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Zolpidem

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Identification
Molecular formula
C19H21N3O
CAS number
82626-48-0
IUPAC name
5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one
State
State

At room temperature, zolpidem is typically in the form of a solid, specifically a crystalline powder.

Melting point (Celsius)
238.00
Melting point (Kelvin)
511.00
Boiling point (Celsius)
703.80
Boiling point (Kelvin)
977.00
General information
Molecular weight
307.39g/mol
Molar mass
307.3910g/mol
Density
1.1500g/cm3
Appearence

Zolpidem is typically found in the form of a crystalline powder that is white to off-white in color.

Comment on solubility

Solubility of 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one

The compound 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one, with the chemical formula C19H21N3O, exhibits intriguing solubility characteristics that are vital for its practical applications.

Key Aspects of Solubility:

  • Polar vs. Nonpolar: This compound's structure indicates a balance between polar and nonpolar characteristics, suggesting that it may possess moderate solubility in both polar solvents (like water) and nonpolar solvents (such as organic solvents).
  • Hydrogen Bonding: The presence of nitrogen and oxygen atoms in the molecule can facilitate hydrogen bonding, enhancing its solubility in water compared to less polar solvents.
  • Molecular Size: At a relatively high molecular weight of 319.4 g/mol, solubility may be affected. Generally, larger molecules tend to be less soluble.
  • Saturation Limits: When dissolved, factors such as temperature and the solvent's ionic strength may further influence its saturation limits, making these conditions critical for dissolving the compound.

In conclusion, while detailed quantitative solubility values for 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one are not extensively documented, an understanding of its molecular structure and properties can provide insights into its expected behavior in various solvents. Experimentally determining its solubility in different media will be essential for applications in pharmaceuticals and chemical research.

Interesting facts

Interesting Facts about 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one

5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one is a fascinating compound with a structural framework that incorporates various biologically relevant motifs. Explore some of the intriguing aspects of this compound:

  • Multifunctional Potential: This compound contains both a pyrido and an imidazole unit which are often found in natural products and medicinal chemistry, hinting at a range of potential biological activities.
  • Medicinal Chemistry: Its specific arrangement of nitrogen-containing heterocycles suggests that it may exhibit interesting pharmacological properties. Compounds similar to this structure have been explored for their anticancer, antimicrobial, and anti-inflammatory effects.
  • Synthetic Challenges: The synthesis of such complex compounds often requires advanced techniques in organic chemistry, such as multi-step synthesis and the use of protecting groups, showcasing the ingenuity required in modern chemical synthesis.
  • Research Applications: The exploration of derivatives of this structure could lead to the development of novel therapeutic agents. Scientists are continually investigating relationships between structure and activity to optimize efficacy and reduce side effects.
  • Framework Diversity: The presence of both indole and pyridine-type systems contributes to the rich chemical behavior of this compound, with implications for studying electron transfer and reactivity.

As compounds like 5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one are further understood, they may reveal essential insights into drug design and the treatment of various diseases. In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have a lot of ideas." Embrace the innovative spirit as we delve deeper into this captivating world of chemical compounds!

Synonyms
alosetron
122852-42-0
Lotronex
GR68755
CHEBI:253342
Alosetron (INN)
UNII-13Z9HTH115
A03AE01
13Z9HTH115
1H-Pyrido(4,3-b)indol-1-one, 2,3,4,5-tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-
2,3,4,5-Tetrahydro-5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-1H-pyrido(4,3-b)indol-1-one
5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one
GR 68755
DTXSID6044278
ALOSETRON [INN]
Alosetron [INN:BAN]
MLS001401464
5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H,2H,3H,4H,5H-pyrido[4,3-b]indol-1-one
5-Methyl-2-[(4-methyl-1H-imidazol-5-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one
5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-1-one
NCGC00167528-01
SMR000469211
alosetronum
2,3,4,5-Tetrahydro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H-pyrido[4,3-b]indol-1-one
5-methyl-2-((5-methyl-1H-imidazol-4-yl)methyl)-2,3,4,5-tetrahydro-1H-pyrido(4,3-b)indol-1-one
5-methyl-2-((5-methyl-1h-imidazol-4-yl)methyl)-2,3,4,5-tetrahydro-1h-pyrido[4,3-b]indol-1-one
ALOSETRON [MI]
ALOSETRON [VANDF]
SCHEMBL631
ALOSETRON [WHO-DD]
CHEMBL1110
cid_60758
GTPL2296
DTXCID4024278
BDBM93624
HMS3745K07
BCP14060
BDBM50014558
HY-70050A
AKOS027427023
CS-0640
DB00969
FA43705
AS-83859
NS00070901
D07129
AB00698548-07
EN300-18563823
Q416463
BRD-K46742498-003-11-0
5-Methyl-2-(5-methyl-1H-imidazol-4-ylmethyl)-2,3,4,5-tetrahydro-pyrido[4,3-b]indol-1-one
5-methyl-2-[(4-methyl-1~{H}-imidazol-5-yl)methyl]-3,4-dihydropyrido[4,3-b]indol-1-one
2,3,4,5-tetrahydro-5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-1H-pyrido[4,3-b]indol-1one
5-Methyl-2-(5-methyl-3H-imidazol-4-ylmethyl)-2,3,4,5-tetrahydro-pyrido[4,3-b]indol-1-one hydrochloride
5-methyl-2-[(5-methyl-1H-imidazol-4-yl)methyl]-3,4-dihydropyrid[4,3-b]indol-1-one;hydrochloride