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5-Nitrothiazol-2-amine

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Identification
Molecular formula
C3H3N3O2S
CAS number
19339-46-5
IUPAC name
5-nitrothiazol-2-amine
State
State

At room temperature, 5-nitrothiazol-2-amine is typically encountered as a solid. It remains stable in solid form under standard laboratory conditions, making it easy to handle during storage and experimentation.

Melting point (Celsius)
151.00
Melting point (Kelvin)
424.15
Boiling point (Celsius)
311.00
Boiling point (Kelvin)
584.15
General information
Molecular weight
145.15g/mol
Molar mass
145.1470g/mol
Density
1.6830g/cm3
Appearence

5-Nitrothiazol-2-amine is a yellow crystalline solid, which is often utilized in chemical research and synthesis due to its distinct properties. It is visually identifiable by its characteristic yellow coloration and crystalline structure.

Comment on solubility

Solubility of 5-nitrothiazol-2-amine

5-nitrothiazol-2-amine, a compound with interesting chemical properties, exhibits solubility characteristics that are worth noting. The solubility of this compound can be affected by several factors, including:

  • Polarity: Due to the presence of both nitro and amine functional groups, the compound demonstrates a degree of polarity which often contributes to its solubility in polar solvents like water.
  • Temperature: Typically, an increase in temperature can lead to an increase in solubility, allowing for more of the compound to dissolve in a given solvent.
  • pH Levels: The solubility can also vary with changes in pH. For amines, basic conditions may enhance solubility due to protonation, while acidic conditions could affect solubility differently.

In general, the solubility of 5-nitrothiazol-2-amine is moderate. It tends to be more soluble in organic solvents compared to water, which may limit its applications in aqueous environments. Understanding these factors is crucial for its use in various chemical processes and formulations.

As stated in numerous studies, "The solubility of compounds often dictates their reactivity and utility in chemical synthesis." Thus, when working with 5-nitrothiazol-2-amine, it is essential to consider these solubility influences to optimize its use in practical applications.

Interesting facts

Interesting Facts About 5-Nitrothiazol-2-amine

5-Nitrothiazol-2-amine is a fascinating compound that stands out in the realm of chemistries due to its unique structure and functional properties. It is a member of the thiazole family, which boasts a variety of applications in medicinal chemistry and agricultural sciences. Here are some intriguing points to consider:

  • Pharmacological Relevance: This compound is known for its bioactive properties, making it an important candidate for drug development. Its structure allows for interactions with biological targets, which can lead to the synthesis of novel pharmaceuticals.
  • Antimicrobial Activity: 5-Nitrothiazol-2-amine has demonstrated promising antimicrobial effects, potentially paving the way for the discovery of new antibiotics. Such compounds are essential in addressing antibiotic resistance issues that are prevalent in modern medicine.
  • Environmental Applications: Beyond its medicinal uses, this compound can play a role in environmental chemistry. Its derivatives have been studied for their capacity to degrade pollutants, showcasing the versatility of heterocyclic compounds.
  • Synthetic Pathways: The synthesis of 5-nitrothiazol-2-amine involves specific reactions that highlight the importance of nitro groups in enhancing reactivity and selectivity in organic synthesis.

As a student or professional in the field of chemistry, understanding compounds like 5-nitrothiazol-2-amine can inspire innovative approaches in drug discovery and environmental remediation. Each discovery contributes to a broader understanding of chemical interactions, potentially leading to breakthroughs in science and technology.

In summary, 5-nitrothiazol-2-amine serves as a prime example of how a simple chemical structure can yield significant implications in various scientific fields, illustrating the comprehensive nature of chemistry.

Synonyms
2-AMINO-5-NITROTHIAZOLE
121-66-4
5-Nitrothiazol-2-amine
Enheptin
5-Nitro-1,3-thiazol-2-amine
Entramin
Nitramin IDO
Amnizol soluble
Enheptin-T
5-Nitro-2-thiazolamine
2-Thiazolamine, 5-nitro-
Enheptin premix
Aminonitrothiazole
2-amino-5-nitro-1,3-thiazole
Enheptyne
Aminzol soluble
Thiazole, 2-amino-5-nitro-
5-Nitro-2-thiazolylamine
Enheptin T
5-Nitro-2-aminothiazole
USAF EK-6561
Nitromin ido
NCI-C03065
5-nitro-thiazol-2-ylamine
CCRIS 37
NSC 4
U 7458
HSDB 4022
EINECS 204-490-9
NSC-4
UNII-1GR77A37Z5
BRN 0126797
DTXSID6020066
AI3-50030
AMINONITROTHIAZOL
1GR77A37Z5
2-amino-5-nitrothiazol
NSC4
MFCD00005326
DTXCID8066
CHEBI:82386
4-27-00-04675 (Beilstein Handbook Reference)
Enheptin (VAN)
5-Nitrothiazol-2-ylamine
Aminonitrothiazolum
2-AMINO-5-NITROTHIAZOLE (IARC)
2-AMINO-5-NITROTHIAZOLE [IARC]
CAS-121-66-4
entramine
Hexamor
2-amino-5-nitro-thiazol
2-amino 5-nitro thiazole
Oprea1_237935
MLS002152868
SCHEMBL375929
WLN: T5N CSJ BZ DNW
CHEMBL408049
2-AMINO-4-NITROTHIAZOLE
SCHEMBL19435597
2-Amino-5-nitrothiazole, 97%
5-Nitro-1,3-thiazol-2-amine #
ALBB-021308
STR02181
Tox21_202377
Tox21_303575
STK317992
AKOS000120496
2-AMINO-5-NITROTHIAZOLE [MI]
AC-2989
PS-3292
SB31744
s12411
2-AMINO-5-NITROTHIAZOLE [HSDB]
NCGC00091644-01
NCGC00091644-02
NCGC00257304-01
NCGC00259926-01
BP-10109
SMR001224487
DB-000135
A0381
CS-0030564
NS00002376
U7458
EN300-16819
C19324
A804773
Q27155915
Z56786623
F0001-0347
InChI=1/C3H3N3O2S/c4-3-5-1-2(9-3)6(7)8/h1H,(H2,4,5
204-490-9