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5-Chloro-N-heptyl-naphthalene-1-sulfonamide

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Identification
Molecular formula
C17H20ClNO2S
CAS number
118759-78-1
IUPAC name
5-chloro-N-heptyl-naphthalene-1-sulfonamide
State
State

This compound is a solid at room temperature, which is typical for sulfonamides with a substituted naphthalene base.

Melting point (Celsius)
135.00
Melting point (Kelvin)
408.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
371.93g/mol
Molar mass
371.9280g/mol
Density
0.0000g/cm3
Appearence

5-Chloro-N-heptyl-naphthalene-1-sulfonamide typically appears as a crystalline solid with a distinct naphthalene-like odor. The color can vary depending on purity but it is often white to off-white.

Comment on solubility

Solubility of 5-chloro-N-heptyl-naphthalene-1-sulfonamide

The solubility of 5-chloro-N-heptyl-naphthalene-1-sulfonamide (C17H20ClNO2S) can vary significantly based on the medium and conditions. This compound, being an aromatic sulfonamide, typically exhibits the following solubility characteristics:

  • Polar Solvents: It tends to have limited solubility in polar solvents such as water due to the hydrophobic nature of its naphthalene ring and heptyl group.
  • Non-Polar Solvents: In contrast, this compound is likely to be more soluble in non-polar organic solvents like toluene or hexane where its hydrophobic properties can engage effectively.
  • Temperature Influence: Solubility can also be influenced by temperature; typically, warmer temperatures may enhance solubility in organic solvents.
  • pH Sensitivity: The presence of the sulfonamide group allows for some environmental pH sensitivity, where solubility might increase in alkaline conditions.

Overall, the solubility profile of this compound is a blend of its structural attributes and the nature of the solvent used. As with many organic compounds, understanding these interactions is crucial for predicting behavior in different chemical environments.

Interesting facts

Interesting Facts about 5-chloro-N-heptyl-naphthalene-1-sulfonamide

5-chloro-N-heptyl-naphthalene-1-sulfonamide is an intriguing compound that falls into the category of sulfonamides, which are known for their diverse applications in medicinal chemistry. Below are some fascinating points about this compound:

  • Sulfonamide Backbone: The sulfonamide functional group is crucial in drug design, particularly for antibiotics, as it inhibits bacterial growth by interfering with folic acid synthesis.
  • Chlorine Atom Impact: The presence of chlorine in the structure can enhance the compound's biological activity and can affect its lipophilicity, potentially improving its ability to penetrate biological membranes.
  • Heptyl Chain: The N-heptyl group contributes to the lipophilicity of the compound, which may affect how it interacts with biological systems and contributes to its pharmacological properties.
  • Applications: Compounds in this family are often explored for their anti-inflammatory and antibacterial properties. There is significant research interest in modifying existing sulfonamides to increase efficacy and reduce side effects.
  • Chemical Versatility: This compound can serve as a starting point for synthesizing various analogs, allowing researchers to explore a broader spectrum of biological activities.

As a scientist delving into the world of sulfonamides, the study of compounds like 5-chloro-N-heptyl-naphthalene-1-sulfonamide highlights the balance of structural features that influence biological interactions. The exploration of these kinds of compounds continues to be an important aspect of developing new therapeutic agents.
"Chemistry is the reduction of the infinite onto the finite, and every molecule tells a story."

Synonyms
sc-10
102649-79-6
5-chloro-N-heptylnaphthalene-1-sulfonamide
5-Chloro-N-heptyl-1-naphthalenesulfonamide
1-Naphthalenesulfonamide, 5-chloro-N-heptyl-
SC 10
N-Heptyl-5-chloro-1-naphthalene-sulfonamide
N-(N-HEPTYL)-5-CHLORO-1-NAPHTHALENESULFONAMIDE
NCGC00024585-01
Tocris-0430
N-(m-Heptyl)-5-chloro-1-naphthalenesulfonamide
SCHEMBL317323
CHEMBL1397913
CHEBI:92094
DTXSID10907970
GLXC-04365
HMS3266O09
HMS3411K11
HMS3675K11
HSCI1_000372
AKOS024458082
SB83257
HY-100931
CS-0020602
SR-01000597643
SR-01000597643-1
BRD-K05361803-001-01-3
BRD-K05361803-001-02-1
BRD-K05361803-001-03-9
Q27163886