Interesting facts
Exploring 5-Fluoro-1-tetrahydrofuran-2-yl-pyrimidine-2,4-dione
5-Fluoro-1-tetrahydrofuran-2-yl-pyrimidine-2,4-dione is a fascinating chemical compound with a variety of intriguing characteristics and applications. Its unique structure allows for interesting interactions within biochemical and organic systems. Here are some key points that illustrate its significance:
- Pharmaceutical Potential: This compound features a pyrimidine core, which is commonly found in numerous biologically active molecules. Pyrimidines are known for their roles in nucleic acids and are often essential in the design of novel drugs.
- Fluorine Substitution: The presence of fluorine not only impacts the compound's stability and reactivity but also enhances its lipophilicity, making it more suitable for penetrating biological membranes.
- Synthetic Applications: The tetrahydrofuran moiety is significant in organic chemistry as a solvent and as an intermediate in various synthetic pathways. This compound could be used in the synthesis of complex organic molecules.
- Research Interest: Given its structure, researchers are exploring the compound's potential in anti-cancer therapies and its effects on cellular pathways, promising avenues for further studies.
As with many advanced compounds, understanding the properties and reactivity of 5-fluoro-1-tetrahydrofuran-2-yl-pyrimidine-2,4-dione is crucial for its application in drug development and organic synthesis. Its intriguing combination of various functional groups and the presence of fluorine make it a subject of continuous study in the field of medicinal and organic chemistry.
Synonyms
tegafur
17902-23-7
Ftorafur
Futraful
Sinoflurol
Fental
Fluorofur
Citofur
Neberk
Coparogin
Furafluor
Furofutran
Nitobanil
Exonal
Fulfeel
Lifril
Lamar
Tefsiel C
Florafur
Franroze
Furflucil
Sunfral
Riol
5-Fluoro-1-(tetrahydro-2-furyl)uracil
FT-207
5-fluoro-1-(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
Franrose
Phthorafur
Sunfural
Fulaid
1-(2-Tetrahydrofuryl)-5-fluorouracil
Racemic Ftorafur
Phthorafur [Czech]
MJF-12264
Atillon
Tegafurum
5-fluoro-1-(oxolan-2-yl)pyrimidine-2,4-dione
Tegafurum [INN-Latin]
2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-
5-FLUORO-1-(TETRAHYDRO-2-FURFURYL)URACIL
NSC-148958
URACIL, 5-FLUORO-1-(TETRAHYDRO-2-FURYL)-
CCRIS 2762
5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-pyrimidinedione
N1-(2-tetrahydrofuryl)-5-fluorouracil
1-(Tetrahydrofuran-2-yl)-5-fluorouracil
5-Fluoro-1-(tetrahydrofuran-2-yl)uracil
FT207
EINECS 241-846-2
FT 207
MFCD00012351
Uracil, 1-(tetrahydrofuran-2-yl)-5-fluoro-
Atillon (TN)
BRN 0525766
N1-(2'-Tetrahydrofuryl)-5-fluorouracil
Tegafur [USAN:INN:BAN:JAN]
1548R74NSZ
FT-207 (NSC 148958)
1-(Tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione
N(sub 1)-(2-Tetrahydrofuryl)-5-fluorouracil
TEGAFUR [INN]
TEGAFUR [JAN]
TEGAFUR [USAN]
TEGAFUR [MI]
TEGAFUR [MART.]
TEGAFUR [WHO-DD]
N(sub 1)-(2'-Furanidyl)-5-fluouracil [Czech]
TEGAFUR [EMA EPAR]
5-Fluoro-1-(tetrahydro-3-furyl)uracil
N(sub 1)-(2'-Furanidyl)-5-fluouracil
5-fluoro-1-tetrahydrofuran-2-yl-pyrimidine-2,4-dione
MLS000069497
TEYSUNO COMPONENT TEGAFUR
CHEBI:32188
2,4(1H,3H)Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-
DTXSID001009966
5-24-06-00285 (Beilstein Handbook Reference)
N1-(2'-Furanidyl)-5-fluorouracil
5-fluoro-1-(tetrahydro-2-furyl)-uracil
SMR000059106
Tegafurum (INN-Latin)
5-Fluoro-1-(tetrahydro-2-furanyl)-2,4(1H,3H)-pyrimidinedione
5-fluoro-1-(oxolan-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
TEGAFUR (MART.)
82294-77-7
C8H9FN2O3
Fluorafur
Utefos
NSC148958
NSC 148958
5-Fluoro-1-((2RS)-tetrahydrofuran-2-yl)uracil
5-Fluoro-1-[(2RS)-tetrahydrofuran-2-yl]uracil
Ftoralon
Tefsiel
Ftoral
1-(Tetrahydro-2-furanyl)-5-fluorouracil
UNII-1548R74NSZ
Ftorafur;Tegafur
Tegafur?
1-(2-TETRAHYDROFORMYL)-5-FLUOROURACIL
NCGC00159418-02
NCGC00159418-05
Tegafur (Standard)
Tegafur ,(S)
S-1 component tegafur
TS-1 (Salt/Mix)
TS-1 component tegafur
Opera_ID_1726
UPCMLD-DP063
SCHEMBL4552
MLS000759414
MLS001076521
MLS001424119
CHEMBL20883
Tegafur (JP18/USAN/INN)
DTXCID701305
F-5-FU
2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-[(2R)-tetrahydro-2-furanyl]-
UPCMLD-DP063:001
GTPL10513
L01BC03
HMS1665I05
HMS2051B15
HMS2090K04
HMS2232E05
HMS3371H21
HMS3393B15
HMS3654P13
HMS3715D14
N1-(2'-Furanidyl)-5-fluouracil
BCP22714
TEGAFUR COMPONENT OF TEYSUNO
5-fluoro-1-(tetrahydrofuran-2-yl)
BBL027795
CCG-50110
HY-17400R
STK528044
Tegafur, >=98% (HPLC), powder
5-Fluoro-1-(2-tetrahydrofuryl)uracil
AKOS000121279
AC-2112
CCG-100959
CS-1128
DB09256
FF08013
NC00209
1-(tetrahydro-2-furyl)-5-fluorouracil
2,4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-, didehydroderiv.
5-fluoro-1-(2-tetrahydrofuranyl)uracil
N1 -(2-tetrahydrofuryl)-5-fluorouracil
NCGC00159418-04
AS-13528
BP-58663
HY-17400
Tegafur (FT-207; NSC 148958)
WR-220066
NS00007105
EN300-21668
D01244
AB00572620-15
Q413370
SR-01000639511
SR-01000639511-1
SR-01000639511-4
Z104508106
5-fluoro-1-tetrahydro-furan-2-yl-1H-pyrimidine-2,4-dione
pyrimidine-2,4(1H,3H)-dione, 5-fluoro-1-(2-oxolanyl)-
5-Fluoro-1-tetrahydro-2-furanyl-2,4(1H,3H)-pyrimidinedione
5-Fluoro-1-(tetrahydro-2-furanyl)-2,4-(1H,3H)-pyrimidinedione
2, 4(1H,3H)-Pyrimidinedione, 5-fluoro-1-(tetrahydro-2-furanyl)-, (R)-
Solubility of 5-fluoro-1-tetrahydrofuran-2-yl-pyrimidine-2,4-dione
The solubility of 5-fluoro-1-tetrahydrofuran-2-yl-pyrimidine-2,4-dione (C4H4FN3O) is a key factor in understanding its potential applications and behavior in various environments. This compound, like many others, exhibits unique characteristics:
When evaluating solubility, it’s essential to consider factors such as temperature and pH, which can significantly influence a compound's solubility. As noted, “the solubility of a compound is often a competing balance of interactions between solute and solvent.” This balance can determine how effectively 5-fluoro-1-tetrahydrofuran-2-yl-pyrimidine-2,4-dione can dissolve in various media, which is crucial for its utility in chemical processes and applications.