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PD-166326

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Identification
Molecular formula
C19H20N5O3
CAS number
194423-17-3
IUPAC name
5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazolin-3-ium-2,4-diamine
State
State

At room temperature, PD-166326 is most commonly found in a solid state. This compound, often used in research contexts, is stable and typically requires specific handling due to its state and properties.

Melting point (Celsius)
221.00
Melting point (Kelvin)
494.15
Boiling point (Celsius)
470.00
Boiling point (Kelvin)
743.15
General information
Molecular weight
409.48g/mol
Molar mass
409.4770g/mol
Density
1.3810g/cm3
Appearence

PD-166326 typically appears as a crystalline solid that is pale yellow to brown in coloration. It may also appear in a more refined powdered form, which shares this color profile.

Comment on solubility

Solubility of 5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazolin-3-ium-2,4-diamine

The solubility of the compound 5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazolin-3-ium-2,4-diamine (C19H20N5O3) is influenced by various factors, primarily its chemical structure. Being a complex organic compound with multiple functional groups, its solubility can vary significantly in different solvents. Here are some key points to consider:

  • Polarity: The presence of both hydrophobic and hydrophilic regions in the molecule suggests it may exhibit differing solubility in polar and non-polar solvents.
  • Solvent Effects: It is likely to have enhanced solubility in polar protic solvents such as water or alcohols due to hydrogen bonding capabilities.
  • Functional Groups: The trimethoxy and quinazoline moieties can contribute to interactions with the solvent, systematically influencing its dissolution behavior.
  • pH Sensitivity: Given that the compound is a salt (indicated by the 'ium' suffix), its solubility might also be sensitive to pH changes, potentially increasing in acidic conditions.
  • Temperature Dependence: Elevated temperatures may enhance solubility via increased molecular motion, thus favoring dissolution.

In summary, the solubility of 5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazolin-3-ium-2,4-diamine is a complex interplay of its structural features and the properties of the solvent. To truly understand its solubility profile, experimental data in various solvents and conditions would be necessary.

Interesting facts

Interesting Facts about 5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazolin-3-ium-2,4-diamine

The compound 5-methyl-6-[(3,4,5-trimethoxyanilino)methyl]quinazolin-3-ium-2,4-diamine holds significant interest in the field of medicinal chemistry due to its potential therapeutic applications. Here are some fascinating aspects of this compound:

  • Quinazoline Derivative: This compound belongs to the quinazoline family, which is known for its diverse biological activities, including anti-cancer, anti-inflammatory, and anti-viral properties.
  • Structure Complexity: The molecule showcases a unique structure that incorporates a quinazolin-3-ium core, which is widely studied for its electronic properties and interaction with biological molecules.
  • Functional Groups: Notably, the presence of the 3,4,5-trimethoxyaniline moiety suggests potential for interaction with various receptors and pathways, making it a candidate for further investigation in pharmacology and drug design.
  • Synthesis Pathways: The synthesis of such complex organic compounds often requires innovative synthetic strategies, including multi-step reactions that highlight the ingenuity of organic chemists.
  • Research Potential: Studies have shown that compounds with quinazoline structures can exhibit a range of pharmacological effects, stimulating ongoing research to fully understand their mechanisms of action and clinical potential.

This compound exemplifies how organic chemistry intertwines with medicinal research, presenting rich opportunities for discovery and development of new therapeutic agents. As research continues, compounds like this may aid in the advancement of treatments for various diseases.

Synonyms
2,4-diamino-5-methyl-6-{[(3,4,5-trimethoxyphenyl)amino]methyl}quinazolin-1-ium