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TTP488

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Identification
Molecular formula
C16H18ClN3O3S
CAS number
603336-53-3
IUPAC name
5-chloro-3-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxo-ethyl]-1,3-benzothiazol-2-one
State
State

At room temperature, TTP488 is typically found in a solid state. This solid is often used in drug development and medical research.

Melting point (Celsius)
211.00
Melting point (Kelvin)
484.15
Boiling point (Celsius)
773.15
Boiling point (Kelvin)
500.00
General information
Molecular weight
372.83g/mol
Molar mass
372.8330g/mol
Density
1.4966g/cm3
Appearence

TTP488 appears as an off-white to pale yellow solid. It may be presented in various forms for research or pharmaceutical use, such as powder or crystalline solid.

Comment on solubility

Solubility Characteristics of 5-Chloro-3-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxo-ethyl]-1,3-benzothiazol-2-one

The solubility of 5-chloro-3-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxo-ethyl]-1,3-benzothiazol-2-one (C16H18ClN3O3S) is an interesting subject, largely influenced by its complex molecular structure. Understanding its solubility can be approached by examining several key factors:

  • Polarity: The presence of polar functional groups, such as the -OH (hydroxy) and the piperazine moiety, suggests that this compound may exhibit some degree of solubility in polar solvents like water.
  • Hydrophobic and Hydrophilic Balance: Given its aromatic components and the chloro substituent, the molecule may also have hydrophobic characteristics that could limit its solubility in aqueous solutions.
  • Solvent Choice: As a general rule, solubility is enhanced when using solvents that can interact favorably with the solute. Thus, this compound might dissolve better in organic solvents, such as ethanol or DMSO, compared to water.
  • pH Dependence: The solubility may also vary with pH, especially due to the presence of functional groups that can potentially ionize under different conditions.

As illustrated, the solubility of this compound can be predicted based on a careful assessment of its structural features and environmental conditions. Understanding these parameters is essential when considering the application of this compound in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about 5-Chloro-3-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxo-ethyl]-1,3-benzothiazol-2-one

5-Chloro-3-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxo-ethyl]-1,3-benzothiazol-2-one is a fascinating compound with numerous applications in the field of medicinal chemistry. Here are some key points of interest:

  • Mechanism of Action: The compound has shown potential as a therapeutic agent, particularly in the treatment of various diseases, due to its ability to interact with biological pathways.
  • Structural Complexity: Its structure features a unique combination of a benzothiazole ring and a piperazine moiety, which contribute to its biological activity and solubility profile.
  • Biological Significance: Compounds like this one are often evaluated for their effects on cell signaling, and their unique combination of functionality may lead to promising results in cancer research.
  • Research Applications: Investigators have explored its characteristics in various domains, including pharmacology and drug development, utilizing its distinctive properties to design more effective pharmaceuticals.

As a chemical scientist, one must appreciate the intricate balance between a compound's chemical structure and its biological interface. This compound serves as a potent reminder that even subtle modifications in molecular design can lead to significant changes in efficacy and potency.

In conclusion, the study of 5-chloro-3-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxo-ethyl]-1,3-benzothiazol-2-one not only enhances our understanding of chemical agents but also inspires further exploration and innovation in the development of new therapeutic solutions.

Synonyms
TIARAMIDE
32527-55-2
tialamide
Tiaramida
RHC 2592A
Tiaramidum
USV 2592
Tiaramide [INN:BAN]
Tiaramidum [INN-Latin]
Tiaramida [INN-Spanish]
EINECS 251-083-7
UNII-BB17WGM686
Tiaramide (INN)
BRN 1030245
BB17WGM686
RHC-2592A
TIARAMIDE [INN]
TIARAMIDE [MI]
TIARAMIDE [WHO-DD]
5-chloro-3-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxoethyl]-1,3-benzothiazol-2-one
DTXSID0023666
FK 1160
5-Chlor-2,3-dihydro-3-(4-(2-hydroxyethyl)piperazinylcarbonylmethyl)-2-benzothiazolon
Solantal (TN)
Tiaramidum (INN-Latin)
Tiaramida (INN-Spanish)
1-Piperazineethanol, 4-((5-chloro-2-oxo-3(2H)-benzothiazolyl)acetyl)-
1-Piperazineethanol, 4-((5-chloro-2-oxo-3-benzothiazolinyl)acetyl)-
4-((5-Chloro-2-oxo-3(2H)-benzothiazolyl)acetyl)-1-piperazineethanol
1-PIPERAZINEETHANOL, 4-((5-CHLORO-2-OXO-3(2H)-BENZOTHIAZOLYL)ACETYL)
1-Piperazineethanol, 4-[(5-chloro-2-oxo-3(2H)-benzothiazolyl)acetyl]-
2(3H)-BENZOTHIAZOLONE, 5-CHLORO-3-(2-(4-(2-HYDROXYETHYL)-1-PIPERAZINYL)-2-OXOETHYL)-
NSC289337
Oprea1_708738
SCHEMBL25172
CHEMBL274239
DTXCID703666
CHEBI:135504
HTJXMOGUGMSZOG-UHFFFAOYSA-N
NS00029292
D08592
G66618
SBI-0654651.0001
SR-01000944979
SR-01000944979-1
BRD-K27293958-001-01-5
Q27274575
1-Piperazineethanol, 4-((5-chloro-2-oxo-3(2H)-benzothiazolyl)acetyl)-(9CI)
5-chloro-3-[2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxo-ethyl]-1,3-benzothiazol-2-one
5-chloro-3-{2-[4-(2-hydroxyethyl)-1-piperazinyl]-2-oxoethyl}-1,3-benzothiazol-2(3H)-one
5-chloro-3-{2-[4-(2-hydroxyethyl)piperazin-1-yl]-2-oxoethyl}-1,3-benzothiazol-2(3H)-one
251-083-7