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(5-Chloro-8-quinolinyl) acetate

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Identification
Molecular formula
C11H8ClNO2
CAS number
554-86-5
IUPAC name
(5-chloro-8-quinolyl) acetate
State
State

At room temperature, (5-Chloro-8-quinolinyl) acetate is typically a solid.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
407.00
Boiling point (Kelvin)
680.15
General information
Molecular weight
235.64g/mol
Molar mass
235.6640g/mol
Density
1.4000g/cm3
Appearence

The compound appears as a pale yellow crystalline powder.

Comment on solubility

Solubility of (5-chloro-8-quinolyl) acetate (C11H8ClNO2)

(5-chloro-8-quinolyl) acetate exhibits specific solubility characteristics that can influence its applications in various fields. The solubility of this compound can be summarized as follows:

  • Solvent Compatibility: It is generally soluble in organic solvents such as ethanol and acetone.
  • Water Solubility: Its solubility in water is quite limited, which can be attributed to its relatively hydrophobic nature due to the presence of the quinoline moiety.
  • Temperature Dependency: Like many organic compounds, solubility may improve with increasing temperature, allowing for greater dissolution in solvents.

It is worth noting that the solubility of (5-chloro-8-quinolyl) acetate can be affected by:

  1. The pH of the solution, as it may ionize in more alkaline or acidic conditions.
  2. The presence of other solutes which can create competition for solvation.

In summary, the solubility of (5-chloro-8-quinolyl) acetate can be considered moderate in organic solvents, while being relatively insoluble in water. Understanding these solubility properties is crucial, especially for applications in synthesis and formulation.

Interesting facts

Interesting Facts about (5-chloro-8-quinolyl) acetate

(5-chloro-8-quinolyl) acetate is a fascinating compound within the world of organic chemistry. Known for its unique structure, this compound has attracted attention for several reasons:

  • Unique Structure: This compound features a quinoline backbone, characterized by a bicyclic aromatic structure that contributes to its chemical reactivity and stability. The incorporation of a chlorine atom at the 5-position adds an interesting twist, impacting both its electronic properties and its potential applications.
  • Biological Activity: Compounds derived from quinoline structures are often explored in medicinal chemistry. They are known to exhibit a range of biological activities, including antibacterial, antiviral, and antimalarial properties. Research suggests that (5-chloro-8-quinolyl) acetate could potentially be investigated for similar therapeutic uses.
  • Applications in Materials Science: The unique properties of (5-chloro-8-quinolyl) acetate make it an attractive candidate for various applications, such as in the development of dyes, pigments, and other specialty chemicals. Its ability to form complexes with metal ions is particularly notable.
  • Research Potential: The ongoing studies into the reactivity and modifications of this compound could lead to the discovery of new derivatives with enhanced properties, expanding its applicability in pharmaceuticals and materials.
  • Historical Significance: The quinoline family, from which this compound is derived, has a rich history in chemistry, with roots tracing back to the early 19th century. This lineage adds a historical dimension to its study, making it not just a modern compound but also a piece of chemical history.

In summary, (5-chloro-8-quinolyl) acetate stands as a compound of significant interest not just due to its chemical attributes but also due to its potential applications across various fields, making it a worthy subject for further exploration in the realm of chemistry.

Synonyms
chloroacetoxyquinoline
KBio1_000423
Spectrum_001695
Spectrum2_000867
Spectrum5_001169
KBioSS_002175
DivK1c_000423
SPECTRUM1503341
SPBio_000913
SCHEMBL3691077
CHEMBL1450499
HMS501F05
KBio2_002175
KBio2_004743
KBio2_007311
NINDS_000423
HMS1922A18
CCG-40312
IDI1_000423
NCGC00095044-01
NCGC00095044-02
BRD-K98737600-001-02-5