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5-chloro-6-hydroxybenzoxazolinone

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Identification
Molecular formula
C7H4ClNO3
CAS number
103187-55-7
IUPAC name
5-chloro-6-hydroxy-3H-1,3-benzoxazol-2-one
State
State

At room temperature, 5-Chloro-6-hydroxybenzoxazolinone is in a solid state, specifically as a crystalline powder. This provides ease of handling and measurement in various chemical processes.

Melting point (Celsius)
283.00
Melting point (Kelvin)
556.15
Boiling point (Celsius)
270.00
Boiling point (Kelvin)
543.15
General information
Molecular weight
199.57g/mol
Molar mass
199.5800g/mol
Density
1.7480g/cm3
Appearence

5-Chloro-6-hydroxybenzoxazolinone appears as a white to off-white crystalline powder. Its appearance is characterized by its solid-state and fine powder form that may exhibit slight variations in shade.

Comment on solubility

Solubility of 5-chloro-6-hydroxy-3H-1,3-benzoxazol-2-one (C7H4ClNO3)

The solubility of 5-chloro-6-hydroxy-3H-1,3-benzoxazol-2-one exhibits some interesting characteristics that can affect its applications in various contexts. Understanding these solubility traits is crucial for its use in chemical processes and formulations. Here are several key points to consider:

  • Polar Characteristics: The presence of the hydroxy (-OH) group and the chlorine atom contributes to the molecule's polarity, potentially increasing its solubility in polar solvents such as water and alcohol.
  • Hydrogen Bonding: The hydroxyl group allows for the possibility of hydrogen bonding with other molecules, which may enhance solubility in aqueous environments.
  • Dissolution in Organic Solvents: Solubility may also extend to organic solvents, such as ethanol and methanol, making it versatile for use in organic reactions.

However, the solubility of 5-chloro-6-hydroxy-3H-1,3-benzoxazol-2-one can be influenced by several factors:

  • Temperature: Increased temperature generally enhances solubility for many compounds, which could also apply to this benzoxazole derivative.
  • pH Levels: Changes in pH may affect the ionization states of the compound, further influencing its solubility dynamics.
  • Presence of Salts: The solubility could be affected by the common ion effect when salts are present in the solution.

In summary, 5-chloro-6-hydroxy-3H-1,3-benzoxazol-2-one presents a blend of polar characteristics and potential for hydrogen bonding, which may contribute positively to its solubility in water and organic solvents, although various external factors can modulate this behavior. Understanding these aspects is key to harnessing its full potential in practical applications.

Interesting facts

Interesting Facts about 5-chloro-6-hydroxy-3H-1,3-benzoxazol-2-one

5-chloro-6-hydroxy-3H-1,3-benzoxazol-2-one is a fascinating compound that belongs to the class of benzoxazoles, which are known for their diverse biological activities. Here are some interesting facts about this intriguing chemical:

  • Biological Significance: This compound has demonstrated notable antimicrobial properties, making it a potential candidate for the development of new antibacterial and antifungal agents.
  • Fluorescence: Some derivatives of benzoxazoles exhibit interesting fluorescent properties which can be harnessed in various applications, including biological imaging and sensing technologies.
  • Structural Versatility: The presence of a chlorine atom and a hydroxy group on the benzoxazole ring allows for the potential modification of the molecule, leading to the synthesis of a wide range of analogs that can possess different pharmacological activities.
  • Reaction Mechanisms: The reactivity patterns of benzoxazoles, including electrophilic aromatic substitution, are of particular interest to chemists aiming to explore novel synthetic methodologies.
  • Analytical Applications: This compound can serve as a valuable reagent in analytical chemistry, especially in the detection of certain metal ions through specific colorimetric changes.

In summary, 5-chloro-6-hydroxy-3H-1,3-benzoxazol-2-one is not just a compound; it's a stepping stone to discovering new medicinal agents and advancing our understanding of chemical reactivity. As we continue to explore its properties and applications, this compound may prove to be a vital part of future scientific breakthroughs.

Synonyms
6-Hydroxychlorzoxazone
1750-45-4
6-hydroxy Chlorzoxazone
5-Chloro-6-hydroxybenzo[d]oxazol-2(3H)-one
2(3H)-Benzoxazolone, 5-chloro-6-hydroxy-
5-chloro-6-hydroxy-3H-1,3-benzoxazol-2-one
5-Chloro-6-hydroxy-2-benzoxazolinone
5-Chloro-6-hydroxybenzoxazone
NSC 24955
2-BENZOXAZOLINONE, 5-CHLORO-6-HYDROXY-
M5YLT4Y73F
BRN 0911674
NSC-24955
UNII-M5YLT4Y73F
DTXSID50169919
MFCD00143502
5-Chloro-6-hydroxy-2(3H)-benzoxazolone
5-chloro-6-hydroxy-1,3-benzoxazol-2(3h)-one
6-Hydroxy-chlorzoxazone
6-Hydroxychlorzoxazone, solid
SCHEMBL528197
CHEMBL3182250
DTXCID9092410
CHEBI:184399
NSC24955
AKOS006275736
CS-W016937
FH23939
HY-W016221
NCGC00165920-01
6-Hydroxychlorzoxazone, >=98% (HPLC)
PD019845
NS00115884
C73343
5- chloro- 6- hydroxy- 2(3H)- benzoxazolone
2(3H)-Benzoxazolone, 5-chloro-6-hydroxy-(9CI)
5-Chloro-6-hydroxybenZo[d]oxaZol-2(3H)-one, 95%
Q61721231
5-Chloro-6-hydroxy-2(3H)-benzoxazolone;6-Hydroxychlorzoxazone;NSC 24955