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5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile

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Identification
Molecular formula
C15H10N4O
CAS number
151485-33-1
IUPAC name
5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile
State
State

The substance is in a solid state at room temperature, often available as a crystalline powder.

Melting point (Celsius)
214.00
Melting point (Kelvin)
487.20
Boiling point (Celsius)
433.30
Boiling point (Kelvin)
706.50
General information
Molecular weight
263.27g/mol
Molar mass
263.2740g/mol
Density
1.3560g/cm3
Appearence

The compound appears as an off-white to pale yellow powder at room temperature.

Comment on solubility

Solubility of 5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile

The solubility of the compound 5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile (C15H10N4O) can be influenced by several factors. Its overall structure, which includes a pyridine ring and functional groups, plays a crucial role in determining how well it dissolves in various solvents.

General Solubility Characteristics:

  • Polarity: The presence of polar functional groups often enhances the solubility in polar solvents like water, while non-polar regions may favor organic solvents.
  • Hydrogen Bonding: Capable of forming hydrogen bonds; this can significantly increase solubility in suitable solvents.
  • Temperature: Increasing temperature usually enhances solubility; however, specific compounds may behave differently.
  • pH Dependence: The solubility can vary with pH, particularly for compounds with acidic or basic functional groups.

In general, qualitative assessments suggest that 5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile may exhibit moderate solubility in a variety of organic solvents. However, experimental solubility data should be consulted for precise applications, as the actual solubility will depend greatly on the solvent and environmental conditions.

Interesting facts

Interesting Facts about 5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile

5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile is a fascinating compound that intersects several important fields of research. Here are some intriguing aspects:

  • Structure and Complexity: This compound showcases a complex molecular structure featuring a fusion of imidazole and pyridine rings. Such *multi-ring systems* are often found in biologically active molecules, which makes this compound notable for pharmacological studies.
  • Biological Relevance: Compounds like 5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile are often investigated for their potential *antimicrobial*, *antitumor*, and *anti-inflammatory* properties. The unique chemical functionalities may interact with biological systems in intriguing ways.
  • Synthetic Opportunities: The synthesis of this compound can open pathways for chemists to develop new *therapeutics*. The diversity of substituents on the pyridine and imidazole rings allows for considerable variability in *mechanistic pathways* and *target affinity*.
  • Research Applications: Its structure may provide insights into the design of *selective inhibitors* for various enzyme targets. Given the *ubiquitous role* of pyridine-based molecules in medicinal chemistry, this compound holds promise for future drug development.
  • Structural Studies: Understanding the conformational properties of 5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile through methods like X-ray crystallography or NMR spectroscopy can enhance our knowledge of how such structures influence biological activity.

The *exploration of this compound* not only contributes to our understanding of complex organic structures but may also pave the way for discovering new therapeutic agents, making it a subject worth investigating further in both academic and applied chemistry contexts.

Synonyms
Olprinone
106730-54-5
loprinone
Olprinone [INN]
5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile
olprinona
4Y8BMI9YGC
Olprinone (INN)
LOPRINONE [MI]
UNII-4Y8BMI9YGC
OLPRINONE [WHO-DD]
DTXSID1048461
1,2-Dihydro-5-imidazo(1,2-alpha)pyridin-6-yl-6-methyl-2-oxonicotinonitrile
3-Pyridinecarbonitrile,1,2-dihydro-5-imidazo[1,2-a]pyridin-6-yl-6-methyl-2-oxo-
1,2-DIHYDRO-5-IMIDAZO(1,2-.ALPHA.)PYRIDIN-6-YL-6-METHYL-2-OXONICOTINONITRILE
5-(Imidazo[1,2-a]pyridin-6-yl)-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
olprinonum
5-imidazo(1,2-a)pyridin-6-yl-6-methyl-2-oxo-1H-pyridine-3-carbonitrile
1,2-dihydro-6-methyl-2-oxo-5-(imidazo(1,2-a)pyridin-6-yl)-3-pyridinecarbonitrile
1,2-dihydro-6-methyl-2-oxo-5-(imidazo[1,2-a]pyridin-6-yl)-3-pyridinecarbonitrile
5-{imidazo[1,2-a]pyridin-6-yl}-6-methyl-2-oxo-1,2-dihydropyridine-3-carbonitrile
SCHEMBL27661
CHEMBL1474900
DTXCID7028435
CHEBI:135019
JPAWFIIYTJQOKW-UHFFFAOYSA-N
BCP09781
HY-14254A
s5539
AKOS022179657
CCG-266964
CS-1190
SDCCGSBI-0633821.P001
NCGC00162385-01
NCGC00162385-02
NCGC00162385-03
NCGC00162385-05
NCGC00162385-10
AC-35198
AS-73630
DB-040705
4606A
NS00126108
C71263
D08294
Q7088538
BRD-K20745393-001-01-4
BRD-K20745393-003-01-0
1,2-dihydro-5-(imidazo[1,2-a]-pyridin-6-yl)-6-methyl-2-oxo-3-pyridinecarbonitrile
1,2-dihydro-5-(imidazo[1,2-a]pyridin-6-yl)-6-methyl-2-oxo-3-pyridinecarbonitrile
1,2-Dihydro-5-imidazo(1,2-alpha)pyridin-6-yl-6-methyl-2-oxonicotinonitrile.
1,2-dihydro-6-methyl-2-oxo-5-(imidazo[1,2-a]pyridin-6-yl)-3-pyridine carbonitrile
1,2-dihydro-6-methyl-5-(imidazo[1,2-a]pyridin-6-yl)-2-oxo-3-pyridinecarbonitrile