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5-Ethyl-2-methylpiperidine

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Identification
Molecular formula
C8H17N
CAS number
622-32-0
IUPAC name
5-ethyl-2-methyl-piperidine
State
State

At room temperature, 5-Ethyl-2-methylpiperidine is in a liquid state. Its boiling point is relatively low for an organic compound, signifying that it transitions to the gaseous state at temperatures above typical ambient conditions. It remains stable and liquid under normal atmospheric pressure.

Melting point (Celsius)
-62.00
Melting point (Kelvin)
211.15
Boiling point (Celsius)
148.70
Boiling point (Kelvin)
421.85
General information
Molecular weight
113.21g/mol
Molar mass
113.2070g/mol
Density
0.8165g/cm3
Appearence

5-Ethyl-2-methylpiperidine is a colorless to pale yellow liquid. It may appear slightly oily in texture and have a distinct amine-like odor, which is characteristic of many piperidine derivatives. The liquid may also faintly reflect light, giving it a slightly shiny appearance depending on the purity and surface it is on.

Comment on solubility

Solubility of 5-ethyl-2-methyl-piperidine

5-ethyl-2-methyl-piperidine, with its unique alkyl substituents, presents intriguing properties when it comes to solubility. Generally, the solubility of piperidine derivatives can be influenced by several factors:

  • Polarity: The presence of the piperidine ring often increases polarity which can enhance solubility in polar solvents.
  • Hydrogen Bonding: The amine group may engage in hydrogen bonding with solvent molecules, further increasing its solubility in polar solvents like water.
  • Alkyl Chains: The ethyl and methyl groups can make the molecule less polar than smaller piperidine derivatives, which may reduce its solubility in highly polar solvents.
  • Temperature: Increased temperature may affect solubility positively, allowing greater dissolving capabilities in various solvents.

As a result, 5-ethyl-2-methyl-piperidine is expected to be moderately soluble in water and more soluble in organic solvents, with solubility tendencies varying significantly based on the solvent used.

In conclusion, while the exact solubility can vary based on conditions, understanding these key aspects gives insightful predictions regarding how this compound interacts with different solvents.

Interesting facts

Exploring 5-Ethyl-2-methyl-piperidine

5-Ethyl-2-methyl-piperidine is an intriguing nitrogen-containing heterocyclic compound that has garnered attention in the fields of organic chemistry and medicinal chemistry. This compound features a piperidine ring, which is a saturated six-membered ring containing one nitrogen atom. Here are some captivating aspects of 5-ethyl-2-methyl-piperidine:

  • Piperidine Structure: The piperidine framework is known for its versatility as a building block in synthetic organic chemistry. Due to its stability and moderate reactivity, it serves as a precursor for a wide variety of functionalized compounds.
  • Pharmaceutical Potential: Compounds derived from piperidine, including 5-ethyl-2-methyl-piperidine, are often investigated for their potential therapeutic properties. Notably, piperidine derivatives have shown promise in the development of drugs targeting neurological disorders, pain management, and even cancer treatments.
  • Substituent Influence: The specific ethyl and methyl substitutions on the piperidine ring can significantly alter the compound's reactivity and biological activity. This opens a realm of possibilities for diversified applications, as varying the substituents can lead to tailored compounds for specific functions.
  • Research Significance: In recent studies, piperidine derivatives have been researched for their ability to act as ligands in coordination chemistry and catalysis. Their unique electronic and steric properties can enhance chemical reactivity, making them valuable in various synthesis processes.

In conclusion, the compound 5-ethyl-2-methyl-piperidine exemplifies the rich chemistry of piperidine derivatives. From its potential in drug development to its application in synthesis, understanding this compound can pave the way for advancements in various chemical and pharmaceutical fields. As we continue to explore these types of compounds, we open the door to new discoveries and innovations!

Synonyms
5-Ethyl-2-methylpiperidine
104-89-2
Copellidine
Copellidin
Piperidine, 5-ethyl-2-methyl-
2-METHYL-5-ETHYLPIPERIDINE
2-Pipecoline, 5-ethyl-
3-Ethyl-6-methylpiperidine
5-Ethyl-2-pipecoline
NSC 6119
EINECS 203-249-5
BRN 0079909
DTXSID00870447
4-20-00-01622 (Beilstein Handbook Reference)
(2R,5R)-5-ethyl-2-methylpiperidine
1969288-69-4
MFCD00023134
SCHEMBL26639
WLN: T6MTJ B1 E2
DTXCID20818169
NSC6119
AAA10489
NSC-6119
STL585040
AKOS006229621
PIPERIDINE,5-ETHYL-2-METHYL-
CS-0239129
NS00041360
EN300-206264
203-249-5