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5-Oxo-ETE

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Identification
Molecular formula
C20H28O3
CAS number
251167-22-1
IUPAC name
5-oxoicosa-6,8,11,14-tetraenoic acid
State
State

At room temperature, 5-Oxo-ETE is typically in a liquid state due to its fatty acid structure.

Melting point (Celsius)
28.00
Melting point (Kelvin)
301.15
Boiling point (Celsius)
258.00
Boiling point (Kelvin)
531.15
General information
Molecular weight
316.45g/mol
Molar mass
316.4670g/mol
Density
0.8954g/cm3
Appearence

Appearance: 5-Oxo-ETE is typically a pale yellow to amber colored oil. It may also appear as a viscous liquid depending on its concentration and purity.

Comment on solubility

Solubility of 5-oxoicosa-6,8,11,14-tetraenoic acid

The solubility of 5-oxoicosa-6,8,11,14-tetraenoic acid (C20H28O3) presents quite an interesting challenge due to its unique structure. This compound is a polyunsaturated fatty acid, which typically exhibits a range of solubility properties based on the following factors:

  • Polarity: The presence of the carboxylic acid group (–COOH) makes the molecule polar, potentially increasing its solubility in polar solvents like water.
  • Hydrophobic regions: Despite having a polar end, the long hydrocarbon chain tends to be hydrophobic, suggesting limited water solubility.
  • Temperature: Solubility can often increase with temperature, allowing for greater dissolution in organic solvents at elevated temperatures.
  • Solvent compatibility: 5-oxoicosa-6,8,11,14-tetraenoic acid is likely to be more soluble in organic solvents such as ethanol or acetone compared to water.

To sum up, the solubility of this compound is possibly modest in water while being significantly more favorable in organic solvents. Experimentation would be necessary to ascertain exact solubility characteristics in various environments. Understanding these solubility traits is crucial for various applications, especially in biochemical contexts.

Interesting facts

Interesting Facts about 5-Oxoicosa-6,8,11,14-tetraenoic Acid

5-Oxoicosa-6,8,11,14-tetraenoic acid, often abbreviated as 5-oxo-ETE, is a fascinating compound in the realm of biochemistry and pharmacology. This fatty acid derivative plays a significant role in various physiological processes and is studied for its potential therapeutic applications. Here are some intriguing aspects about this compound:

  • Origin: 5-Oxoicosa-6,8,11,14-tetraenoic acid is derived from arachidonic acid, a polyunsaturated fatty acid that is a key component of cellular membranes and a precursor to biologically active compounds.
  • Biological Significance: It is known to influence inflammatory responses and is involved in signaling pathways that regulate cell growth and differentiation.
  • Enzymatic Conversion: The compound is produced through the action of lipoxygenases, which catalyze the oxidation of polyunsaturated fatty acids. This enzymatic pathway underscores the importance of fatty acids in cellular signaling.
  • Research Potential: Scientists are investigating the use of 5-oxo-ETE in developing new anti-inflammatory and analgesic medications, as its unique structure may offer selective therapeutic benefits.
  • Natural Sources: While primarily studied in the context of human biochemistry, similar compounds can also be found in certain plant oils and marine organisms, showcasing the diversity of fatty acids in nature.

In summary, 5-oxoicosa-6,8,11,14-tetraenoic acid is not just another fatty acid; it represents a bridge between basic biochemical research and clinical applications. As noted by researchers, “Understanding the role of these metabolites offers insights into the intricate balance of health and disease.” Exploring such compounds can lead to breakthroughs in how we approach treatments for inflammation and other related conditions.

Synonyms
5-Oxoete
5-oxoicosa-6,8,11,14-tetraenoic acid
5-Kete
126432-17-5
106154-18-1
ETE-5-Oxo
6,8,11,14-Eicosatetraenoicacid, 5-oxo-
CBiol_001863
KBioGR_000173
KBioSS_000173
KBio2_000173
KBio2_002741
KBio2_005309
KBio3_000345
KBio3_000346
Bio1_000149
Bio1_000638
Bio1_001127
Bio2_000173
Bio2_000653
DTXSID101288286
BCP31371
5-KETE;5-Oxoete;5-oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid;5-Oxo-eicosatetraenoic acid