Skip to main content

Pentobarbital

ADVERTISEMENT
Identification
Molecular formula
C11H18N2O3
CAS number
76-74-4
IUPAC name
5-ethyl-5-isopropyl-hexahydropyrimidine-2,4,6-trione
State
State

At room temperature, pentobarbital is typically in a solid state, characterized by its crystalline form. It remains stable under normal conditions but should be kept in a dry and cool place to maintain its integrity.

Melting point (Celsius)
127.00
Melting point (Kelvin)
400.15
Boiling point (Celsius)
232.00
Boiling point (Kelvin)
505.15
General information
Molecular weight
226.29g/mol
Molar mass
226.2850g/mol
Density
1.2300g/cm3
Appearence

Pentobarbital appears as a white crystalline powder. It is typically odorless, although some variations might have a very faint odor. The crystals can take on various forms, but they are most commonly seen as a fine powder.

Comment on solubility

Solubility of 5-ethyl-5-isopropyl-hexahydropyrimidine-2,4,6-trione

The solubility of 5-ethyl-5-isopropyl-hexahydropyrimidine-2,4,6-trione is an intriguing topic due to a variety of factors that govern its behavior in different solvents. Understanding its solubility can aid in predicting its applications and reactivity:

  • Solvent Polarity: The compound's solubility is highly dependent on the polarity of the solvent. Polar solvents (like water) may lead to different solubility characteristics compared to non-polar solvents (like hexane).
  • Hydrogen Bonding: The presence of functional groups that can engage in hydrogen bonding can greatly affect solubility. For this compound, analyzing its potential hydrogen bonding sites is crucial.
  • Temperature: As with many chemical compounds, an increase in temperature often leads to increased solubility. This can be particularly significant for organic compounds that are less soluble at room temperature.
  • Concentration: The concentration of the compound in solution may also inform its solubility limits, as solvent saturation can occur.

Moreover, in general terms, many complex organic compounds such as 5-ethyl-5-isopropyl-hexahydropyrimidine-2,4,6-trione often exhibit limited aqueous solubility due to their hydrophobic hydrocarbon chains. However, when assessing solubility, it can be advantageous to consider the following:

  • **Test various solvent systems** to determine the optimal conditions for dissolution.
  • **Utilize techniques like sonication** or stirring to enhance solubility for laboratory applications.
  • Soluble salts or derivatization might also improve overall solubility in applicable scenarios.

In conclusion, while specific data on 5-ethyl-5-isopropyl-hexahydropyrimidine-2,4,6-trione's solubility may be limited, understanding the underlying principles can lead to informed and effective use of this compound in various chemical contexts.

Interesting facts

Interesting Facts About 5-Ethyl-5-Isopropyl-Hexahydropyrimidine-2,4,6-Trione

5-Ethyl-5-isopropyl-hexahydropyrimidine-2,4,6-trione, a fascinating chemical compound, holds a unique position in organic chemistry due to its complex structure and diverse applications. Here are some intriguing insights into this compound:

  • Structural Variety: This compound exhibits a remarkable structure characterized by a hexahydropyrimidine ring, showcasing the beauty of heterocyclic chemistry. The presence of multiple substituents, such as ethyl and isopropyl groups, contributes to its unique properties.
  • Reactivity: The trione functional groups present in the structure can participate in various chemical reactions, making this compound an interesting subject for synthetic chemistry. It is known to react well with nucleophiles and has the potential to serve as a precursor for more complex molecules.
  • Biological Relevance: Compounds with similar structures often exhibit significant biological activity. Research has highlighted that derivatives of pyrimidine are widely studied for their potential as pharmaceuticals. While specific studies on this compound might be scarce, it could inspire further explorations in medicinal chemistry.
  • Applications: Due to its potential reactivity, it could find applications in agrochemicals, as intermediates in drug synthesis, or in materials science as a component of polymeric materials.
  • Analytical Chemistry: Understanding and characterizing such compounds requires advanced analytical techniques. Spectroscopic methods such as NMR and IR spectroscopy play crucial roles in identifying the distinct functional groups and confirming structure.

"In the realm of organic compounds, the more complex the structure, the greater the potential for discovery."

This compound exemplifies a rich area of study where chemistry intersects with various applications, making it a compelling topic for both scientific research and educational pursuits.

Synonyms
PROBARBITAL
Probarbitone
Ipral
Vasalgin
Irenal
5-Ethyl-5-isopropylbarbituric acid
Ethylisopropylbarbituric acid
76-76-6
Isopropyl ethyl barbituric acid
Barbituric acid, 5-ethyl-5-isopropyl-
NSC 120742
5-ethyl-5-propan-2-yl-1,3-diazinane-2,4,6-trione
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylethyl)-
R87TF75S6O
5-Ethyl-5-(1-methylethyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
NSC-120742
BRN 0167241
UNII-R87TF75S6O
5-24-09-00159 (Beilstein Handbook Reference)
SCHEMBL715090
5-ethyl-5-isopropylpyrimidine-2,4,6(1h,3h,5h)-trione
CHEMBL2110696
DTXSID30226897
HHLXJTDUHFBYAU-UHFFFAOYSA-N
NSC120742
AKOS006273375
WLN: T6VMVMV FHJ FY1&1 F2
5-ETHYL-5-ISOPROPYL-BARBITURIC ACID
NS00114089
Q7246894
5-Ethyl-5-isopropyl-2,4,6(1H,3H,5H)-pyrimidinetrione #
2,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(1-methylethyl)-
5-ETHYL-5-ISOPROPYLHEXAHYDROPYRIMIDINE-2,4,6-TRIONE
pyrimidine-2,4,6(1H,3H,5H)-trione, 5-ethyl-5-isopropyl-