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Pentobarbital

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Identification
Molecular formula
C11H18N2O3
CAS number
76-74-4
IUPAC name
5-ethyl-5-isopentyl-hexahydropyrimidine-2,4,6-trione
State
State

At room temperature, Pentobarbital is in a solid state. It is stable and tends to remain as a solid powder under standard conditions.

Melting point (Celsius)
175.00
Melting point (Kelvin)
448.15
Boiling point (Celsius)
420.00
Boiling point (Kelvin)
693.15
General information
Molecular weight
226.28g/mol
Molar mass
226.2780g/mol
Density
1.0552g/cm3
Appearence

Pentobarbital is a crystalline solid, appearing typically as a white or almost white powder. It is often used in its sodium salt form, which is also a white crystalline powder. The compound is known for its bitter taste.

Comment on solubility

Solubility of 5-ethyl-5-isopentyl-hexahydropyrimidine-2,4,6-trione

The solubility of 5-ethyl-5-isopentyl-hexahydropyrimidine-2,4,6-trione (C11H18N2O3) is a subject of interest due to its unique structural attributes. This compound, characterized by a complex polycyclic framework, presents distinctive solubility properties influenced by several factors:

  • Polarity: The presence of carbonyl (C=O) functional groups typically enhances solubility in polar solvents such as water.
  • Hydrophobic Chains: Its ethyl and isopentyl groups contribute to hydrophobic character, suggesting reduced solubility in water but potentially good solubility in organic solvents.
  • Temperature Effects: Higher temperatures may promote solubility, facilitating interactions between molecules and the solvent.

In summary, while precise solubility data is not extensively documented, it can be inferred that this compound is likely to be more soluble in organic solvents than in polar solvents, owing to the balance of its hydrophilic and hydrophobic components. As always, experimental data is essential for confirming these theoretical insights.

Interesting facts

Interesting Facts about 5-ethyl-5-isopentyl-hexahydropyrimidine-2,4,6-trione

5-ethyl-5-isopentyl-hexahydropyrimidine-2,4,6-trione is a fascinating compound, known for its unique chemical structure and diverse applications within the field of medicinal chemistry. Here are some intriguing aspects of this compound:

  • Structural Complexity: The compound features a hexahydropyrimidine core, which is a distinctive framework that contributes to its pharmacological properties. The presence of multiple functional groups, including trione, enhances its ability to interact with biological systems.
  • Potential Therapeutic Uses: Due to its unique properties, compounds of this type are often investigated for potential applications in drug development, particularly in the treatment of various diseases. Research indicates that similar structures may exhibit anti-inflammatory or anticancer activities.
  • Mechanism of Action: The specific arrangement of atoms in 5-ethyl-5-isopentyl-hexahydropyrimidine-2,4,6-trione may allow it to act on particular biological targets, influencing pathways that regulate cell growth and response to stimuli.
  • Synthetic Approaches: The synthesis of this compound may require advanced techniques in organic chemistry, illustrating the creativity and precision needed in modern chemical research to construct complex molecules.
  • Research Significance: As scientists continue to explore the capabilities of similar compounds, the insights gained from studying 5-ethyl-5-isopentyl-hexahydropyrimidine-2,4,6-trione can pave the way for new discoveries in therapeutic strategies.

In summary, 5-ethyl-5-isopentyl-hexahydropyrimidine-2,4,6-trione stands out as a remarkable compound, not just for its intricate structure, but for its potential implications in health and science. As we delve deeper into its properties, there is much to be learned about the intersection of chemistry and medicine.

Synonyms
amobarbital
Amylobarbitone
Isomytal
Amylobarbital
Barbamil
Barbamyl
Amytal
57-43-2
Amobarbitone
Amylbarbitone
Pentymal
Talamo
Barbamyl acid
Binoctal
Dorlotyn
Dormytal
Eunoctal
Mylodorm
Pentymalum
Schiwanox
Sednotic
Stadadorm
Amasust
Amital
Amospan
Amybal
Robarb
Somnal
Sumital
Isomyl
AMAL
Isoamylethylbarbituric acid
5-Ethyl-5-isopentylbarbituric acid
Ethylisopentylbarbituric acid
5-Ethyl-5-isoamylbarbituric acid
Amobarbitale
Amobarbitalum
5-Ethyl-5-isoamylmalonyl urea
5-Ethyl-5-(3-methylbutyl)barbituric acid
5-Isoamyl-5-ethylbarbituric acid
Amobarbital cii
Barbituric acid, 5-ethyl-5-isopentyl-
NSC 10815
5-Ethyl-5-isopentylbarbitursaeure
Amobarbitalum [INN-Latin]
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(3-methylbutyl)-
5-Ethyl-5-(3-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione
CCRIS 5454
HSDB 3286
UNII-GWH6IJ239E
EINECS 200-330-7
GWH6IJ239E
NSC-10815
5-ethyl-5-(3-methylbutyl)-1,3-diazinane-2,4,6-trione
component of Dexamyl
component of Q-Caps
CHEBI:2673
DTXSID9020081
component of 15-90
5-ethyl-5-(3-methylbutyl)pyrimidine-2,4,6(1H,3H,5H)-trione
component of Amo-Dextrosule
DTXCID0081
Amobarbital [USP:INN:BAN:JAN]
NCGC00247711-01
Amobarbitale [DCIT]
Amobarbitalum (INN-Latin)
AMOBARBITAL (MART.)
AMOBARBITAL [MART.]
AMOBARBITAL (EP IMPURITY)
AMOBARBITAL [EP IMPURITY]
AMOBARBITAL CII (USP-RS)
AMOBARBITAL CII [USP-RS]
Amobarbital (USP:INN:BAN:JAN)
isopentobarbital
WLN: T6VMVMV FHJ F2 F2Y1&1
Isomytal (TN)
2,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(3-methylbutyl)-
5-Ethyl-5-(3-methylbutyl)-2,6(1H,3H,5H)-pyrimidinetrione
EUROCTAL
STATADORM
Dexamyl (Salt/Mix)
AMOBARBITAL [MI]
AMOBARBITAL [INN]
AMOBARBITAL [JAN]
AMOBARBITAL [HSDB]
Amobarbital (JP18/INN)
AMOBARBITAL [VANDF]
BIDD:PXR0091
Oprea1_587446
SCHEMBL43780
AMOBARBITAL [WHO-DD]
CBDivE_006514
DivK1c_000994
CHEMBL267894
ISOAMYETHYLBARBITURIC ACID
SCHEMBL15364946
component of Dexamyl (Salt/Mix)
KBio1_000994
VIROVYVQCGLCII-UHFFFAOYSA-
component of Q-Caps (Salt/Mix)
N05CA02
NINDS_000994
component of 15-90 (Salt/Mix)
Amobarbital 0.1 mg/ml in Methanol
Amobarbital 1.0 mg/ml in Methanol
NSC10815
NSC32406
Tox21_112866
NSC-32406
NSC120800
Barbituric acid, 5-ethyl-5-isoamyl-
Barbituric acid, 5-ethyl-5-isopentyl
DB01351
NSC-120800
CAS-57-43-2
component of Amo-Dextrosule (Salt/Mix)
IDI1_000994
NS00008808
C07536
D00555
Q415850
5-Ethyl-5-isopentyl-2,4,6(1H,3H,5H)-pyrimidinetrione #
pyrimidine-2,4,6(1H,3H,5H)-trione, 5-ethyl-5-isopentyl-
2,4,6(1H,3H,5H)-Pyrimidinetrione, 5-ethyl-5-(3-methylbutyl)-,
5-Ethyl-5-(3-methylbutyl)-2,4,6-(1H,3H,5H)-pyrimidinetrione
200-330-7
InChI=1/C11H18N2O3/c1-4-11(6-5-7(2)3)8(14)12-10(16)13-9(11)15/h7H,4-6H2,1-3H3,(H2,12,13,14,15,16)