
METHARBITAL [JAN]
CHEMBL450
METHARBITAL [VANDF]
SCHEMBL78867
METHARBITAL [WHO-DD]
GTPL7230
SCHEMBL22556220
CHEBI:31827
METHARBITAL [ORANGE BOOK]
N03AA30
AAA05011
Metharbital 1.0 mg/ml in Methanol
NSC27156
Tox21_112752
Barbituric acid,5-diethyl-1-methyl-
1-Methyl-5,5-diethyl barbituric acid
AKOS006239548
WLN: T6VMVNV FHJ D1 F2 F2
DB00463
CAS-50-11-3
NS00016843
D01382
Q1176294
BRD-K88143662-001-01-5
5,5-Diethyl-1-methyl-2,4,6-trioxo-hexahydropyrimidine
2,6(1H,3H,5H)-Pyrimidinetrione, 5,5-diethyl-1-methyl-
5,5-Diethyl-1-methyl-2,4,6(1H,3H,5H)-pyrimidinetrione #
pyrimidine-2,4,6(1H,3H,5H)-trione, 5,5-diethyl-1-methyl-
5,5-diethyl-6-hydroxy-3-methyl-2,3,4,5-tetrahydropyrimidine-2,4-dione
200-011-2
VOK