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(5-ethylquinuclidin-2-yl)-(6-methoxy-4-quinolyl)methanol

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Identification
Molecular formula
C21H28N2O2
CAS number
NA
IUPAC name
(5-ethylquinuclidin-2-yl)-(6-methoxy-4-quinolyl)methanol
State
State

This compound is in a solid state at room temperature, typically existing as a crystalline powder.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
520.00
Boiling point (Kelvin)
793.15
General information
Molecular weight
356.47g/mol
Molar mass
356.4660g/mol
Density
1.3400g/cm3
Appearence

The compound is typically a crystalline solid that can appear as a white or off-white powder. As with many chemical compounds, specific appearance characteristics such as crystal form can vary depending on the method of preparation and degree of purification.

Comment on solubility

Solubility of (5-ethylquinuclidin-2-yl)-(6-methoxy-4-quinolyl)methanol

The solubility of this compound, C21H28N2O2, can be influenced by several factors, including its molecular structure, functional groups, and the presence of polar or non-polar regions.

Factors Affecting Solubility:

  • Polarity: The presence of hydroxyl (-OH) and methoxy (-OCH3) groups suggests that the compound may exhibit some degree of polarity, potentially enhancing its solubility in polar solvents such as water.
  • Molecular Size: The relatively large size and complex structure of the molecule may limit its solubility in highly polar solvents.
  • Hydrogen Bonding: The ability of hydroxyl groups to participate in hydrogen bonding is critical, potentially increasing solubility in aqueous solutions.

In general, compounds similar to (5-ethylquinuclidin-2-yl)-(6-methoxy-4-quinolyl)methanol are observed to be:

  1. More soluble in organic solvents like ethanol and methanol.
  2. Moderately soluble in water, depending on the specific conditions and concentration.

Knowing the solubility profile is crucial for applications in pharmaceuticals and chemical synthesis, as it can directly influence the bioavailability and reactivity of the compound.

Interesting facts

Interesting Facts about (5-ethylquinuclidin-2-yl)-(6-methoxy-4-quinolyl)methanol

(5-ethylquinuclidin-2-yl)-(6-methoxy-4-quinolyl)methanol is a fascinating compound that features a unique combination of structural elements, combining both a quinuclidine and a quinoline moiety. This structural diversity opens up a variety of applications, particularly in medicinal chemistry.

Key Highlights:

  • Pharmacological Potential: Given the presence of the quinuclidine ring, this compound could exhibit interesting pharmacological properties, such as acting as a potential therapeutic agent in areas like neurology and psychiatry.
  • Quinoline Derivative: The incorporation of the quinoline structure suggests potential anti-inflammatory and antimicrobial characteristics, as quinolines have been widely studied for these properties.
  • Synthetic Avenues: The synthesis of this compound involves intricate multistep processes, allowing chemists to explore various synthetic pathways to optimize yield and purity.
  • Versatility: This compound can serve as a scaffold for further chemical modifications, providing opportunities to create a library of related compounds with potentially enhanced biological activity.

Research Implications:

Studies regarding (5-ethylquinuclidin-2-yl)-(6-methoxy-4-quinolyl)methanol highlight the importance of interdisciplinary approaches in chemistry. As one researcher noted, "The integration of medicinal and synthetic chemistry can lead to transformative discoveries."
Such compounds provide valuable insights into the development of new drugs and biological probes, showcasing the power of structural modifications in biological applications.

This compound not only represents an intersection of different chemical disciplines but also invites curiosity about its potential uses. The ongoing research surrounding it emphasizes the importance of exploring diverse chemical entities to unlock new therapeutic potentials.

Synonyms
hydroquinidine
HYDROQUININE
Dihydroquinidine
Dihydroquinine
Dihydrochinidin
1076202-13-5
10,11-Dihydroquinidine
{5-ethyl-1-azabicyclo[2.2.2]octan-2-yl}(6-methoxyquinolin-4-yl)methanol
MFCD00151107
Cinchonan-9-ol, 10,11-dihydro-6'-methoxy-, (9S)-
NSC-41799
[5-Ethyl-1-azabicyclo[2.2.2]octan-2-yl](6-methoxyquinolin-4-yl)methanol
(S)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol
6'-Methoxy-10,11-dihydrocinchonan-9-ol #
Quinine,11-dihydro-
Dihydroquinidine;(+)-Hydroquinidine;Hydroconquinine
SCHEMBL308963
DTXSID00903284
LJOQGZACKSYWCH-UHFFFAOYSA-N
BCP18337
NSC41799
AKOS015895298
AC-1818
(1S)((4S,2R,5R)-5-ethylquinuclidin-2-yl)(6-methoxy(4-quinolyl))methan-1-ol
NCGC00094828-01
NCGC00094828-02
LS-14801
SY009729
SY009748
EN300-270186
Cinchonan-9-ol,11-dihydro-6'-methoxy-, (8.alpha.,9R)-
(8a, 9R)-10, 11-dihydro-6'-methoxycinchonan-9-ol, dihydroquinine