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Paramethadione

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Identification
Molecular formula
C12H13NO2
CAS number
115-67-3
IUPAC name
5-ethyl-3-methyl-5-phenyl-imidazolidine-2,4-dione
State
State

At room temperature, Paramethadione is in a solid state in the form of its crystalline structure.

Melting point (Celsius)
58.00
Melting point (Kelvin)
331.15
Boiling point (Celsius)
546.00
Boiling point (Kelvin)
819.15
General information
Molecular weight
222.24g/mol
Molar mass
222.2630g/mol
Density
1.3000g/cm3
Appearence

Paramethadione typically appears as a white crystalline solid. It is an odorless compound.

Comment on solubility

Solubility of 5-ethyl-3-methyl-5-phenyl-imidazolidine-2,4-dione

The solubility of 5-ethyl-3-methyl-5-phenyl-imidazolidine-2,4-dione (C12H13NO2) is influenced by its molecular structure, which includes both hydrophobic and hydrophilic characteristics. Understanding its solubility behavior is crucial for practical applications. Here are some key points regarding its solubility:

  • Solvent Properties: This compound is likely to exhibit better solubility in organic solvents such as ethyl acetate, acetone, and dimethyl sulfoxide (DMSO) rather than in polar solvents like water.
  • Functional Groups: The presence of the imidazolidine structure introduces potentially polar interactions, although the bulky ethyl and phenyl substituents may inhibit full solubility in highly polar mediums.
  • Temperature Influence: Solubility can also increase with temperature. Hence, heating organic solvents may enhance the dissolution of this compound.
  • pH Dependence: The solubility might be affected by the pH of the solution, especially if the compound can ionize, which alters its solubility profile in aqueous solutions.

In summary, while 5-ethyl-3-methyl-5-phenyl-imidazolidine-2,4-dione may display limited solubility in water, it is expected to be more soluble in non-polar or weakly polar organic solvents. This behavior aligns with many compounds that possess a significant degree of hydrophobic character due to their molecular structure.

Interesting facts

Exploring 5-ethyl-3-methyl-5-phenyl-imidazolidine-2,4-dione

5-ethyl-3-methyl-5-phenyl-imidazolidine-2,4-dione, a fascinating compound with a unique structure, is part of the imidazolidine family, which is characterized by its five-membered ring containing nitrogen atoms. Here are some intriguing aspects of this compound:

  • Diverse Applications: This compound shows promise in pharmaceutical chemistry, particularly in the development of medications that target various diseases due to its unique molecular structure.
  • Synthetic Intermediates: It is often utilized as a key intermediate in synthesizing other organic compounds, making it crucial in laboratory settings.
  • Stability: The imidazolidine ring provides a certain level of stability, which can be beneficial in various chemical reactions.
  • Mechanistic Studies: The interactions and reactions involving this compound can reveal valuable insights into the behavior of similar nitrogen-containing heterocycles.
  • Research Potential: Continuous research may uncover new properties, enhancing its potential uses in different fields beyond traditional chemistry.

As chemists delve deeper into the study of 5-ethyl-3-methyl-5-phenyl-imidazolidine-2,4-dione, they might discover groundbreaking applications or uncover novel derivatives that could revolutionize synthetic methodologies. Its blending of ethyl, methyl, and phenyl groups with the imidazolidine core is a testament to the creativity within organic synthesis.

Understanding such compounds not only expands our knowledge of organic chemistry but also enhances our ability to innovate in drug design and development. The quest for knowledge in this area reiterates the wisdom of famed chemist Linus Pauling who said, "The best way to have a good idea is to have a lot of ideas."

Synonyms
MEPHENYTOIN
Methoin
50-12-4
Mesantoin
Methylphenetoin
Phenantoin
Epiazin
Methyl hydantoin
Insulton
Sedantoin
Sedantoinal
Triantoin
Metydan
Sacerno
Fenantoin
5-ethyl-3-methyl-5-phenylimidazolidine-2,4-dione
Epilan
Phenylethylmethylhydantoin
Mephenytoinum
Mefenitoina
Mephenytoine
Mesontoin
3-Ethylnirvanol
(+/-)-Mephenytoin
mephentoin
Mephenetoinum
2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-
5-Ethyl-3-methyl-5-phenylhydantoin
3-Methyl-5,5-phenylethylhydantoin
3-Methyl-5-ethyl-5-phenylhydantoin
NSC-34652
5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione
Hydantoin, 5-ethyl-3-methyl-5-phenyl-
5-Ethyl-3-methyl-5-phenylimidazolidin-2,4-dione
Mefenitoina [INN-Spanish]
Mephenytoine [INN-French]
Mephenytoinum [INN-Latin]
5-Ethyl-5-fenyl-3-methylhydantoin
5-Ethyl-3-methyl-5-phenyl-2,4(3H,5H)-imidazoledione
rac-Mephenytoin
HSDB 3581
EINECS 200-012-8
NSC 34652
UNII-R420KW629U
l-Mephenytoin
BRN 0017282
R420KW629U
3-Methyl-5,5-ethylphenylhydantoin
NSC34652
ETHYLMETHYLHYDANTOIN
50-12-4 (racemic)
CHEBI:6757
Mefenetoin
Mesdontoin
DTXSID9023257
Methyl Phenetoin
Mephenytoin [USAN:USP:INN:BAN]
Sedantional
Gerot-epilan
(+/-)-5-Ethyl-3-methyl-5-phenylhydantoin
Mefenitoina (INN-Spanish)
Mephenytoine (INN-French)
Mephenytoinum (INN-Latin)
Phenetoin, Methyl
MEPHENYTOIN (MART.)
MEPHENYTOIN [MART.]
MEPHENYTOIN (USP IMPURITY)
MEPHENYTOIN [USP IMPURITY]
Mephenytoin (USAN:USP:INN:BAN)
DL-Mephenytoin
Mesantoin (TN)
(-)-5-Ethyl-3-methyl-5-phenylhydantoin
5-Ethyl-5-fenyl-3-methylhydantoin [Czech]
SR-05000001478
Mephenytoin (USP/INN)
5 Ethyl 3 Methyl 5 Phenylhydantoin
(+-)-5-Ethyl-3-methyl-5-phenylhydantoin
()-Mephenytoin
3-Methyl-5, 5-ethylphenylhydantoin
l-3-Methyl-5-ethyl-5-phenylhydantoin
Mephenytoin (Standard)
Spectrum_001494
MEPHENYTOIN [MI]
Prestwick0_001108
Prestwick1_001108
Prestwick2_001108
Prestwick3_001108
Spectrum4_001094
MEPHENYTOIN [INN]
MEPHENYTOIN [HSDB]
MEPHENYTOIN [USAN]
CHEMBL861
MEPHENYTOIN [VANDF]
Oprea1_289074
SCHEMBL21766
BSPBio_001216
KBioGR_001508
KBioSS_001974
MEPHENYTOIN [WHO-DD]
MLS002154157
DivK1c_000937
SPBio_003088
BPBio1_001338
DTXCID003257
GTPL7223
NIOSH/MU2276000
HMS502O19
HY-B1184R
KBio1_000937
KBio2_001974
KBio2_004542
KBio2_007110
(+/-)-5-Ethyl-3-methyl-5-phenyl-2,4-imidazolidinedione
MEPHENYTOIN [ORANGE BOOK]
N03AB04
NINDS_000937
2,4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-, (+-)-
GLXC-27003
HMS1571M18
HMS2089J22
HMS2098M18
HMS2230E21
HMS3369F15
HMS3715M18
2, 5-ethyl-3-methyl-5-phenyl-
AAA05012
HY-B1184
Mephenytoin 1.0 mg/ml in Methanol
BDBM50103593
MFCD00022407
WLN: T5MVNV EHJ C1 E2 ER
AKOS015962176
CCG-213191
CS-4793
DB00532
IDI1_000937
NCGC00165924-01
NCGC00165924-02
AC-15964
AS-56694
DA-55346
SMR001233457
SY068296
DB-055496
AB00052368
MU22760000
NS00008986
(.+/-.)-5-Ethyl-3-methyl-5-phenylhydantoin
3-METHYL-5,5-PHENYLETHYLMETHYLHYDANTOIN
BIM-0051837.0001
D00375
EN300-697588
AB00052368-07
AB00052368_08
Hydantoin, 5-ethyl-3-methyl-5-phenyl-, (-)-
5-Ethyl-3-methyl-5-phenyl-2,5H)-imidazoledione
5-ethyl-3-methyl-5-phenyl-imidazolidine-2,4-dione
Q1175385
SR-05000001478-1
SR-05000001478-3
2, 4-Imidazolidinedione, 5-ethyl-3-methyl-5-phenyl-
BRD-A83937277-001-03-0
BRD-A83937277-001-10-5
Z53843610
4-ethyl-2-hydroxy-1-methyl-4-phenyl-4,5-dihydro-1H-imidazol-5-one
2,4-IMIDAZOLIDINEDIONE, 5-ETHYL-3-METHYL-5-PHENYL-, (+/-)-
200-012-8