Phosphatidylcholine | Solubility of Things

Identification

Molecular formula

C₂₆H₅₄NO₈P

CAS number

28319-77-9

IUPAC name

[5-(hexadecanoylamino)-4-methoxy-2-phosphonooxy-pentyl]-trimethyl-ammonium

State

At room temperature, phosphatidylcholine is typically solid when pure and waxy in texture. However, as part of lecithin mixtures, it may be found in a viscous liquid state.

Melting point (Celsius)

252.00

Melting point (Kelvin)

525.15

Boiling point (Celsius)

460.00

Boiling point (Kelvin)

733.15

General information

Molecular weight

496.65g/mol

Molar mass

496.6510g/mol

Density

1.0300g/cm³

Appearence

Phosphatidylcholine generally appears as a whitish or slightly yellow powder or waxy solid. In some cases, it can also be found in a liquid form as a component of lecithin. It is often characterized by its waxy texture when solid.

Comment on solubility

Solubility of [5-(hexadecanoylamino)-4-methoxy-2-phosphonooxy-pentyl]-trimethyl-ammonium

The solubility of the compound [5-(hexadecanoylamino)-4-methoxy-2-phosphonooxy-pentyl]-trimethyl-ammonium, with the molecular formula C₂₆H₅₄NO₈P, can be quite intriguing, particularly due to its unique structural features. Here are some key points about its solubility characteristics:

Polarity: This compound exhibits a dual nature owing to its long hydrophobic hexadecanoyl chain and polar phosphono and ammonium groups. The interplay between hydrophobic and hydrophilic properties can lead to variable solubility in different solvents.
Aqueous Solubility: Generally, compounds with quaternary ammonium groups, such as the trimethyl-ammonium component, tend to have good solubility in water. However, the presence of the long hydrocarbon chain may restrict this solubility, resulting in a complex behavior.
Solvent Effects: The solubility in organic solvents can be expected to be higher due to the hydrophobic characteristics of the alkyl chain. For instance, solvents like chloroform or methanol may solubilize the compound effectively.
Temperature Influence: Temperature can also play a significant role in enhancing the solubility of this compound, as increased thermal energy often improves the solubilization process.
Applications: Understanding solubility is crucial for practical applications, particularly in drug formulation, where this compound may serve roles in delivery systems.

To sum up, the solubility of C₂₆H₅₄NO₈P is influenced by its unique structure, solvent interactions, and environmental conditions. It presents a fascinating case for study in terms of its physicochemical behavior and potential applications.

Interesting facts

Interesting Facts about [5-(hexadecanoylamino)-4-methoxy-2-phosphonooxy-pentyl]-trimethyl-ammonium

This fascinating compound, known for its unique structure and functional groups, plays a significant role in various biochemical applications. Here are some key points to consider:

Biological Importance: The presence of the phosphonooxy group suggests potential involvement in cellular signaling processes, making this compound of interest in biochemical research.
Fatty Acid Derivative: The hexadecanoyl portion indicates that this compound is likely derived from palmitic acid, which is prevalent in biological systems and essential for membrane structure and stability.
Surfactant Properties: Given its trimethyl-ammonium group, this compound exhibits surfactant properties, which could influence its behavior in aqueous solutions, particularly in the formation of micelles and vesicles.
Potential Therapeutic Uses: Compounds with similar structural features are often explored for drug delivery systems due to their ability to encapsulate therapeutic agents and facilitate cellular uptake.

As a chemistry student looking to understand this compound's potential applications, one might reflect on the words of renowned chemist Linus Pauling: "The best way to have a good idea is to have a lot of ideas." This highlights the importance of innovative thinking in exploring compounds like this one.

Overall, [5-(hexadecanoylamino)-4-methoxy-2-phosphonooxy-pentyl]-trimethyl-ammonium represents the intersection of organic chemistry and biochemistry, opening avenues for future research and development in the field of drug design and nanotechnology.

Synonyms

3,5-Dioxa-9-aza-4-phosphapentacosan-1-aminium,4-hydroxy-7-methoxy-N,N,N-trimethyl-10-oxo-, inner salt, 4-oxide (9CI)