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Tazobactam

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Identification
Molecular formula
C10H12N4O5S1
CAS number
89786-04-9
IUPAC name
5-methyl-2-[2-oxo-1-[[2-(2-thienyl)acetyl]amino]ethyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
State
State

At room temperature, Tazobactam is in a solid state.

Melting point (Celsius)
171.00
Melting point (Kelvin)
444.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
322.34g/mol
Molar mass
322.3430g/mol
Density
1.7200g/cm3
Appearence

Tazobactam typically appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 5-Methyl-2-[2-oxo-1-[[2-(2-thienyl)acetyl]amino]ethyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid

The solubility of the compound 5-methyl-2-[2-oxo-1-[[2-(2-thienyl)acetyl]amino]ethyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, with the chemical formula C10H12N4O5S1, can be influenced by several factors including its molecular structure and functional groups. Understanding its solubility is crucial for various applications, particularly in pharmaceuticals and organic synthesis.

Key Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups, such as carboxylic acids and amides, often increases solubility in polar solvents like water.
  • Hydrogen Bonding: Compounds capable of forming hydrogen bonds with solvents typically exhibit enhanced solubility.
  • Molecular Size: Smaller molecular size generally correlates with higher solubility, while larger or more complex structures may hinder dissolving.
  • pH Levels: The solubility of acidic or basic compounds can vary significantly with pH, affecting ionization and interactions with solvent molecules.

In this specific case, the thiazine structure, along with the carboxylic acid moiety, suggests that the compound may possess some degree of aqueous solubility, especially under acidic conditions that can facilitate protonation and enhance interactions with water. Additionally, the thienyl group could also contribute to solubility in organic solvents due to its hydrophobic nature, creating a balance between solubility in polar and non-polar environments.

To summarize, while definitive solubility data may not be extensively documented for this compound, it is likely to have varied solubility characteristics based on the aforementioned factors. Experimentation and characterization in both polar and non-polar solvents would provide more comprehensive insights into its solubility profile.

Interesting facts

Exploring 5-methyl-2-[2-oxo-1-[[2-(2-thienyl)acetyl]amino]ethyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid

This compound, known for its complex structure and intriguing properties, is a noteworthy example within the realm of organic chemistry. Here are some fascinating insights about this chemical:

  • Structural Complexity: The molecule features a unique thiazine ring, which is a six-membered ring that contains both sulfur and nitrogen. This structure contributes to its biological activity.
  • Pharmacological Potential: Compounds like this one are often investigated for their potential medicinal properties. The presence of the thienyl and carboxylic acid groups may imply activity against various biological targets.
  • Versatile Functional Groups: The compound includes several functional groups such as amides and ketones, which often enhance reactivity and biological interactions in drug design.
  • Thienyl Impact: The thienyl substituent is significant in drug development. Thiophene derivatives frequently exhibit interesting electronic and chemical properties, providing avenues for unique therapeutic applications.
  • Research Interest: Ongoing studies involving this compound may focus on its synthesis, optimization, and potential as a lead compound in medicinal chemistry.

In summary, the 5-methyl-2-[2-oxo-1-[[2-(2-thienyl)acetyl]amino]ethyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid stands as a testament to the complexities of organic compounds and their importance in the search for novel pharmaceuticals. As a scientist, delving into its properties and applications may yield exciting discoveries in the field of chemistry.